The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
Conferring Ti‐Based MOFs with Defects for Enhanced Sonodynamic Cancer Therapy
Abstract
The development of highly efficient, multifunctional, and biocompatible sonosensitizer is still a priority for current sonodynamic therapy (SDT). Herein, a defect‐rich Ti‐based metal–organic framework (MOF) (D‐MOF(Ti)) with greatly improved sonosensitizing effect is simply constructed and used for enhanced SDT. Compared with the commonly used sonosensitizer TiO 2, D‐MOF(Ti) results in a superior reactive oxygen species (ROS) yield under ultrasound (US) irradiation due to its narrow bandgap, which principally improves the US‐triggered electron–hole separation. Meanwhile, due to the existence of Ti 3+ ions, D‐MOF(Ti) also exhibits a high level of Fenton‐like activity to enable chemodynamic therapy. Particularly, US as the excitation source of SDT can simultaneously enhance the Fenton‐like reaction to achieve remarkably synergistic outcomes for oncotherapy. More importantly, D‐MOF(Ti) can be degraded and metabolized out of the body after completion of its therapeutic functions without off‐target toxicity. Overall, this work identifies a novel Ti‐familial sonosensitizer harboring great potential for synergistic sonodynamic and chemodynamic cancer therapy.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Nanoparticles in Photodynamic Therapy
Lucky, S. S., Soo, K. C., & Zhang, Y. (2015) · Chemical Reviews · doi:10.1021/cr5004198 · Cited by 2,980
Functional Nanomaterials for Phototherapies of Cancer
Cheng, L., Wang, C., Feng, L., Yang, K., & Liu, Z. (2014) · Chemical Reviews · doi:10.1021/cr400532z · Cited by 2,425
Metal–organic frameworks for artificial photosynthesis and photocatalysis
Zhang, T., & Lin, W. (2014) · Chem. Soc. Rev. · doi:10.1039/c4cs00103f · Cited by 2,163
Chemodynamic Therapy: Tumour Microenvironment‐Mediated Fenton and Fenton‐like Reactions
Tang, Z., Liu, Y., He, M., & Bu, W. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201805664 · Cited by 1,951
Nanotechnology for Multimodal Synergistic Cancer Therapy
Fan, W., Yung, B., Huang, P., & Chen, X. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00258 · Cited by 1,791
Photocatalytic organic pollutants degradation in metal–organic frameworks
Wang, C.-C., Li, J.-R., Lv, X.-L., Zhang, Y.-Q., & Guo, G. (2014) · Energy Environ. Sci. · doi:10.1039/c4ee01299b · Cited by 1,671
Lin, L., Song, J., Song, L., Ke, K., Liu, Y., Zhou, Z., Shen, Z., Li, J., Yang, Z., Tang, W., et al. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201712027 · Cited by 1,466
Tumor-selective catalytic nanomedicine by nanocatalyst delivery
Huo, M., Wang, L., Chen, Y., & Shi, J. (2017) · Nature Communications · doi:10.1038/s41467-017-00424-8 · Cited by 1,322
Qian, X., Zheng, Y., & Chen, Y. (2016) · Advanced Materials · doi:10.1002/adma.201602012 · Cited by 882
Wang, D., Huang, R., Liu, W., Sun, D., & Li, Z. (2014) · ACS Catalysis · doi:10.1021/cs501169t · Cited by 869
Cited by
Zhou, Y., Fan, S., Feng, L., Huang, X., & Chen, X. (2021) · Advanced Materials · doi:10.1002/adma.202104223 · Cited by 463
Nanoscale covalent organic frameworks: from controlled synthesis to cancer therapy
He, X., Jiang, Z., Akakuru, O. U., Li, J., & Wu, A. (2021) · Chemical Communications · doi:10.1039/d1cc04846e · Cited by 303
Recent Developments of Inorganic Nanosensitizers for Sonodynamic Therapy
He, Z., Du, J., Miao, Y., & Li, Y. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202300234 · Cited by 105
Nano-ROS-generating approaches to cancer dynamic therapy: Lessons from nanoparticles
Zhang, Q., Luo, Q., Liu, Z., Sun, M., & Dong, X. (2023) · Chemical Engineering Journal · doi:10.1016/j.cej.2022.141225 · Cited by 94
Luo, J., Cao, J., Ma, G., Wang, X., Sun, Y., Zhang, C., Shi, Z., Zeng, Y., Zhang, T., & Huang, P. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c08951 · Cited by 47
Metadata
- Authors
- Liang, S., Xiao, X., Bai, L., Liu, B., Yuan, M., Ma, P., Pang, M., Cheng, Z., & Lin, J.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2021-04
- Volume
- 33
- Issue
- 18
- Pages
- e2100333-e2100333
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W3148405623
- Cited by
- 359
- References
- 52
- FWCI
- 17.85
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Conferring Ti‐Based MOFs with Defects for Enhanced Sonodynamic Cancer Therapy. https://app.cochat.ai/papers/10.1002/adma.202100333
- The paper
- Liang, S., Xiao, X., Bai, L., Liu, B., Yuan, M., Ma, P., Pang, M., Cheng, Z., & Lin, J. (2021). Conferring Ti‐Based MOFs with Defects for Enhanced Sonodynamic Cancer Therapy. Advanced Materials. https://doi.org/10.1002/adma.202100333
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
