Blood‐Brain Barrier‐Penetrating Nanocarriers Enable Microglial‐Specific Drug Delivery in Hypothalamic Neuroinflammation

Glutathione: overview of its protective roles, measurement, and biosynthesis

Forman, H. J., Zhang, H., & Rinna, A. (2009) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2008.08.006 · Cited by 2,636 · see citing works

Cachexia: a new definition.

Evans, W., Morley, J., Argilés, J., Bales, C., Baracos, V., Guttridge, D., Jatoi, A., Kalantar-zadeh, K., Lochs, H., Mantovani, G., et al. (2008) · Clinical Nutrition · doi:10.1016/j.clnu.2008.06.013 · Cited by 2,341 · see citing works

An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger

Krashes, M. J., Shah, B. P., Madara, J. C., Olson, D. P., Strochlic, D. E., Garfield, A. S., Vong, L., Pei, H., Watabe-Uchida, M., Uchida, N., et al. (2014) · Nature · doi:10.1038/nature12956 · Cited by 603 · see citing works

PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application

Grossen, P., Witzigmann, D., Sieber, S., & Huwyler, J. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.05.028 · Cited by 503 · see citing works

MC4R-dependent suppression of appetite by bone-derived lipocalin 2

Mosialou, I., Shikhel, S., Liu, J., Maurizi, A., Luo, N., He, Z., Huang, Y., Zong, H., Friedman, R. A., Barasch, J. M., et al. (2017) · Nature · doi:10.1038/nature21697 · Cited by 457 · see citing works

Elaborations on the Higuchi model for drug delivery

Paul, D. R. (2010) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2010.10.037 · Cited by 355 · see citing works

Pathway across the blood–brain barrier

Ek, M., Engblom, D., Saha, S., Blomqvist, A. G., Jakobsson, P., & Ericsson‐Dahlstrand, A. (2001) · Nature · doi:10.1038/35068632 · Cited by 347 · see citing works

Anti-glioblastoma efficacy and safety of paclitaxel-loading Angiopep-conjugated dual targeting PEG-PCL nanoparticles

Xin, H., Sha, X., Jiang, X., Zhang, W., Chen, L., & Fang, X. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.07.046 · Cited by 311 · see citing works

A brain microvasculature endothelial cell‐specific viral vector with the potential to treat neurovascular and neurological diseases

Körbelin, J., Dogbevia, G., Michelfelder, S., Ridder, D. A., Hunger, A., Wenzel, J., Seismann, H., Lampe, M., Bannach, J., Pasparakis, M., et al. (2016) · EMBO Molecular Medicine · doi:10.15252/emmm.201506078 · Cited by 243 · see citing works

Controlled Drug Release from Nanoengineered Polysaccharides

Bayer, I. S. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15051364 · Cited by 231 · see citing works

Microglial immunophenotype in dementia with Alzheimer’s pathology

CFAS, M., Minett, T., Classey, J., Matthews, F. E., Fahrenhold, M., Taga, M., Brayne, C., Ince, P. G., Nicoll, J. A. R., & Boche, D. (2016) · Journal of Neuroinflammation · doi:10.1186/s12974-016-0601-z · Cited by 219 · see citing works

Biocompatible Nanoclusters with High Heating Efficiency for Systemically Delivered Magnetic Hyperthermia

Albarqi, H. A., Wong, L., Schumann, C., Sabei, F. Y., Korzun, T., Li, X., Hansen, M. N., Dhagat, P., Moses, A. S., Taratula, O. R., et al. (2019) · ACS Nano · doi:10.1021/acsnano.8b06542 · Cited by 216 · see citing works

Loading and in vitro release of ibuprofen in tubular halloysite

Tan, D., Yuan, P., Bergaya, F., Liu, D., Wang, L., Liu, H., & He, H. (2014) · Applied Clay Science · doi:10.1016/j.clay.2014.01.018 · Cited by 177 · see citing works

Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease

Wang, P., Zheng, X., Guo, Q., Yang, P., Pang, X., Qian, K., Lü, W., Zhang, Q., & Jiang, X. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.04.034 · Cited by 162 · see citing works

