Cost effectiveness of non‐drug interventions that reduce nursing home admissions for people living with dementia
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INTRODUCTION: Six million Americans live with Alzheimer's disease and Alzheimer's disease and related dementias (AD/ADRD), a major health‐care cost driver. We evaluated the cost effectiveness of non‐pharmacologic interventions that reduce nursing home admissions for people living with AD/ADRD. METHODS: We used a person‐level microsimulation to model the hazard ratios (HR) on nursing home admission for four evidence‐based interventions compared to usual care: Maximizing Independence at Home (MIND), NYU Caregiver (NYU); Alzheimer's and Dementia Care (ADC); and Adult Day Service Plus (ADS Plus). We evaluated societal costs, quality‐adjusted life years and incremental cost‐effectiveness ratios. RESULTS: All four interventions cost less and are more effective (i.e., cost savings) than usual care from a societal perspective. Results did not materially change in 1‐way, 2‐way, structural, and probabilistic sensitivity analyses. CONCLUSION: Dementia‐care interventions that reduce nursing home admissions save societal costs compared to usual care. Policies should incentivize providers and health systems to implement non‐pharmacologic interventions.
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Individual studies of care coordination have shown reduced care home admission and cost-effectiveness from a societal and individual perspective, but a meta-analysis of 14 care coordination RCTs did not show a statistically significant reduction in care home admission or hospitalisation.
“Individual studies of care coordination have shown reduced care home admission, and cost-effectiveness from a societal and individual perspective,(479) but a meta-analysis of 14 care coordination RCTs did not show a statistically significant reduction in care home admission or hospitalisation. (478)”
From Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission (2024) · cites this paper as [479]
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The Disproportionate Impact Of Dementia On Family And Unpaid Caregiving To Older Adults
Kasper, J. D., Freedman, V. A., Spillman, B. C., & Wolff, J. L. (2015) · Health Affairs · doi:10.1377/hlthaff.2015.0536 · Cited by 354 · see citing works
Gitlin, L. N., Marx, K., Stanley, I. H., & Hodgson, N. (2015) · The Gerontologist · doi:10.1093/geront/gnu123 · Cited by 336 · see citing works
Self-citationHogan, D. B., Bailey, P., Black, S., Carswell, A., Chertkow, H., Clarke, B., Cohen, C., Fisk, J. D., Forbes, D., Man-Son-Hing, M., et al. (2008) · Canadian Medical Association Journal · doi:10.1503/cmaj.081103 · Cited by 167 · see citing works
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Research works printed but not linked: 48
- [1]2021 Alzheimer’s disease facts and figures. Alzheimers Dement. 2021; 17(3): 327– 406. 33756057
- [2]Hurd MD, Martorell P, Delavande A, Monetary costs of dementia in the United States. N Engl J Med. 2013; 368(14): 1326– 1334. 23550670 PMC3959992
- [3]Jutkowitz E, Kane RL, Gaugler JE, Societal and family lifetime cost of dementia: implications for policy. J Am Geriatr Soc. 2017; 65(10): 2169– 2175. 28815557 PMC5657516
- [4]Committee on Family Caregiving for Older Adults; Board on Health Care Services; Health and Medicine Division; National Academies of Sciences, Engineering, and Medicine. Families Caring for an Aging America. Schulz R, Eden J, eds. National Academies Press (US); 2016. 27905704
- [5]Wiles JL, Leibing A, Guberman N, The meaning of “aging in place” to older people. Gerontologist. 2012; 52(3): 357– 366. 21983126
