Cited by 22Dementia and Cognitive Impairment ResearchHealth Systems, Economic Evaluations, Quality of LifeGeriatric Care and Nursing Homes

Cost effectiveness of non‐drug interventions that reduce nursing home admissions for people living with dementia

Open access
Jutkowitz, Eric, Pizzi, Laura T., Shewmaker, Peter, Alarid‐Escudero, Fernando, Epstein‐Lubow, Gary, Prioli, Katherine M., Gaugler, Joseph E., Gitlin, Laura N.·2023·Alzheimer's & Dementia

Abstract

INTRODUCTION: Six million Americans live with Alzheimer's disease and Alzheimer's disease and related dementias (AD/ADRD), a major health‐care cost driver. We evaluated the cost effectiveness of non‐pharmacologic interventions that reduce nursing home admissions for people living with AD/ADRD. METHODS: We used a person‐level microsimulation to model the hazard ratios (HR) on nursing home admission for four evidence‐based interventions compared to usual care: Maximizing Independence at Home (MIND), NYU Caregiver (NYU); Alzheimer's and Dementia Care (ADC); and Adult Day Service Plus (ADS Plus). We evaluated societal costs, quality‐adjusted life years and incremental cost‐effectiveness ratios. RESULTS: All four interventions cost less and are more effective (i.e., cost savings) than usual care from a societal perspective. Results did not materially change in 1‐way, 2‐way, structural, and probabilistic sensitivity analyses. CONCLUSION: Dementia‐care interventions that reduce nursing home admissions save societal costs compared to usual care. Policies should incentivize providers and health systems to implement non‐pharmacologic interventions.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1002/alz.12964

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Individual studies of care coordination have shown reduced care home admission and cost-effectiveness from a societal and individual perspective, but a meta-analysis of 14 care coordination RCTs did not show a statistically significant reduction in care home admission or hospitalisation.

    “Individual studies of care coordination have shown reduced care home admission, and cost-effectiveness from a societal and individual perspective,(479) but a meta-analysis of 14 care coordination RCTs did not show a statistically significant reduction in care home admission or hospitalisation. (478)”

    From Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission (2024) · cites this paper as [479]

    Split into 2 atoms — 1 confirmed, 0 partially supported, 0 disputed, 0 misattributed, 1 unverifiable. Expand the claim to see per-atom verdicts.

    Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 48

  1. [1]2021 Alzheimer’s disease facts and figures. Alzheimers Dement. 2021; 17(3): 327– 406. 33756057
  2. [2]Hurd MD, Martorell P, Delavande A, Monetary costs of dementia in the United States. N Engl J Med. 2013; 368(14): 1326– 1334. 23550670 PMC3959992
  3. [3]Jutkowitz E, Kane RL, Gaugler JE, Societal and family lifetime cost of dementia: implications for policy. J Am Geriatr Soc. 2017; 65(10): 2169– 2175. 28815557 PMC5657516
  4. [4]Committee on Family Caregiving for Older Adults; Board on Health Care Services; Health and Medicine Division; National Academies of Sciences, Engineering, and Medicine. Families Caring for an Aging America. Schulz R, Eden J, eds. National Academies Press (US); 2016. 27905704
  5. [5]Wiles JL, Leibing A, Guberman N, The meaning of “aging in place” to older people. Gerontologist. 2012; 52(3): 357– 366. 21983126
  6. [6]Robison J, Porter M, Shugrue N, Connecticut’s “Money follows the person” yields positive results for transitioning people out of institutions. Health Aff (Millwood). 2015; 34(10): 1628– 1636. 26438737
  7. [9]Jutkowitz E, Gaugler JE, Trivedi AN, Family caregiving in the community up to 8-years after onset of dementia. BMC Geriatr. 2020; 20(1): 216. 32560701 PMC7304188
  8. [10]Livingston G, Sommerlad A, Orgeta V, Dementia prevention, intervention, and care. Lancet. 2017; 390(10113): 2673– 2734. 28735855
  9. [12]Wolff JL, Spillman BC, Freedman VA, A national profile of family and unpaid caregivers who assist older adults with health care activities. JAMA Intern Med. 2016; 176(3): 372– 379. 26882031 PMC4802361
  10. [13]Samus Q, Johnston D, Black B, A multidimensional home-based care coordination intervention for elders with memory disorders: the Maximizing Independence at Home (MIND) pilot randomized trial. Am J Geriatr Psychiatry. 2014; 22(4): 398– 414. 24502822 PMC4034346
  11. [14]Gitlin LN, Reever K, Dennis MP, Enhancing quality of life of families who use adult day services: short- and long-term effects of the adult day services plus program. Gerontologist. 2006; 46(5): 630– 639. 17050754
  12. [15]Gaugler JE, Roth DL, Haley WE, Can counseling and support reduce burden and depressive symptoms in caregivers of people with Alzheimer’s disease during the transition to institutionalization? Results from the New York University caregiver intervention study. J Am Geriatr Soc. 2008; 56(3): 421– 428. 18179495 PMC2700042
  13. [16]Jennings LA, Laffan AM, Schlissel AC, Health care utilization and cost outcomes of a comprehensive dementia care program for medicare beneficiaries. JAMA Intern Med. 2019; 179(2): 161– 166. 30575846 PMC6439653
  14. [17]Van’t Leven N, Prick AEJC, Groenewoud JG, Dyadic interventions for community-dwelling people with dementia and their family caregivers: a systematic review. Int Psychogeriatr. 2013; 25(10): 1581– 1603. 23883489
  15. [18]Hansen RA, Gartlehner G, Webb AP, Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer’s disease: a systematic review and meta-analysis. Clin Interv Aging. 2008; 3(2): 211– 225. 18686744 PMC2546466
  16. [19]Maust DT, Kim HM, Seyfried LS, Antipsychotics, other psychotropics, and the risk of death in patients with dementia: number needed to harm. JAMA Psychiatry. 2015; 72(5): 438– 445. 25786075 PMC4439579
  17. [22]Moore A, Patterson C, Lee L, Fourth Canadian Consensus Conference on the diagnosis and treatment of dementia: recommendations for family physicians. Can Fam Physician. 2014; 60(5): 433– 438. 24829003 PMC4020644
  18. [23]Gitlin LN, Kales HC, Lyketsos CG. Nonpharmacologic management of behavioral symptoms in dementia. JAMA. 2012; 308(19): 2020– 2029. 23168825 PMC3711645
  19. [24]Lyketsos CG, Colenda CC, Beck C, Position statement of the American Association for geriatric psychiatry regarding principles of care for patients with dementia resulting from Alzheimer disease. Am J Geriatr Psychiatry. 2006; 14(7): 561– 572. 16816009
  20. [26]Callahan CM, Sachs GA, Lamantia MA, Unroe KT, Arling G, Boustani MA. Redesigning systems of care for older adults with Alzheimer’s disease. Health Aff (Millwood). 2014; 33(4): 626– 632. 24711324 PMC5337406
  21. [27]Lees Haggerty K, Epstein-Lubow G, Spragens LH, Recommendations to improve payment policies for comprehensive dementia care. J Am Geriatr Soc. 2020; 68(11): 2478– 2485. 32975812
  22. [28]Boustani M, Alder CA, Solid CA, Reuben D. An alternative payment model to support widespread use of collaborative dementia care models. Health Aff Millwood. 2019; 38(1): 54– 59. 30615525
  23. [29]Hodgson N, Gitlin LN. Implementing and sustaining family care programs in real-world settings: Barriers and facilitators. In: Gaugler J, ed. Bridging the Family Care Gap. Elsevier; 2021: 179– 219.
  24. [31]Chrysanthopoulou SA, Rutter CM, Gatsonis CA. Bayesian versus Empirical Calibration of Microsimulation Models: a comparative analysis. Med Decis Making. 2021; 41(6): 714– 726. 33966518 PMC9294658
  25. [32]Shewmaker P, Chrysanthopoulou SA, Iskandar R, Microsimulation Model Calibration with Approximate Bayesian Computation in R: a tutorial. Med Decis Making. 2022; 42(5): 557– 570. 35311401 PMC9198004
