The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Genetic evidence for the involvement of τ in progressive supranuclear palsy
Abstract
A dinucleotide repeat polymorphism in a τ intron was identified and used in a case‐control study to analyze the genetic association of τ with several neurodegenerative disease with τ pathology. Subjects with the homozygous τ AO alleles were excessively represented in the progressive supranuclear palsy (PSP) group, compared with the age‐matched healthy control group. Consequently, this allele is more frequently found in PSP than in a group of healthy subjects. This trend was not found in Alzheimer's disease or parkinsonism‐dementia complex of Guam, both of which are accompanied by major τ pathology. The result suggests τ possible involvement of τ in the pathogenesis of PSP.
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Cites
Identification of the Cystic Fibrosis Gene: Genetic Analysis
Kerem, B.-S., Rommens, J. M., Buchanan, J. A., Markiewicz, D., Cox, T. K., Chakravarti, A., Buchwald, M., & Tsui, L.-C. (1989) · Science · doi:10.1126/science.2570460 · Cited by 4,142
Cited by
Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
Hutton, M., Lendon, C. L., Rizzu, P., Baker, M., Froelich, S., Houlden, H., Pickering-Brown, S., Chakraverty, S., Isaacs, A., Grover, A., et al. (1998) · Nature · doi:10.1038/31508 · Cited by 3,498
Self-citationLee, V. M.-Y., Goedert, M., & Trojanowski, J. Q. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.1121 · Cited by 2,480
Self-citationMutation in the tau gene in familial multiple system tauopathy with presenile dementia
Spillantini, M. G., Murrell, J. R., Goedert, M., Farlow, M. R., Klug, A., & Ghetti, B. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.13.7737 · Cited by 1,474
Tau is a candidate gene for chromosome 17 frontotemporal dementia
Poorkaj, P., Bird, T. D., Wijsman, E., Nemens, E., Garruto, R. M., Anderson, L., Andreadis, A., Wiederholt, W. C., Raskind, M., & Schellenberg, G. D. (1998) · Annals of Neurology · doi:10.1002/ana.410430617 · Cited by 1,374
Self-citationTau pathology and neurodegeneration
Spillantini, M. G., & Goedert, M. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70090-5 · Cited by 1,133
Metadata
- Authors
- Conrad, C., Andreadis, A., Trojanowski, J. Q., Dickson, D. W., Kang, D., Chen, X., Wiederholt, W., Hansen, L., Masliah, E., Thal, L. J., Katzman, R., Xia, Y., & Saitoh, T.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 1997-02
- Volume
- 41
- Issue
- 2
- Pages
- 277-281
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2111567107
- Cited by
- 388
- References
- 1
- FWCI
- 16.27
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Genetic evidence for the involvement of τ in progressive supranuclear palsy. https://app.cochat.ai/papers/10.1002/ana.410410222
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- Conrad, C., Andreadis, A., Trojanowski, J. Q., Dickson, D. W., Kang, D., Chen, X., Wiederholt, W., Hansen, L., Masliah, E., Thal, L. J., Katzman, R., Xia, Y., & Saitoh, T. (1997). Genetic evidence for the involvement of τ in progressive supranuclear palsy. Annals of Neurology. https://doi.org/10.1002/ana.410410222
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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