Cited by 187Advanced Sensor and Energy Harvesting MaterialsNon-Invasive Vital Sign MonitoringAdvancements in Transdermal Drug Delivery

Recent Advances in Intelligent Wearable Medical Devices Integrating Biosensing and Drug Delivery

Tan, Minhong, Xu, Yang, Gao, Ziqi, Yuan, Tiejun, Liu, Qingjun, Yang, Rusen, Zhang, Bin, Peng, Lihua·2022·Advanced Materials

Abstract

The primary roles of precision medicine are to perform real‐time examination, administer on‐demand medication, and apply instruments continuously. However, most current therapeutic systems implement these processes separately, leading to treatment interruption and limited recovery in patients. Personalized healthcare and smart medical treatment have greatly promoted research on and development of biosensing and drug‐delivery integrated systems, with intelligent wearable medical devices (IWMDs) as typical systems, which have received increasing attention because of their non‐invasive and customizable nature. Here, the latest progress in research on IWMDs is reviewed, including their mechanisms of integrating biosensing and on‐demand drug delivery. The current challenges and future development directions of IWMDs are also discussed.

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Crossref · 10.1002/adma.202108491

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  • Intelligent wearable medical devices (IWMDs) facilitate real-time monitoring, diagnosis, and treatment of various medical conditions.

    “With the introduction of flexible electronics, the development of intelligent wearable medical devices (IWMDs) has become a reality, facilitating real-time monitoring, diagnosis, and treatment of various medical conditions (Tan et al. 2022).”
  • IWMDs provide predictive bio-analysis, timely treatment intervention, and improved drug efficacy, thereby promoting precision medicine.

    “Through tracking physiological and pathological factors and delivering therapeutic agents acting in an on-demand manner, IWMDs have become indispensable in providing predictive bio-analysis, timely treatment intervention, and improved drug efficacy, thereby promoting precision medicine (cheol Jeong et al. 2018; Tan et al. 2022).”

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References 260 · Cited by 187

Authors
Tan, M., Xu, Y., Gao, Z., Yuan, T., Liu, Q., Yang, R., Zhang, B., & Peng, L.
Affiliations
  • Zhejiang University (CN)
  • Xidian University (CN)
  • Macau University of Science and Technology (MO)
Corresponding author
Peng, Lihua
Venue
Advanced Materials
Publisher
Wiley
Published
2022-04-28
Volume
34
Issue
27
Pages
e2108491-e2108491
ISSN
  • 0935-9648 (ISSN-L)
  • 1521-4095
OpenAlex
W4205969521
Cited by
187
References
260
Citations by year
2026: 36 · 2025: 50 · 2024: 46 · 2023: 43 · 2022: 12
FWCI
3.37
Type
journal article
Language
en
Open access
closed
Locations
  • Advanced Materials (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Key Research and Development Program of China (2018YFC1105404)
  • National Natural Science Foundation of China (81473145)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
  • Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
Keywords
biosensing, on-demand drug delivery, precision medicine, personalized healthcare, non-invasive monitoring, continuous monitoring
MeSH terms
Wearable Electronic Devices, Pharmaceutical Preparations, Humans, Biosensing Techniques, Precision Medicine

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