  26. [33]Tanner JA, Black BS, Johnston D, A randomized controlled trial of a community-based dementia care coordination intervention: effects of MIND at Home on caregiver outcomes. Am J Geriatr Psychiatry. 2015; 23(4): 391– 402. 25260557 PMC4355038
  27. [34]Mittelman MS, Haley WE, Clay OJ, Roth DL. Improving caregiver well-being delays nursing home placement of patients with Alzheimer disease. Neurology. 2006; 67(9): 1592– 1599. 17101889
  28. [35]Gaugler JE, Reese M, Mittelman MS. Effects of the NYU caregiver intervention-adult child on residential care placement. Gerontologist. 2013; 53: 985– 997. 23339050 PMC3826164
  29. [36]Foldes SS, Moriarty JP, Farseth PH, Mittelman MS, Long KH. Medicaid savings from The New York University Caregiver Intervention for families with dementia. The Gerontologist. 2018; 58(2): e97– e106. 29106531
  30. [37]Neumann PJ, Hermann RC, Kuntz KM, Cost-effectiveness of donepezil in the treatment of mild or moderate Alzheimer’s disease. Neurology. 1999; 52(6): 1138– 1145. 10214734
  31. [38]MetLife Mature Market Institute. Market Survey of Long-Term Care Costs: The 2012 MetLife Market Survey of Nursing Home, Assisted Living, Adult Day Services, and Home Care Costs. MetLife Mature Market Institute; 2012: 1– 51. https://www.carolinafep.com/library/mmi2012-market-survey-long-term-care-costs.pdf
  32. [39]Chari AV, Engberg J, Ray KN, Mehrotra A. The opportunity costs of informal elder-care in the United States: new estimates from the American Time Use Survey. Health Serv Res. 2015; 50(3): 871– 882. 25294306 PMC4450934
  33. [40]Sculpher MJ, Basu A, Kuntz KM, Meltzer DO. Reflecting uncertainty in cost-effectiveness analysis. In: Neumann PJ, Ganiats TG, Russell LB, Sanders GD, Siegel JE, eds. Cost-Effectiveness in Health and Medicine. Oxford University Press; 2016.
  34. [41]Neumann PJ, Sanders GD, Russell LB, Siegel JE, Ganiats TG. Cost-Effectiveness in Health and Medicine. Oxford University Press; 2016.
  35. [42]Turner RM, Spiegelhalter DJ, Smith GCS, Thompson SG. Bias modelling in evidence synthesis. J R Stat Soc Ser A Stat Soc. 2009; 172(1): 21– 47. PMC2667303 19381328
  36. [43]Jalal H, Pechlivanoglou P, Krijkamp E, Alarid-Escudero F, Enns E, Hunink MGM. An overview of R in health decision sciences. Med Decis Making. 2017; 37(7): 735– 746. 28061043 PMC12185038
  37. [44]Krijkamp EM, Alarid-Escudero F, Enns EA, Jalal HJ, Hunink MGM, Pechlivanoglou P. Microsimulation modeling for health decision sciences using R: a tutorial. Med Decis Making. 2018; 38(3): 400– 422. 29587047 PMC6349385
  38. [46]Chen C, Zissimopoulos JM. Racial and ethnic differences in trends in dementia prevalence and risk factors in the United States. Alzheimers Dement Transl Res Clin Interv. 2018; 4: 510– 520. PMC6197734 30364652
  39. [47]Gitlin L, Maslow K, National Research Summit on Care, Services and Supports for Persons with Dementia and Their Caregivers. 2018. Accessed November 4, 2021. https://aspe.hhs.gov/sites/default/files/migrated_legacy_files//181216/FinalReport.pdf 31784409
  40. [48]Gitlin LN, Baier RR, Jutkowitz E, Dissemination and implementation of evidence-based dementia care using embedded pragmatic trials. J Am Geriatr Soc. 2020; 68(S2): S28– S36. 32589277 PMC7470172
  41. [49]Ito K, Chapman R, Pearson SD, Tafazzoli A, Yaffe K, Gurwitz JH. Evaluation of the cost-effectiveness of drug treatment for Alzheimer disease in a simulation model that includes caregiver and societal factors. JAMA Netw Open. 2021; 4(10): e2129392. 34677596 PMC8536950
  42. [50]Jutkowitz E, MacLehose RF, Gaugler JE, Dowd B, Kuntz KM, Kane RL. Risk factors associated with cognitive, functional, and behavioral trajectories of newly diagnosed dementia patients. J Gerontol A Biol Sci Med Sci. 2017; 72(2): 251– 258. 27129917 PMC5344797
  43. [51]Jutkowitz E, Kuntz KM, Dowd B, Gaugler JE, MacLehose RF, Kane RL. Effects of cognition, function, and behavioral and psychological symptoms on out-of-pocket medical and nursing home expenditures and time spent caregiving for persons with dementia. Alzheimers Dement. 2017; 13(7): 801– 809. 28161279 PMC5644025
  44. [52]Jutkowitz E, Kane RL, Dowd B, Gaugler JE, MacLehose RF, Kuntz KM, Effects of Cognition, Function, and Behavioral and Psychological Symptoms on Medicare Expenditures and Health Care Utilization for Persons With Dementia. J Gerontol: Ser A, 2017; 72(6), 818– 824. PMC6075208 28369209
  45. [53]Solomon TM, deBrosGB,Budson AE,Mirkovic N,MurphyCA,Solomon PR. Correlational analysis of 5 commonly used measures of cognitive functioning and mental status: an update. Am J Alzheimers Dis Other Demen. 2014; 29(8): 718– 722. 24829061 PMC10852956
  46. [54]Intrator O, Hiris J, Berg K, Miller SC, Mor V. The residential history file: studying nursing home residents’ long-term care histories (*). Health Serv Res. 2011 Feb; 46(1 Pt 1): 120– 37. doi: 10.1111/j.1475-6773.2010.01194.x 21029090 PMC3015013 · DOI
  47. [56]Bharmal MF, Dedhiya S, Craig BA, Incremental dementiarelatedexpenditures in a Medicaid population. Am J Geriatr Psychiatry 2012; 20: 73– 83. 22183012
  48. [57]Mayeda ER, Glymour MM, Quesenberry CP, Johnson JK, Pérez-Stable EJ, Whitmer RA. Survival after dementia diagnosis in five racial/ethnic groups. Alzheimers Dement. 2017 Jul; 13(7): 761– 769. doi: 10.1016/j.jalz.2016.12.008 28174069 PMC5496783 · DOI