Discovery of Clinical Candidate 1-{[(2 S ,3 S ,4 S )-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design

Lee, K. L., Ambler, C. M., Anderson, D. R., Boscoe, B. P., Bree, A. G., Brodfuehrer, J., Chang, J. S., Choi, C., Chung, S., Curran, K. J., et al. (2017) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.7b00231 · Cited by 162 · see citing works

Hypothalamic mechanisms in cachexia

Grossberg, A. J., Scarlett, J. M., & Marks, D. L. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.03.011 · Cited by 160 · see citing works

IRAK-4 Inhibitors for Inflammation

Wang, Z., Wesche, H., Stevens, T., Walker, N. P. C., & Yeh, W. (2009) · Current Topics in Medicinal Chemistry · doi:10.2174/156802609789044407 · Cited by 149 · see citing works

Establishment and characterization of a novel murine model of pancreatic cancer cachexia

Michaelis, K. A., Zhu, X., Burfeind, K. G., Krasnow, S. M., Levasseur, P. R., Morgan, T. K., & Marks, D. L. (2017) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12225 · Cited by 148 · see citing works

Engineered Nanoerythrocytes Alleviate Central Nervous System Inflammation by Regulating the Polarization of Inflammatory Microglia

Yin, N., Zhao, Y., Liu, C., Yang, Y., Wang, Z., Yu, W., Zhang, K., Zhang, Z., Liu, J., Zhang, Y., et al. (2022) · Advanced Materials · doi:10.1002/adma.202201322 · Cited by 136 · see citing works

Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia

Olson, B. G., Zhu, X., Norgard, M. A., Levasseur, P. R., Butler, J. T., Buenafe, A. C., Burfeind, K. G., Michaelis, K. A., Pelz, K. R., Mendez, H., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22361-3 · Cited by 124 · see citing works

Microglia-targeting nanotherapeutics for neurodegenerative diseases

Zhao, N., Francis, N. L., Calvelli, H. R., & Moghe, P. V. (2020) · APL Bioengineering · doi:10.1063/5.0013178 · Cited by 104 · see citing works

Reduced secretion of LCN2 (lipocalin 2) from reactive astrocytes through autophagic and proteasomal regulation alleviates inflammatory stress and neuronal damage

Jung, B.-K., Park, Y., Yoon, B., Bae, J.-S., Han, S.-W., Heo, J. E., Kim, D., & Ryu, K. (2023) · Autophagy · doi:10.1080/15548627.2023.2180202 · Cited by 104 · see citing works

A dual-ligand fusion peptide improves the brain-neuron targeting of nanocarriers in Alzheimer's disease mice

Guo, Q., Xu, S., Yang, P., Wang, P., Lü, S., Sheng, D., Qian, K., Cao, J., Lü, W., & Zhang, Q. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.01.039 · Cited by 103 · see citing works

Mannose-Integrated Nanoparticle Hitchhike Glucose Transporter 1 Recycling to Overcome Various Barriers of Oral Delivery for Alzheimer’s Disease Therapy

Lei, T., Yang, Z., Jiang, C., Wang, X., Yang, W., Yang, X., Xie, R., Tong, F., Xia, X., Huang, Q., et al. (2024) · ACS Nano · doi:10.1021/acsnano.3c09715 · Cited by 98 · see citing works

The Interleukin‐1 Receptor–Associated Kinase 4 Inhibitor PF‐06650833 Blocks Inflammation in Preclinical Models of Rheumatic Disease and in Humans Enrolled in a Randomized Clinical Trial

Winkler, A. R., Sun, W., De, S., Jiao, A., Sharif, M., Symanowicz, P. T., Athale, S., Shin, J. H., Wang, J., Jacobson, B. A., et al. (2021) · Arthritis & Rheumatology · doi:10.1002/art.41953 · Cited by 93 · see citing works

Biodegradable diblock copolymeric PEG-PCL nanoparticles: Synthesis, characterization and applications as anticancer drug delivery agents

Behl, A., Parmar, V. S., Malhotra, S., & Chhillar, A. K. (2020) · Polymer · doi:10.1016/j.polymer.2020.122901 · Cited by 92 · see citing works

