The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The pathophysiology of brain ischemia
Abstract
Brain ischemia due to a critical reduction in cerebral blood flow is a well recognized and common cause of irreversible brain damage. The observation that brain cells are more resistant to ischemia than was previously assumed on the basis of clinical experience has stimulated considerable investigative work designed to determine those factors responsible for irreversible ischemic cell damage. At this time, data from these investigations indicate that cellular acidosis and biochemical disturbances initiated by abnormal intracellular ion homeostasis may be especially important in determining the ultimate survival of nerve cells. This review examines the biochemical events initiated by ischemia and their potential role in determining the ultimate survival of brain cells.
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Citations
Cites
Thresholds in cerebral ischemia - the ischemic penumbra.
Astrup, J., Siesjö, B. K., & Symon, L. (1981) · Stroke · doi:10.1161/01.str.12.6.723 · Cited by 2,820
Cited by
Litvan, I., Agid, Y., Calne, D., Campbell, G., Dubois, B., Duvoisin, R. C., Goetz, C. G., Golbe, L. I., Grafman, J., Growdon, J. H., et al. (1996) · Neurology · doi:10.1212/wnl.47.1.1 · Cited by 2,538
Siesjö, B. K., & Bengtsson, F. (1989) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1989.20 · Cited by 1,231
Geula, C. (1998) · Neurology · doi:10.1212/wnl.51.1_suppl_1.s18 · Cited by 184
Lesions in the left arcuate fasciculus region and depressive symptoms in multiple sclerosis
Pujol, J., Bello, J., Deus, J., Martí-Vilalta, J. L., & Capdevila, A. (1997) · Neurology · doi:10.1212/wnl.49.4.1105 · Cited by 159
Hypoxia modulates nitric oxide-induced regulation of NMDA receptor currents and neuronal cell death
Gbadegesin, M., Vicini, S., Hewett, S. J., Wink, D. A., Espey, M., Pluta, R. M., & Colton, C. A. (1999) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1999.277.4.c673 · Cited by 47
Metadata
- Authors
- Raichle, M. E.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 1983-01
- Volume
- 13
- Issue
- 1
- Pages
- 2-10
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W1985939052
- Cited by
- 634
- References
- 1
- FWCI
- 28.33
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.