Cited by

Sorted by citations

Authors
Jutkowitz, E., Pizzi, L. T., Shewmaker, P., Alarid‐Escudero, F., Epstein‐Lubow, G., Prioli, K. M., Gaugler, J. E., & Gitlin, L. N.
Affiliations
  • Brown University (US)
  • Rutgers, The State University of New Jersey (US)
  • Stanford University (US)
  • Department of Health Services, Policy & Practice Brown University School of Public Health Providence Rhode Island USA
  • University of Minnesota (US)
  • Drexel University (US)
Corresponding author
Jutkowitz, Eric
Venue
Alzheimer's & Dementia
Publisher
Wiley
Published
2023-04-06
Volume
19
Issue
9
Pages
3867-3893
ISSN
  • 1552-5260 (ISSN-L)
  • 1552-5279
OpenAlex
W4362657255
Cited by
22
References
3
Citations by year
2026: 6 · 2025: 11 · 2024: 3 · 2023: 2
FWCI
4.48
Type
journal article
Language
en
Open access
Locations
  • Alzheimer s & Dementia (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute on Aging (1R21AG059623‐01, 1R01AG060871‐01, 1RF1AG069771, R01 AG049692)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
  • Health Sciences › Health Professions › General Health Professions › Geriatric Care and Nursing Homes
Keywords
dementia, Alzheimer's disease and related dementias
MeSH terms
Cost-Effectiveness Analysis, Adult, Alzheimer Disease, Cost-Benefit Analysis, Humans, Nursing Homes, Caregivers

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review