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Atypical presentation of progressive supranuclear palsy
Abstract
Four pathologically documented cases of profressice supranuclear palsy are reported. Two patients exhinited severe dementia and 2 parkinsonism; none had the classic opthalmoplegia. On retrospective analysis, clues to the diagnosis included early prominent gait disturbance, apraxia of eyelid opening in 1 patient, lack of tremor, poor response to levodopa‐carbidopa, and severe rigidity with a posture of neck extension terminally in 1 patient. The clinical presentation of progressive supranuclear palsy, therefore, is not as stereotyped as previously thought, and the diagnosis can be overlooked if one adheres rigidly to the classic diagnostic criteria.
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Cited by
Litvan, I., Agid, Y., Calne, D., Campbell, G., Dubois, B., Duvoisin, R. C., Goetz, C. G., Golbe, L. I., Grafman, J., Growdon, J. H., et al. (1996) · Neurology · doi:10.1212/wnl.47.1.1 · Cited by 2,538
Respondek, G., Stamelou, M., Kurz, C., Ferguson, L. W., Rajput, A., Chiu, W. Z., van Swieten, J. C., Troakes, C., al Sarraj, S., Gelpi, E., et al. (2014) · Movement Disorders · doi:10.1002/mds.26054 · Cited by 384
Lackner, J. R., & DiZio, P. (1992) · The Head-Neck Sensory Motor System · doi:10.1093/acprof:oso/9780195068207.003.0033 · Cited by 11
Metadata
- Authors
- Davis, P. H., Bergeron, C., & McLachlan, D. R.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 1985-04
- Volume
- 17
- Issue
- 4
- Pages
- 337-343
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2059678380
- Cited by
- 239
- References
- 0
- FWCI
- 4.83
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Atypical presentation of progressive supranuclear palsy. https://app.cochat.ai/papers/10.1002/ana.410170406
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- Davis, P. H., Bergeron, C., & McLachlan, D. R. (1985). Atypical presentation of progressive supranuclear palsy. Annals of Neurology. https://doi.org/10.1002/ana.410170406
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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