Gene Therapy for Neuropathic Pain through siRNA-IRF5 Gene Delivery with Homing Peptides to Microglia

Terashima, T., Ogawa, N., Nakae, Y., Sato, T., Katagi, M., Okano, J., Maegawa, H., & Kojima, H. (2018) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2018.02.007 · Cited by 77 · see citing works

MicroRNA367 negatively regulates the inflammatory response of microglia by targeting IRAK4 in intracerebral hemorrhage

Yuan, B., Shen, H., Lin, L., Su, T., Zhong, L., & Yang, Z. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0424-3 · Cited by 72 · see citing works

Boosting RNAi therapy for orthotopic glioblastoma with nontoxic brain-targeting chimaeric polymersomes

Shi, Y., Jiang, Y., Cao, J., Yang, W., Zhang, J., Meng, F., & Zhong, Z. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.10.034 · Cited by 71 · see citing works

A hybrid siRNA delivery complex for enhanced brain penetration and precise amyloid plaque targeting in Alzheimer’s disease mice

Zheng, X., Pang, X., Yang, P., Xu, W., Wei, Y., Guo, Q., Zhang, Q., & Jiang, X. (2016) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.11.029 · Cited by 68 · see citing works

Multifunctional Selenium Nanoparticles with Different Surface Modifications Ameliorate Neuroinflammation through the Gut Microbiota-NLRP3 Inflammasome-Brain Axis in APP/PS1 Mice

Yang, L., Cui, Y., Liang, H., Li, Z., Wang, N., Wang, Y., & Zheng, G. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c06283 · Cited by 67 · see citing works

Safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06650833, a selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor, in single and multiple ascending dose randomized phase 1 studies in healthy subjects

Danto, S. I., Shojaee, N., Singh, R. S. P., Li, C., Gilbert, S. A., Manukyan, Z., & Kilty, I. (2019) · Arthritis Research & Therapy · doi:10.1186/s13075-019-2008-6 · Cited by 67 · see citing works

MicroRNA-27a Negatively Modulates the Inflammatory Response in Lipopolysaccharide-Stimulated Microglia by Targeting TLR4 and IRAK4

Lv, Y., Ouyang, A., & Fu, L. (2016) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-016-0361-4 · Cited by 66 · see citing works

PEG length effect of peptide-functional liposome for blood brain barrier (BBB) penetration and brain targeting

Du, Q., Liu, Y., Fan, M., Wei, S., Ismail, M., & Zheng, M. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.06.005 · Cited by 64 · see citing works

Lipocalin 2 regulates iron homeostasis, neuroinflammation, and insulin resistance in the brains of patients with dementia: Evidence from the current literature

Lim, D., Jeong, J., & Song, J. (2021) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13653 · Cited by 61 · see citing works

Neural Mechanisms of Cancer Cachexia

Olson, B. G., Diba, P., Korzun, T., & Marks, D. L. (2021) · Cancers · doi:10.3390/cancers13163990 · Cited by 61 · see citing works

A role for intestinal TLR4-driven inflammatory response during activity-based anorexia

Belmonte, L., Achamrah, N., Nobis, S., Guérin, C., Riou, G., Bôle‐Feysot, C., Boyer, O., Richard, V. J., do-Rego, J.-C., Déchelotte, P., et al. (2016) · Scientific Reports · doi:10.1038/srep35813 · Cited by 59 · see citing works

The role of hypothalamic inflammation, the hypothalamic–pituitary–adrenal axis and serotonin in the cancer anorexia–cachexia syndrome

van Norren, K., Dwarkasing, J. T., & Witkamp, R. F. (2017) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000401 · Cited by 59 · see citing works

Lipid Nanoparticles Elicit Reactogenicity and Sickness Behavior in Mice Via Toll-Like Receptor 4 and Myeloid Differentiation Protein 88 Axis

Korzun, T., Moses, A. S., Jozić, A., Grigoriev, V., Newton, S., Kim, J., Diba, P., Sattler, A. L., Levasseur, P. R., Le, N., et al. (2024) · ACS Nano · doi:10.1021/acsnano.4c05088 · Cited by 58 · see citing works

