The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A Versatile Nanotheranostic Agent for Efficient Dual‐Mode Imaging Guided Synergistic Chemo‐Thermal Tumor Therapy
Abstract
The integration of efficient imaging for diagnosis and synergistic tumor therapy into a single‐component nanoplatform is much promising for high efficacy tumor treatment but still in a great challenge. Herein, a smart and versatile nanotheranostic platform based on hollow mesoporous Prussian blue nanoparticles (HMPBs) with perfluoropentane (PFP) and doxorubicin (DOX) inside, has been designed, for the first time, to achieve the distinct in vivo synergistic chemo‐thermal tumor therapy and synchronous diagnosis and monitoring by ultrasound (US)/photoacoustic (PA) dual mode imaging. The prepared HMPBs show excellent photothermal conversion properties with large molar extinction coefficient (≈1.2 × 10 11m−1 cm−1) and extremely high photothermal conversion efficiency (41.4%). Such a novel theranostic nanoplatform is expected to overcome the inevitable tumor recurrence and metastasis resulting from the inhomogeneous ablation of single thermal therapy, which will find a promising prospect in the application of noninvasive cancer therapy.
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Citations
Cites
Photoacoustic tomography: In vivo imaging from organelles to organs
Wang, L. V., & Hu, S. (2012) · Science · doi:10.1126/science.1216210 · Cited by 4,331
Cited by
Synthesis, Properties, and Applications of Hollow Micro-/Nanostructures
Wang, X., Feng, J., Bai, Y., Zhang, Q., & Yin, Y. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00731 · Cited by 1,456
Current Approaches of Photothermal Therapy in Treating Cancer Metastasis with Nanotherapeutics
Zou, L., Wang, H., He, B., Zeng, L., Tan, T., Cao, H., He, X., Zhang, Z., Guo, S., & Li, Y. (2016) · Theranostics · doi:10.7150/thno.14988 · Cited by 915
Conquering the Hypoxia Limitation for Photodynamic Therapy
Wan, Y., Fu, L., Li, C., Lin, J., & Huang, P. (2021) · Advanced Materials · doi:10.1002/adma.202103978 · Cited by 705
Theranostic 2D Tantalum Carbide (MXene)
Lin, H., Wang, Y., Gao, S., Chen, Y., & Shi, J. (2018) · Advanced Materials · doi:10.1002/adma.201703284 · Cited by 606
Self-citationSong, G., Liang, C., Yi, X., Zhao, Q., Cheng, L., Yang, K., & Liu, Z. (2016) · Advanced Materials · doi:10.1002/adma.201504617 · Cited by 587
Metadata
- Authors
- Cai, X., Jia, X., Gao, W., Zhang, K., Ma, M., Wang, S., Zheng, Y., Shi, J., & Chen, H.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2015-02-27
- Volume
- 25
- Issue
- 17
- Pages
- 2520-2529
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2088922707
- Cited by
- 184
- References
- 1
- FWCI
- 11.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cai, X., Jia, X., Gao, W., Zhang, K., Ma, M., Wang, S., Zheng, Y., Shi, J., & Chen, H. (2015). A Versatile Nanotheranostic Agent for Efficient Dual‐Mode Imaging Guided Synergistic Chemo‐Thermal Tumor Therapy. Advanced Functional Materials. https://doi.org/10.1002/adfm.201403991
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