The DOI matches its Crossref record; 48 of the 49 references it cites were found in a registry or an index.
Using Graphene Oxide High Near‐Infrared Absorbance for Photothermal Treatment of Alzheimer's Disease
Abstract
A novel strategy to dissociate amyloid aggregation is presented, using localised heat generation from a clinically used amyloid staining dye, thioflavin-S (ThS)-modified graphene oxide (GO) under NIR laser irradiation. Compared to traditional chemotherapies, photothermal therapy shows reduced side effects and improved selectivity and safety.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The second approach—external stimulus-triggered mode switching—employs graphene oxide functionalized with thioflavin-S (ThS).”
From Theranostic Nanoplatforms for Alzheimer's Disease: A Critical Analysis of Conceptual Contradictions (2026) · cites this paper as [30]
In the citing paper
“Continuous diagnostics enable real-time efficacy monitoring while minimizing systemic toxicity [30].”
From Theranostic Nanoplatforms for Alzheimer's Disease: A Critical Analysis of Conceptual Contradictions (2026) · cites this paper as [30]
In the citing paper
“ThS specifically binds amyloid fibrils and fluoresces, providing continuous diagnostic signaling.”
From Theranostic Nanoplatforms for Alzheimer's Disease: A Critical Analysis of Conceptual Contradictions (2026) · cites this paper as [30]
In the citing paper
“Therapeutic action activates via near-infrared (NIR) irradiation: graphene oxide absorbs NIR light, generating localized heat to disassemble fibrils.”
From Theranostic Nanoplatforms for Alzheimer's Disease: A Critical Analysis of Conceptual Contradictions (2026) · cites this paper as [30]
Citations
Cites
Preparation of Graphitic Oxide
Hummers, W. S., & Offeman, R. E. (1958) · Journal of the American Chemical Society · doi:10.1021/ja01539a017 · Cited by 30,194
Alzheimer's Disease: Genes, Proteins, and Therapy
Selkoe, D. J. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.741 · Cited by 6,063
Preparation and characterization of graphene oxide paper
Dikin, D. A., Stankovich, S., Zimney, E. J., Piner, R. D., Dommett, G., Evmenenko, G., Nguyen, S. T., & Ruoff, R. S. (2007) · Nature · doi:10.1038/nature06016 · Cited by 5,616
Chemically Derived, Ultrasmooth Graphene Nanoribbon Semiconductors
Li, X., Wang, X., Zhang, L., Lee, S., & Dai, H. (2008) · Science · doi:10.1126/science.1150878 · Cited by 4,807
Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
Hirsch, L. R., Stafford, R. J., Bankson, J. A., Sershen, S. R., Rivera, B., Price, R. E., Hazle, J. D., Halas, N. J., & West, J. L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2232479100 · Cited by 3,961
PEGylated Nanographene Oxide for Delivery of Water-Insoluble Cancer Drugs
Liu, Z., Robinson, J. T., Sun, X., & Dai, H. (2008) · Journal of the American Chemical Society · doi:10.1021/ja803688x · Cited by 3,603
Nano-graphene oxide for cellular imaging and drug delivery
Sun, X., Liu, Z., Welsher, K., Robinson, J. T., Goodwin, A. P., Zaric, S., & Dai, H. (2008) · Nano Research · doi:10.1007/s12274-008-8021-8 · Cited by 3,318
Kovtyukhova, N. I., Ollivier, P. J., Martin, B. R., Mallouk, T. E., Чижик, С. А., Buzaneva, E. V., & Gorchinskiy, A. (1999) · Chemistry of Materials · doi:10.1021/cm981085u · Cited by 3,247
Blennow, K., de Leon, M. J., & Zetterberg, H. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69113-7 · Cited by 3,134
Graphene in Mice: Ultrahigh In Vivo Tumor Uptake and Efficient Photothermal Therapy
Yang, K., Zhang, S., Zhang, G., Sun, X., Lee, S., & Liu, Z. (2010) · Nano Letters · doi:10.1021/nl100996u · Cited by 2,411
Flagged first, then by citations
1 of the 49 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- Liu Y., 2011, Chem. Soc. Rev.
- Li M., Chem. Sci.
Cited by
Sorted by citations
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
Huang, Y., Ren, J., & Qu, X. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00672 · Cited by 3,581
Self-citationFunctional Nanomaterials for Phototherapies of Cancer
Cheng, L., Wang, C., Feng, L., Yang, K., & Liu, Z. (2014) · Chemical Reviews · doi:10.1021/cr400532z · Cited by 2,438
Carbon Nanomaterials for Biological Imaging and Nanomedicinal Therapy
Hong, G., Diao, S., Antaris, A. L., & Dai, H. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00008 · Cited by 1,403
Ultrasmall Black Phosphorus Quantum Dots: Synthesis and Use as Photothermal Agents
Sun, Z., Xie, H., Tang, S., Yu, X., Guo, Z., Shao, J., Zhang, H., Huang, H., Wang, H., & Chu, P. K.-H. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201506154 · Cited by 1,137
Biodegradable black phosphorus-based nanospheres for in vivo photothermal cancer therapy
Shao, J., Xie, H., Huang, H., Li, Z., Sun, Z., Xu, Y., Xiao, Q., Yu, X., Zhao, Y., Zhang, H., et al. (2016) · Nature Communications · doi:10.1038/ncomms12967 · Cited by 1,012
Metadata
- Authors
- Li, M., Yang, X., Ren, J., Qu, K., & Qu, X.
- Affiliations
- Chinese Academy of Sciences (CN)
- Corresponding author
- Qu, Xiaogang
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2012-03-07
- Volume
- 24
- Issue
- 13
- Pages
- 1722-1728
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2005626048
- Cited by
- 535
- References
- 49
- Citations by year
- 2026: 6 · 2025: 15 · 2024: 19 · 2023: 34 · 2022: 37 · 2021: 41 · 2020: 49 · 2019: 49 · 2018: 57 · 2017: 58 · 2016: 45 · 2015: 39 · 2014: 45 · 2013: 37 · 2012: 4
- FWCI
- 22.76
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Advanced Materials (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Physical Sciences › Engineering › Biomedical Engineering › Graphene and Nanomaterials Applications
- Keywords
- graphene oxide, near-infrared photothermal therapy, Alzheimer's disease, amyloid fibril formation, thioflavin S, NIR laser irradiation, amyloid plaques
- MeSH terms
- Alzheimer Disease, Amyloid, Animals, Cell Survival, Graphite, Humans, Hyperthermia, Induced, Oxides, Phototherapy, Thiazoles, PC12 Cells, Nanostructures, Mice, Rats, Benzothiazoles
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review