Melanocortin-4 receptor antagonist TCMCB07 ameliorates cancer- and chronic kidney disease–associated cachexia

Zhu, X., Callahan, M. F., Gruber, K. A., Szumowski, M., & Marks, D. L. (2020) · Journal of Clinical Investigation · doi:10.1172/jci138392 · Cited by 58 · see citing works

Acid‐Responsive Dual‐Targeted Nanoparticles Encapsulated Aspirin Rescue the Immune Activation and Phenotype in Autism Spectrum Disorder

He, X., Xie, J., Zhang, J., Wang, X., Jia, X., Yin, H., Qiu, Z., Yang, Z., Chen, J., Ji, Z., et al. (2022) · Advanced Science · doi:10.1002/advs.202104286 · Cited by 56 · see citing works

Role of Exosomal MicroRNAs and myomiRs in the Development of Cancer Cachexia-Associated Muscle Wasting

Marinho, R., de Alcântara, P. S. M., Otoch, J. P., & Seelaender, M. C. L. (2018) · Frontiers in Nutrition · doi:10.3389/fnut.2017.00069 · Cited by 56 · see citing works

Targeted Nanoparticles with High Heating Efficiency for the Treatment of Endometriosis with Systemically Delivered Magnetic Hyperthermia

Park, Y., Demessie, A. A., Luo, A., Taratula, O. R., Moses, A. S., Do, P., Campos, L., Jahangiri, Y., Wyatt, C. R., Albarqi, H. A., et al. (2022) · Small · doi:10.1002/smll.202107808 · Cited by 51 · see citing works

TRIF is a key inflammatory mediator of acute sickness behavior and cancer cachexia

Burfeind, K. G., Zhu, X., Levasseur, P. R., Michaelis, K. A., Norgard, M. A., & Marks, D. L. (2018) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2018.05.021 · Cited by 46 · see citing works

In vitro and in vivo optimization of liposomal nanoparticles based brain targeted vgf gene therapy

Arora, S., & Singh, J. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.121095 · Cited by 44 · see citing works

Sustained release optimized formulation of anastrozole-loaded chitosan microspheres: in vitro and in vivo evaluation

Shavi, G. V., Nayak, U. Y., Reddy, M. S., Karthik, A., Deshpande, P. B., Kumar, A. R., & Udupa, N. (2011) · Journal of Materials Science Materials in Medicine · doi:10.1007/s10856-011-4274-y · Cited by 37 · see citing works

An Advanced Thermal Decomposition Method to Produce Magnetic Nanoparticles with Ultrahigh Heating Efficiency for Systemic Magnetic Hyperthermia

Demessie, A. A., Park, Y., Singh, P., Moses, A. S., Korzun, T., Sabei, F. Y., Albarqi, H. A., Campos, L., Wyatt, C. R., Farsad, K., et al. (2022) · Small Methods · doi:10.1002/smtd.202200916 · Cited by 36 · see citing works

Poly(caprolactone)-b-poly(ethylene glycol)-Based Polymeric Micelles as Drug Carriers for Efficient Breast Cancer Therapy: A Systematic Review

Shariff, S. H. A., Khodir, W. K. W. A., Hamid, S. A., Haris, M. S., & Ismail, M. W. (2022) · Polymers · doi:10.3390/polym14224847 · Cited by 35 · see citing works

Microglia in the hypothalamus respond to tumor‐derived factors and are protective against cachexia during pancreatic cancer

Burfeind, K. G., Zhu, X., Norgard, M. A., Levasseur, P. R., Huisman, C., Michaelis, K. A., Olson, B. G., & Marks, D. L. (2020) · Glia · doi:10.1002/glia.23796 · Cited by 33 · see citing works

A Comparative Analysis of Orthotopic and Subcutaneous Pancreatic Tumour Models: Tumour Microenvironment and Drug Delivery

Fernandez, J. L., Årbogen, S. B. S., Sadeghinia, M. J., Haram, M., Snipstad, S., TORP, S. H., Einen, C., Mühlenpfordt, M., Maardalen, M., Vikedal, K., et al. (2023) · Cancers · doi:10.3390/cancers15225415 · Cited by 33 · see citing works

