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Dual Phase‐Controlled Synthesis of Uniform Lanthanide‐Doped NaGdF4 Upconversion Nanocrystals Via an OA/Ionic Liquid Two‐Phase System for In Vivo Dual‐Modality Imaging

Open access
He, Meng, Huang, Peng, Zhang, Chunlei, Hu, Hengyao, Bao, Chenchen, Gao, Guo, He, Rong, Cui, Daxiang·2011·Advanced Functional Materials

Abstract

A novel OA/ionic liquid two‐phase system combining the merits of thermal decomposition method, the IL‐based strategy, and the two‐phase approach is introduced to synthesize high‐quality lanthanide‐doped NaGdF 4 upconversion nanocrystals with different crystal‐phases in OA‐phase and IL‐phase through a one‐step controllable reaction. Oil‐dispersible cubic‐phase NaGdF 4:Yb, Er (Ho, Tm) nanocrystals with ultra‐small size (∼5 nm) and monodispersity are obtained in the OA phase of the two‐phase system via an IL‐based reaction. More importantly, water‐soluble hexagonal‐phase NaGdF 4:Yb, Er nanocrystals are obtained in the same system simply by adopting an extremely facile method to complete the dual phase‐transition (crystal‐phase transition and OA‐phase to IL‐phase transition) simultaneously. The synthesized lanthanide‐doped NaGdF 4 upconversion nanocrystals are effective for dual‐mode UCL imaging and CT imaging in vivo.

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Metadata

Authors
He, M., Huang, P., Zhang, C., Hu, H., Bao, C., Gao, G., He, R., & Cui, D.
Venue
Advanced Functional Materials
Publisher
Wiley
Published
2011-09-22
Volume
21
Issue
23
Pages
4470-4477
ISSN
  • 1616-301X (ISSN-L)
  • 1616-3028
OpenAlex
W2034291685
Cited by
238
References
2
FWCI
17.04
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Dual Phase‐Controlled Synthesis of Uniform Lanthanide‐Doped NaGdF4 Upconversion Nanocrystals Via an OA/Ionic Liquid Two‐Phase System for In Vivo Dual‐Modality Imaging. https://app.cochat.ai/papers/10.1002/adfm.201101040
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He, M., Huang, P., Zhang, C., Hu, H., Bao, C., Gao, G., He, R., & Cui, D. (2011). Dual Phase‐Controlled Synthesis of Uniform Lanthanide‐Doped NaGdF4 Upconversion Nanocrystals Via an OA/Ionic Liquid Two‐Phase System for In Vivo Dual‐Modality Imaging. Advanced Functional Materials. https://doi.org/10.1002/adfm.201101040

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