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Comprehensive Enantioselective Organocatalysis: Catalysts, Reactions, and Applications

Open access
·2013·Wiley eBooks

Abstract

VOLUME ONE - Privileged Catalysts PART I: AMINO ACID-DERIVED CATALYSTS Proline-Related Secondary Amine Catalysts and Applications TMS-Prolinol Catalyst in Organocatalysis Non-Proline Amino Acid Catalysts Chiral Imidazolidinone (MacMillan's Catalyst) Oligopeptides as Modular Organocatalytic Scaffolds PART II: NON-AMINO ACID-DERIVED CATALYSTS Cinchonas and Cupreidines Chiral C2 Catalysts Planar Chiral Catalysts Dynamic Approaches towards Catalyst Discovery VOLUME TWO - Activations PART I: ASYMMETRIC CATALYSIS WITH NON-COVALENT INTERACTIONS Bronsted Acids Bronsted Acids: Chiral Phosphoric Acid Catalysts in Asymmetric Synthesis Bronsted Acids: Chiral (Thio)urea Derivatives Bronsted Bases Chiral Onium Salts (Phase-Transfer Reactions) Lewis Bases Lewis Acids PART II: ASYMMETRIC CATALYSIS WITH COVALENT INTERACTIONS Rationalizing Reactivity and Selectivity in Aminocatalytic Reactions Carbene Catalysts Oxides and Epoxides Ylides PART III: TUNING CATALYST ACTIVITY AND SELECTIVITY BY THE REACTION MEDIUM AND CONDITIONS Non-Classical Activation of Organocatalytic Reactions (Pressure, Microwave Irradiation) Ionic Liquid Organocatalysts Polymer and Mesoporous Material Supported Organocatalysts Water in Organocatalytic Reactions VOLUME THREE - Reactions and Applications PART I: ALPHA-ALKYLATION AND HETEROATOM FUNCTIONALIZATION SN2-Type Alpha-Alkylation and Allylation Reactions Alpha-Alkylation by SN1-Type Reactions Alpha-Heteroatom Functionalization of Carbonyl Compounds PART II: NUCLEOPHILE ADDITION TO C=X BONDS Aldol and Mannich-Type Reactions Additions of Nitroalkyls and Sulfones to C=X Hydrocyanation and Strecker Reactions The Morita-Baylis-Hillman (MBH) and Hetero-MBH Reactions Reduction of C=O and C=N PART III: NUCLEOPHILE ADDITION TO C=C BONDS Addition to Alpha, Beta-Unsaturated Aldehydes and Ketones Addition to Nitroolefins and Vinyl Sulfones Organocatalyzed Asymmetric Arylation and Heteroarylation Reactions PART IV: RING-FORMING REACTIONS Intramolecular Reactions Formation of 3-, 4- and 5-Membered Cycles by Intermolecular Reactions Diels-Alder and Hetero-Diels-Alder Reactions PART V: INCREASING COMPLEXITY Organocatalytic Radical and Electron Transfer Reactions Organocatalytic Sigmatropic Reactions Regio- and Position Selective Reactions and Desymmetrizations Three or More Components Reactions (Single Catalyst Systems) Multi-Catalyst Systems Organocatalysis in Total Synthesis

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Metadata

Venue
Wiley eBooks
Publisher
Wiley
Published
2013-08-23
OpenAlex
W344856349
Cited by
368
References
0
FWCI
11.89
Type
book
Language
en
Open access
green

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Comprehensive Enantioselective Organocatalysis: Catalysts, Reactions, and Applications. (2013). Wiley eBooks. https://doi.org/10.1002/9783527658862

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