Central interleukin-10 attenuates lipopolysaccharide-induced changes in food intake, energy expenditure and hypothalamic Fos expression

Hollis, J. H., Lemus, M. B., Evetts, M. J., & Oldfield, B. J. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.12.016 · Cited by 29 · see citing works

Lipopolysaccharide‐induced hypothalamic inflammation in cancer cachexia‐anorexia is amplified by tumour‐derived prostaglandin E2

Li, X., Holtrop, T., Jansen, F. A. C., Olson, B. G., Levasseur, P. R., Zhu, X., Poland, M., Schalwijk, W., Witkamp, R. F., Marks, D. L., et al. (2022) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13093 · Cited by 25 · see citing works

Phosphorylation of Microglial IRF5 and IRF4 by IRAK4 Regulates Inflammatory Responses to Ischemia

Ngwa, C., Mamun, A. A., Xu, Y., Sharmeen, R., & Liu, F. (2021) · Cells · doi:10.3390/cells10020276 · Cited by 24 · see citing works

Prolactin Attenuates Neuroinflammation in LPS-Activated SIM-A9 Microglial Cells by Inhibiting NF-κB Pathways Via ERK1/2

Jayakumar, P., Martínez-Moreno, C. G., Lorenson, M. Y., Walker, A. M., & Morales, T. (2021) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-021-01087-2 · Cited by 23 · see citing works

Mechanistic Analysis of Drug Release from Theophylline Pellets Coated by Films Containing Pectin, Chitosan and Eudragit® RS

Ghaffari, A., Avadi, M. R., Moghimi, H. R., Oskoui, M., Bayati, K., & Rafiee‐Tehrani, M. (2008) · Drug Development and Industrial Pharmacy · doi:10.1080/03639040701662453 · Cited by 20 · see citing works

Extending dual-targeting upper-limit in liposomal delivery of lithospermic acid B for Alzheimer's mitochondrial revitalization

Meng, R., Yang, X., Li, Y., & Zhang, Q. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.01.059 · Cited by 19 · see citing works

Insights into the mechanism of formation of non-conventional cochleates and its impact on their functional properties

Shuddhodana, S., & Judeh, Z. M. A. (2021) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2021.116249 · Cited by 16 · see citing works

Microgliosis: a double‐edged sword in the control of food intake

Salvi, J., Andreoletti, P., Audinat, É., Balland, É., Fradj, S. B., Cherkaoui‐Malki, M., Heurtaux, T., Liénard, F., Nédélec, E., Rovère, C., et al. (2022) · FEBS Journal · doi:10.1111/febs.16583 · Cited by 12 · see citing works

Targeted Nanocarriers for Systemic Delivery of IRAK4 Inhibitors to Inflamed Tissues

Park, Y., Korzun, T., Moses, A. S., Singh, P., Levasseur, P. R., Demessie, A. A., Sharma, K. S., Morgan, T. K., Raitmayr, C. J., Avila, U., et al. (2023) · Small · doi:10.1002/smll.202306270 · Cited by 9 · see citing works

A Phase 1 Study to Assess Mass Balance and Absolute Bioavailability of Zimlovisertib in Healthy Male Participants Using a 14C‐Microtracer Approach

Singh, R. S. P., Dowty, M. E., Salganik, M. P., Brodfuehrer, J., Walker, G. S., Sharma, R., BEEBE, J. S., & Danto, S. I. (2022) · Clinical Pharmacology in Drug Development · doi:10.1002/cpdd.1109 · Cited by 9 · see citing works

Construction of an intranasal drug delivery system with hypothalamus‐targeting nanoparticles

Rao, Q., Xu, Y., Wang, X., Luo, H., Li, H., Xiong, J., Gao, H., & Cheng, G. (2024) · SusMat · doi:10.1002/sus2.222 · Cited by 9 · see citing works

Glutathione‐Responsive Methotrexate Polymersomes for Potential Management of Ectopic Pregnancy

