Tau pathology and neurodegeneration

Neuropathological stageing of Alzheimer-related changes.

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Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

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Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

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Triple-Transgenic Model of Alzheimer’s Disease with Plaques and Tangles

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Clinical and biomarker changes in dominantly inherited Alzheimer's disease

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Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

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Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

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Stages in the development of Parkinson’s disease-related pathology

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

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Chronic traumatic encephalopathy in athletes: Progressive tauopathy after repetitive head injury

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Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model

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A Century of Alzheimer's Disease

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The spectrum of disease in chronic traumatic encephalopathy

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Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

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Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model

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Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

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Transmission and spreading of tauopathy in transgenic mouse brain

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Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

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Alzheimer Mechanisms and Therapeutic Strategies

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A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

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Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP

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The distribution of tau in the mammalian central nervous system.

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Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

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Editorial on Consensus Recommendations for the Postmortem Diagnosis of Alzheimer Disease from the National Institute on Aging and the Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer Disease

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Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

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Uber eine eigenartige Erkrankung der Hirnrinde

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Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

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Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

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A68: a Major Subunit of Paired Helical Filaments and Derivatized Forms of Normal Tau

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Tau is a candidate gene for chromosome 17 frontotemporal dementia

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Propagation of Tau Misfolding from the Outside to the Inside of a Cell

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100 years of Lewy pathology

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Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein

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Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

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Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

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Tau proteins of alzheimer paired helical filaments: Abnormal phosphorylation of all six brain isoforms

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Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

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Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

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Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif ( ³⁰⁶ VQIVYK ³¹¹ ) forming β structure

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Trans-Synaptic Spread of Tau Pathology In Vivo

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Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease

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Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

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Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

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Enhancement of proteasome activity by a small-molecule inhibitor of USP14

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Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease.

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Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization.

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Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

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Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease

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Ubiquitin Is a Component of Paired Helical Filaments in Alzheimer's Disease

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Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease

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A common inversion under selection in Europeans

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The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease.

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The pathological process underlying Alzheimer’s disease in individuals under thirty

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Tau is essential to β-amyloid-induced neurotoxicity

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Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum

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Association of an Extended Haplotype in the Tau Gene with Progressive Supranuclear Palsy

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O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease

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Punch drunk

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Altered microtubule organization in small-calibre axons of mice lacking tau protein

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Abundant Tau Filaments and Nonapoptotic Neurodegeneration in Transgenic Mice Expressing Human P301S Tau Protein

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CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

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The acetylation of tau inhibits its function and promotes pathological tau aggregation

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The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

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Advanced Maillard reaction end products are associated with Alzheimer disease pathology.

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Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer’s disease

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über eigenartige Krankheitsfälle des späteren Alters

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Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration <i>in vivo</i>

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Early Clinical PET Imaging Results with the Novel PHF-Tau Radioligand [F18]-T808

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Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference

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Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy

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Discovery of previously unidentified genomic disorders from the duplication architecture of the human genome

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Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

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Amyloid-β/Fyn–Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease

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Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807

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Regulation of Tau Pathology by the Microglial Fractalkine Receptor

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Seeding of Normal Tau by Pathological Tau Conformers Drives Pathogenesis of Alzheimer-like Tangles

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Structure and novel exons of the human .tau. gene

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The Prevalence and Malignancy of Alzheimer Disease

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Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation

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Aging: What We Can Learn From Elephants

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Arsenic and Tau Phosphorylation: A Mechanistic Review

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