- [6]Robison J, Porter M, Shugrue N, Connecticut’s “Money follows the person” yields positive results for transitioning people out of institutions. Health Aff (Millwood). 2015; 34(10): 1628– 1636. 26438737
- [9]Jutkowitz E, Gaugler JE, Trivedi AN, Family caregiving in the community up to 8-years after onset of dementia. BMC Geriatr. 2020; 20(1): 216. 32560701 PMC7304188
- [10]Livingston G, Sommerlad A, Orgeta V, Dementia prevention, intervention, and care. Lancet. 2017; 390(10113): 2673– 2734. 28735855
- [12]Wolff JL, Spillman BC, Freedman VA, A national profile of family and unpaid caregivers who assist older adults with health care activities. JAMA Intern Med. 2016; 176(3): 372– 379. 26882031 PMC4802361
- [13]Samus Q, Johnston D, Black B, A multidimensional home-based care coordination intervention for elders with memory disorders: the Maximizing Independence at Home (MIND) pilot randomized trial. Am J Geriatr Psychiatry. 2014; 22(4): 398– 414. 24502822 PMC4034346
- [14]Gitlin LN, Reever K, Dennis MP, Enhancing quality of life of families who use adult day services: short- and long-term effects of the adult day services plus program. Gerontologist. 2006; 46(5): 630– 639. 17050754
- [15]Gaugler JE, Roth DL, Haley WE, Can counseling and support reduce burden and depressive symptoms in caregivers of people with Alzheimer’s disease during the transition to institutionalization? Results from the New York University caregiver intervention study. J Am Geriatr Soc. 2008; 56(3): 421– 428. 18179495 PMC2700042
- [16]Jennings LA, Laffan AM, Schlissel AC, Health care utilization and cost outcomes of a comprehensive dementia care program for medicare beneficiaries. JAMA Intern Med. 2019; 179(2): 161– 166. 30575846 PMC6439653
- [17]Van’t Leven N, Prick AEJC, Groenewoud JG, Dyadic interventions for community-dwelling people with dementia and their family caregivers: a systematic review. Int Psychogeriatr. 2013; 25(10): 1581– 1603. 23883489
- [18]Hansen RA, Gartlehner G, Webb AP, Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer’s disease: a systematic review and meta-analysis. Clin Interv Aging. 2008; 3(2): 211– 225. 18686744 PMC2546466
- [19]Maust DT, Kim HM, Seyfried LS, Antipsychotics, other psychotropics, and the risk of death in patients with dementia: number needed to harm. JAMA Psychiatry. 2015; 72(5): 438– 445. 25786075 PMC4439579
- [22]Moore A, Patterson C, Lee L, Fourth Canadian Consensus Conference on the diagnosis and treatment of dementia: recommendations for family physicians. Can Fam Physician. 2014; 60(5): 433– 438. 24829003 PMC4020644
- [23]Gitlin LN, Kales HC, Lyketsos CG. Nonpharmacologic management of behavioral symptoms in dementia. JAMA. 2012; 308(19): 2020– 2029. 23168825 PMC3711645
- [24]Lyketsos CG, Colenda CC, Beck C, Position statement of the American Association for geriatric psychiatry regarding principles of care for patients with dementia resulting from Alzheimer disease. Am J Geriatr Psychiatry. 2006; 14(7): 561– 572. 16816009
- [26]Callahan CM, Sachs GA, Lamantia MA, Unroe KT, Arling G, Boustani MA. Redesigning systems of care for older adults with Alzheimer’s disease. Health Aff (Millwood). 2014; 33(4): 626– 632. 24711324 PMC5337406
- [27]Lees Haggerty K, Epstein-Lubow G, Spragens LH, Recommendations to improve payment policies for comprehensive dementia care. J Am Geriatr Soc. 2020; 68(11): 2478– 2485. 32975812
- [28]Boustani M, Alder CA, Solid CA, Reuben D. An alternative payment model to support widespread use of collaborative dementia care models. Health Aff Millwood. 2019; 38(1): 54– 59. 30615525
- [29]Hodgson N, Gitlin LN. Implementing and sustaining family care programs in real-world settings: Barriers and facilitators. In: Gaugler J, ed. Bridging the Family Care Gap. Elsevier; 2021: 179– 219.