Mamnoon, B., Moses, A. S., Sundaram, S., Raitmayr, C. J., Morgan, T. K., Baldwin, M. K., Myatt, L., Taratula, O., & Taratula, O. R. (2023) · Small · doi:10.1002/smll.202302969 · Cited by 6 · see citing works

Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Anticancer Phytochemical Delivery: Advances, Challenges, and Future Prospects

Jacob, S., Rao, R., Gorain, B., Boddu, S. H. S., & Nair, A. B. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17081079 · Cited by 81 · see citing works

Targeted Nanoparticles for Drug Delivery Across the Blood–Brain Barrier in Early and Late Stages of Alzheimer's Disease: A Review

Kochman, U., Sitka, H., Kuźniar, J., Czaja, M., Kozubek, P., Beszłej, J. A., & Leszek, J. (2026) · Molecular Neurobiology · doi:10.1007/s12035-025-05417-z · Cited by 60 · see citing works

Targeted drug delivery: designing nanocarriers for improved therapeutic action

Hussain, S., Arif, A., Mujeeb-ur-Rehman, & Shah, M. R. (2026) · Chemical Communications · doi:10.1039/d5cc07306e · Cited by 17 · see citing works

Single-ligand dual-targeting lipid nanoparticles for therapeutic mRNA delivery to glioblastoma across the blood-brain barrier

Goo, Y. T., Cataldi, V., Grigoriev, V., Yadav, N., Korzun, T., Wang, C., Alani, A. W. G., Taratula, O. R., & Taratula, O. (2026) · Journal of Controlled Release · doi:10.1016/j.jconrel.2026.115107 · Cited by 6 · see citing works

Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets

Liu, X., Wang, Z., Zhu, H., Han, Y., & Ji, Q. (2026) · MedComm · doi:10.1002/mco2.70605 · Cited by 5 · see citing works

Resonance Energy Transfer–Driven Photothermal Nanoagent Enables Melanoma Ablation Under Low‐Power Near‐Infrared Irradiation

Singh, P., Raitmayr, C. J., Rizvi, S. Z. H., Salem, A., Grigoriev, V., Korzun, T., Duraisamy, K., Vyawahare, A., Sharma, K. S., Souza, A. P. M., et al. (2026) · Advanced Functional Materials · doi:10.1002/adfm.202522663 · Cited by 3 · see citing works

Nanoparticles as Multifunctional Drug-Delivery Systems: A Comprehensive Review and Integration into Interventional Oncology

Yamada, K., Suzuki, T., & Farsad, K. (2025) · Journal of Vascular and Interventional Radiology · doi:10.1016/j.jvir.2025.08.037 · Cited by 2 · see citing works

Effects of voluntary wheel running on appetite-regulating peptides and neuroinflammation in the hypothalamus of ovariectomized middle-aged mice

Grabowski, M., Grabowska, K., Kostka, M., Pondel, N., Jędrzejowska–Szypułka, H., Małecki, A., Barski, J. J., & Nowacka-Chmielewska, M. M. (2025) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2025.1698306 · Cited by 2 · see citing works

Does Cachexia Matter for Glioblastoma Multiforme?

Kelly, R. M., Henderson, L., & Roy, I. (2026) · Cancers · doi:10.3390/cancers18020333 · Cited by 2 · see citing works

Hypothalamic wars: the last nanodelivery

Fazal, S., Vattathara, J. J., & López, M. (2026) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-026-10022-z · Cited by 1 · see citing works

Chronobiomaterials for circadian-aligned brain therapeutics

Garg, S., Walters, B., & Fernandez, D. C. (2026) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2026.05.005 · Cited by 1 · see citing works

Alzheimer’s Disease and MERC Dysfunction: Integrating Mechanisms, Biomarkers, and Therapeutic Strategies

Kashif, M., & Majumder, D. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-06009-1 · Cited by 1 · see citing works

Nanoparticle-Based Drug Delivery Across the Blood–Brain Barrier: Current In Vivo Evidence, Translational Challenges, and Future Perspectives

Al‐allaq, A. A., Hassan, H. A., Hidayet, H. M., Abdulhakeem, A. A., & Ahmad, Z. A.-A. Q. (2026) · Micro · doi:10.3390/micro6030065 · Cited by 1 · see citing works

