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Cited by 377

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Hyponatremia and cerebral infarction in patients with ruptured intracranial aneurysms: Is fluid restriction harmful?

Wijdicks, E. F. M., Vermeulen, M., Hijdra, A., van Gijn, J.·1985·Annals of Neurology

Abstract

We studied retrospectively the relationship between hyponatremia and cerebral infarction in 134 consecutive patients with aneurysmal subarachnoid hemorrhage. In 44 patients sodium levels fell below 135 mmol/L on at least two consecutive days between the second and the tenth day after the hemorrhage. Twenty‐five of these patients fulfilled the criteria for the syndrome of inappropriate secretion of antidiuretic hormane. Cerebral infarction developed in 27 of the 44 patients with hyponatremia and in 19 of the 90 patients with normal serum sodium levels (p < 0.001). Cerebral infarctions were more often fatal in patients with hyponatremia (p < 0.01). Twenty‐six of the 44 patients had been treated with fluid restriction to correct the serum sodium levels, and infarctions developed in 21. Fluid restriction to correct hyponatremia appears to be potentially dangerous in patients with aneurysmal subarachnoid hemorrhage.

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Metadata

Authors
Wijdicks, E. F. M., Vermeulen, M., Hijdra, A., & van Gijn, J.
Venue
Annals of Neurology
Publisher
Wiley
Published
1985-02
Volume
17
Issue
2
Pages
137-140
ISSN
  • 0364-5134 (ISSN-L)
  • 1531-8249
OpenAlex
W2138337482
Cited by
377
References
1
FWCI
6.01
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Hyponatremia and cerebral infarction in patients with ruptured intracranial aneurysms: Is fluid restriction harmful? https://app.cochat.ai/papers/10.1002/ana.410170206
The paper
Wijdicks, E. F. M., Vermeulen, M., Hijdra, A., & van Gijn, J. (1985). Hyponatremia and cerebral infarction in patients with ruptured intracranial aneurysms: Is fluid restriction harmful? Annals of Neurology. https://doi.org/10.1002/ana.410170206

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