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Cited by 244

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Spatial clustering of hemorrhages in probable cerebral amyloid angiopathy

Rosand, Jonathan, Muzikansky, Alona, Kumar, Ashok, Wisco, Jonathan J., Smith, Eric E., Betensky, Rebecca A., Greenberg, Steven M.·2005·Annals of Neurology

Abstract

Cerebral amyloid angiopathy (CAA) is a common cause of symptomatic intracerebral hemorrhage (ICH), as well as small asymptomatic hemorrhage in the elderly. We used gradient-echo MRI to analyze spatial distribution of 321 hemorrhages in 59 patients with probable CAA-related ICH. Hemorrhagic lesions were found preferentially in the temporal (ratio of actual to expected hemorrhages = 1.37) and occipital lobes (ratio = 1.45, p < 0.0001). Within individuals, hemorrhages tended to cluster, regardless of lobe (p < 0.0001). Among subjects followed prospectively for recurrence, clustering of new symptomatic and asymptomatic hemorrhages was observed. These data suggest that regional differences within the brain play a role in the development of CAA-related hemorrhage.

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Metadata

Authors
Rosand, J., Muzikansky, A., Kumar, A., Wisco, J. J., Smith, E. E., Betensky, R. A., & Greenberg, S. M.
Venue
Annals of Neurology
Publisher
Wiley
Published
2005
Volume
58
Issue
3
Pages
459-462
ISSN
  • 0364-5134 (ISSN-L)
  • 1531-8249
OpenAlex
W2124305917
Cited by
244
References
2
FWCI
5.85
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Spatial clustering of hemorrhages in probable cerebral amyloid angiopathy. https://app.cochat.ai/papers/10.1002/ana.20596
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Rosand, J., Muzikansky, A., Kumar, A., Wisco, J. J., Smith, E. E., Betensky, R. A., & Greenberg, S. M. (2005). Spatial clustering of hemorrhages in probable cerebral amyloid angiopathy. Annals of Neurology. https://doi.org/10.1002/ana.20596

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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