Inorganic Electrochemistry Perspectives in Neurobiology

Shahani, Z. (2026) · Royal Society of Chemistry eBooks · doi:10.1039/9781837678945-00094

Biomaterial‐Driven Therapeutic Strategies for the Integrated Management of Obesity

Jiang, Y., Zheng, Y., Jiang, S., Zhang, T., Xie, C., Liu, Y., & Lu, X. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.202505955

Redox-responsive polymeric nanocarriers for targeted delivery of bruceantin to pancreatic cancer

Workie, Y. A., Sharma, K. S., Grigoriev, V., Goo, Y. T., Singh, P., Souza, A. P. M., Duraisamy, K., Vyawahare, A., Raitmayr, C. J., Yadav, N., et al. (2026) · Nanoscale · doi:10.1039/d6nr00636a

Orexin pathway modulation in narcolepsy: from Autoimmune mechanisms to nanotechnology enabled therapeutic delivery

Irfan, M., Shahid, N., Nasar, A., Azmat, M., Khalid, F., & Azam, S. (2026) · Sleep Medicine · doi:10.1016/j.sleep.2026.109253

Research Advances on Organelle-Targeted Drug Delivery Systems for the Treatment of Brain Tumors and Central Nervous System Inflammation

Zhang, M., Chen, B., Li, T., Li, X., Sun, J., Li, Q., Jin, M., Gao, Z., Chen, L., & Huang, W. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18091140

Microglia and neuroinflammation: An in‐depth analysis from functional diversity to disease mechanisms

Chen, J., Zhang, W., Song, L., Liao, Y., Zhang, H., Xia, Y., & Cui, D. (2026) · Clinical and Translational Medicine · doi:10.1002/ctm2.70839

Engineering Mosaic T7 Bacteriophages for Dual Peptide Display to Enable Cellular Targeting and Ligand‐Directed Protein Capture

Marchetti, L., Põšnograjeva, K., Lingasamy, P., Pleiko, K., Ilves, I., & Teesalu, T. (2026) · Biotechnology Journal · doi:10.1002/biot.70322

Neuropeptide signaling in perioperative neurocognitive disorders: Receptor biology, mechanistic links, and a cautious prevention framework

Chen, L., & Gao, Y. (2026) · Neuropeptides · doi:10.1016/j.npep.2026.102667

Targeted nanocarriers for microglia-selective cytochalasin D delivery to modulate neuroinflammation after acute brain injuriesPreprint

Sahnoun, S. E. M., Noristani, R., Alimonti, P., Pes, J., Gubeljak, L., Ilyas, S., Arik, E., Florea, A., Buhl, E. M., Neumaier, B., et al. (2025) · doi:10.22541/au.176349281.18872463/v1

Tanycyte-mediated uptake and transport of PCL nanoparticles in the hypothalamus

Sun, Z., Zhang, L., Xu, J., Zheng, X., Jiang, M., Jiang, S., Wang, X., & Li, J. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.152974

ANP-GBSA@CHI/TA: A Gut-Targeted Nanomedicine for Attenuating Neuroinflammation and Cognitive Dysfunction

Fan, J., Huang, J., Jiang, S., Wu, J., Wang, Z., Tang, Y., Zhao, G., & Zhao, M. (2026) · ACS Applied Nano Materials · doi:10.1021/acsanm.5c04030

Multifunctional theranostic nanocarrier platform for microglia-selective cytochalasin D delivery to modulate neuroinflammation after acute brain injuries

Sahnoun, S. E. M., Noristani, R., Alimonti, P., Pes, J., Gubeljak, L., Szymura, A., Ilyas, S., Arik, E., Florea, A., Buhl, E. M., et al. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124495 · Cited by 1 · see citing works

Targeting microglia-mediated neuroinflammation via pH-responsive lipid nanoparticle delivery of HDAC inhibitor RGFP966 in ischemic stroke

Liu, Y., Luo, B., Xu, Y., Liu, D., & Wang, Q.-X. (2026) · Science and Technology of Advanced Materials · doi:10.1080/14686996.2026.2699624 · Cited by 1 · see citing works