The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Fragile X and autism: A multicenter survey
Abstract
We screented 183 autistic males for the fra(X) and found 24 (13.1%) to be positive. Adding the subjects of this study to those of 11 other surveys, of which 6 were positive and 5 were negative, a total of 614 autistis males have been screened. Overall 47 (7.7%) were positive. Based on this estimate and the prevalence of autism and fra(X), we estimate that 12.3% of fra(X) males are autistic. We have found that 17.3% of our fra(X) males were autistic and overall a 21.2% frequency has been reported, these higher figures are most likely due to biases in age and ascertainment. With an overall 7.7% frequency of fra(X) among autistic males and an estimated 12.3% of autism among fra(X) males, we conclude there is likely to be a significant association of fra(X) with autism. Because fra(X) appears to be the single most common cause of the condition, chromosomal testing is recommended for any autistic person with undiagnosed etiology.
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Citations
Cites
Adult fragile X syndrome: Clinico-neuropathologic findings
Rudelli, R. D., Brown, W. T., Wisniewski, K., Jenkins, E. C., Laure-Kamionowska, M., Connell, F., & Wisniewski, H. M. (1985) · Acta Neuropathologica · doi:10.1007/bf00687814 · Cited by 362
Self-citationAn analysis of autism in fifty males with the fragile X syndrome
Hagerman, R. J., Jackson, A. W., Levitas, A., Rimland, B., Braden, M., Opitz, J. M., & Reynolds, J. F. (1986) · American Journal of Medical Genetics · doi:10.1002/ajmg.1320230128 · Cited by 238
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Autism and the pervasive developmental disorders
Volkmar, F. R., & Klin, A. (2012) · New Oxford Textbook of Psychiatry · doi:10.1093/med/9780199696758.003.0214 · Cited by 939
Autism Profiles of Males With Fragile X Syndrome
Harris, S. W., Hessl, D., Goodlin-Jones, B., Ferranti, J., Bacalman, S., Barbato, I., Tassone, F., Hagerman, P. J., Herman, K., & Hagerman, R. J. (2008) · American Journal on Mental Retardation · doi:10.1352/2008.113:427-438 · Cited by 396
Moss, J., & Howlin, P. (2009) · Journal of Intellectual Disability Research · doi:10.1111/j.1365-2788.2009.01197.x · Cited by 310
Geschwind, D. H., Sowinski, J., Lord, C., Iversen, P., Shestack, J., Jones, P., Ducat, L., & Spence, S. J. (2001) · The American Journal of Human Genetics · doi:10.1086/321292 · Cited by 302
Nishimura, Y., Martin, C. L., Vazquez-Lopez, A., Spence, S. J., Alvarez-Retuerto, A. I., Sigman, M., Steindler, C., Pellegrini, S., Schanen, N. C., Warren, S. T., et al. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm116 · Cited by 276
Metadata
- Authors
- Brown, W. T., Jenkins, E. C., Cohen, I. L., Fisch, G. S., Wolf‐Schein, E. G., Gross, A., Waterhouse, L., Fein, D., Mason‐Brothers, A., Ritvo, E., Ruttenberg, B. A., Bentley, W., Castells, S., Opitz, J. M., & Reynolds, J. F.
- Venue
- American Journal of Medical Genetics
- Publisher
- Wiley
- Published
- 1986-01
- Volume
- 23
- Issue
- 1-2
- Pages
- 341-352
- ISSN
- 0148-7299 (ISSN-L)
- 1096-8628
- OpenAlex
- W2002964351
- Cited by
- 180
- References
- 2
- FWCI
- 11.03
- Type
- journal article
- Language
- en
- Open access
- closed
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- Brown, W. T., Jenkins, E. C., Cohen, I. L., Fisch, G. S., Wolf‐Schein, E. G., Gross, A., Waterhouse, L., Fein, D., Mason‐Brothers, A., Ritvo, E., Ruttenberg, B. A., Bentley, W., Castells, S., Opitz, J. M., & Reynolds, J. F. (1986). Fragile X and autism: A multicenter survey. American Journal of Medical Genetics. https://doi.org/10.1002/ajmg.1320230126
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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