- [31]Chrysanthopoulou SA, Rutter CM, Gatsonis CA. Bayesian versus Empirical Calibration of Microsimulation Models: a comparative analysis. Med Decis Making. 2021; 41(6): 714– 726. 33966518 PMC9294658
- [32]Shewmaker P, Chrysanthopoulou SA, Iskandar R, Microsimulation Model Calibration with Approximate Bayesian Computation in R: a tutorial. Med Decis Making. 2022; 42(5): 557– 570. 35311401 PMC9198004
- [33]Tanner JA, Black BS, Johnston D, A randomized controlled trial of a community-based dementia care coordination intervention: effects of MIND at Home on caregiver outcomes. Am J Geriatr Psychiatry. 2015; 23(4): 391– 402. 25260557 PMC4355038
- [34]Mittelman MS, Haley WE, Clay OJ, Roth DL. Improving caregiver well-being delays nursing home placement of patients with Alzheimer disease. Neurology. 2006; 67(9): 1592– 1599. 17101889
- [35]Gaugler JE, Reese M, Mittelman MS. Effects of the NYU caregiver intervention-adult child on residential care placement. Gerontologist. 2013; 53: 985– 997. 23339050 PMC3826164
- [36]Foldes SS, Moriarty JP, Farseth PH, Mittelman MS, Long KH. Medicaid savings from The New York University Caregiver Intervention for families with dementia. The Gerontologist. 2018; 58(2): e97– e106. 29106531
- [37]Neumann PJ, Hermann RC, Kuntz KM, Cost-effectiveness of donepezil in the treatment of mild or moderate Alzheimer’s disease. Neurology. 1999; 52(6): 1138– 1145. 10214734
- [38]MetLife Mature Market Institute. Market Survey of Long-Term Care Costs: The 2012 MetLife Market Survey of Nursing Home, Assisted Living, Adult Day Services, and Home Care Costs. MetLife Mature Market Institute; 2012: 1– 51. https://www.carolinafep.com/library/mmi2012-market-survey-long-term-care-costs.pdf
- [39]Chari AV, Engberg J, Ray KN, Mehrotra A. The opportunity costs of informal elder-care in the United States: new estimates from the American Time Use Survey. Health Serv Res. 2015; 50(3): 871– 882. 25294306 PMC4450934
- [40]Sculpher MJ, Basu A, Kuntz KM, Meltzer DO. Reflecting uncertainty in cost-effectiveness analysis. In: Neumann PJ, Ganiats TG, Russell LB, Sanders GD, Siegel JE, eds. Cost-Effectiveness in Health and Medicine. Oxford University Press; 2016.
- [41]Neumann PJ, Sanders GD, Russell LB, Siegel JE, Ganiats TG. Cost-Effectiveness in Health and Medicine. Oxford University Press; 2016.
- [42]Turner RM, Spiegelhalter DJ, Smith GCS, Thompson SG. Bias modelling in evidence synthesis. J R Stat Soc Ser A Stat Soc. 2009; 172(1): 21– 47. PMC2667303 19381328
- [43]Jalal H, Pechlivanoglou P, Krijkamp E, Alarid-Escudero F, Enns E, Hunink MGM. An overview of R in health decision sciences. Med Decis Making. 2017; 37(7): 735– 746. 28061043 PMC12185038
- [44]Krijkamp EM, Alarid-Escudero F, Enns EA, Jalal HJ, Hunink MGM, Pechlivanoglou P. Microsimulation modeling for health decision sciences using R: a tutorial. Med Decis Making. 2018; 38(3): 400– 422. 29587047 PMC6349385
- [46]Chen C, Zissimopoulos JM. Racial and ethnic differences in trends in dementia prevalence and risk factors in the United States. Alzheimers Dement Transl Res Clin Interv. 2018; 4: 510– 520. PMC6197734 30364652
- [47]Gitlin L, Maslow K, National Research Summit on Care, Services and Supports for Persons with Dementia and Their Caregivers. 2018. Accessed November 4, 2021. https://aspe.hhs.gov/sites/default/files/migrated_legacy_files//181216/FinalReport.pdf 31784409
- [48]Gitlin LN, Baier RR, Jutkowitz E, Dissemination and implementation of evidence-based dementia care using embedded pragmatic trials. J Am Geriatr Soc. 2020; 68(S2): S28– S36. 32589277 PMC7470172
- [49]Ito K, Chapman R, Pearson SD, Tafazzoli A, Yaffe K, Gurwitz JH. Evaluation of the cost-effectiveness of drug treatment for Alzheimer disease in a simulation model that includes caregiver and societal factors. JAMA Netw Open. 2021; 4(10): e2129392. 34677596 PMC8536950
- [50]Jutkowitz E, MacLehose RF, Gaugler JE, Dowd B, Kuntz KM, Kane RL. Risk factors associated with cognitive, functional, and behavioral trajectories of newly diagnosed dementia patients. J Gerontol A Biol Sci Med Sci. 2017; 72(2): 251– 258. 27129917 PMC5344797
- [51]Jutkowitz E, Kuntz KM, Dowd B, Gaugler JE, MacLehose RF, Kane RL. Effects of cognition, function, and behavioral and psychological symptoms on out-of-pocket medical and nursing home expenditures and time spent caregiving for persons with dementia. Alzheimers Dement. 2017; 13(7): 801– 809. 28161279 PMC5644025
- [52]Jutkowitz E, Kane RL, Dowd B, Gaugler JE, MacLehose RF, Kuntz KM, Effects of Cognition, Function, and Behavioral and Psychological Symptoms on Medicare Expenditures and Health Care Utilization for Persons With Dementia. J Gerontol: Ser A, 2017; 72(6), 818– 824. PMC6075208 28369209
- [53]Solomon TM, deBrosGB,Budson AE,Mirkovic N,MurphyCA,Solomon PR. Correlational analysis of 5 commonly used measures of cognitive functioning and mental status: an update. Am J Alzheimers Dis Other Demen. 2014; 29(8): 718– 722. 24829061 PMC10852956
- [54]Intrator O, Hiris J, Berg K, Miller SC, Mor V. The residential history file: studying nursing home residents’ long-term care histories (*). Health Serv Res. 2011 Feb; 46(1 Pt 1): 120– 37. doi: 10.1111/j.1475-6773.2010.01194.x 21029090 PMC3015013 · DOI
- [56]Bharmal MF, Dedhiya S, Craig BA, Incremental dementiarelatedexpenditures in a Medicaid population. Am J Geriatr Psychiatry 2012; 20: 73– 83. 22183012
- [57]Mayeda ER, Glymour MM, Quesenberry CP, Johnson JK, Pérez-Stable EJ, Whitmer RA. Survival after dementia diagnosis in five racial/ethnic groups. Alzheimers Dement. 2017 Jul; 13(7): 761– 769. doi: 10.1016/j.jalz.2016.12.008 28174069 PMC5496783 · DOI
Cited by
Sorted by citations
Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission
Livingston, G., Huntley, J., Liu, K. Y., Costafreda, S. G., Selbæk, G., Alladi, S., Ames, D., Banerjee, S., Burns, A., Brayne, C., et al. (2024) · The Lancet · doi:10.1016/s0140-6736(24)01296-0 · Cited by 3,860 · see citing works
Self-citation
- Authors
- Jutkowitz, E., Pizzi, L. T., Shewmaker, P., Alarid‐Escudero, F., Epstein‐Lubow, G., Prioli, K. M., Gaugler, J. E., & Gitlin, L. N.
- Affiliations
- Brown University (US)
- Rutgers, The State University of New Jersey (US)
- Stanford University (US)
- Department of Health Services, Policy & Practice Brown University School of Public Health Providence Rhode Island USA
- University of Minnesota (US)
- Drexel University (US)
- Corresponding author
- Jutkowitz, Eric
- ORCID
- Venue
- Alzheimer's & Dementia
- Publisher
- Wiley
- Published
- 2023-04-06
- Volume
- 19
- Issue
- 9
- Pages
- 3867-3893
- ISSN
- 1552-5260 (ISSN-L)
- 1552-5279
- PMC
- PMC10524701
- OpenAlex
- W4362657255
- Cited by
- 22
- References
- 3
- Citations by year
- 2026: 6 · 2025: 11 · 2024: 3 · 2023: 2
- FWCI
- 4.48
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Alzheimer s & Dementia (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (1R21AG059623‐01, 1R01AG060871‐01, 1RF1AG069771, R01 AG049692)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Health Professions › General Health Professions › Geriatric Care and Nursing Homes
- Keywords
- dementia, Alzheimer's disease and related dementias
- MeSH terms
- Cost-Effectiveness Analysis, Adult, Alzheimer Disease, Cost-Benefit Analysis, Humans, Nursing Homes, Caregivers
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