The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Farnesyl‐pyrophosphat und 3‐Methyl‐Δ3‐butenyl‐1‐pyrophosphat, die biologischen Vorstufen des Squalens. Zur Biosynthese der Terpene, III
Abstract
Zellfreie Hefeextrakte führen markierte Mevalonsäure in Squalen über. Es wird über Versuche berichtet, in denen zwei neue Zwischenprodukte isoliert und als Isopentenyl‐pyrophosphat und Farnesyl‐pyrophosphat identifiziert werden konnten. Die präparative Synthese von Isopentenyl‐pyrophosphat wird beschrieben und seine biologische Umwandlung in Farnesyl‐pyrophosphat und Squalen diskutiert. Die markierte Verbindung ließ sich mit Enzymen anderer Herkunft in Cholesterin und Kautschuk inkorporieren und erwies sich damit als der universelle Baustein der unter die „Isopren‐Regel”︁ fallenden Naturstoffe.
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Citations
Cites
The isoprene rule and the biogenesis of terpenic compounds
Ruzicka, L. (1953) · Experientia · doi:10.1007/bf02167631 · Cited by 739
Cantoni, G. L. (1953) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)66148-4 · Cited by 571
ACTIVATION OF METHIONINE FOR TRANSMETHYLATION
Cantoni, G. L., & Durell, J. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64899-9 · Cited by 164
Cornforth, J. W., Cornforth, R. H., Popják, G. J., et al. (1958) · Biochemical Journal · doi:10.1042/bj0690146 · Cited by 132
Oxidative phosphorylation by subcellular particles from yeast
Utter, M. F., KEECH, D. B., & Nossal, P. M. (1958) · Biochemical Journal · doi:10.1042/bj0680431 · Cited by 55
Cited by
The Biological Synthesis of Cholesterol
Bloch, K. (1965) · Science · doi:10.1126/science.150.3692.19 · Cited by 560
A raison d’être for two distinct pathways in the early steps of plant isoprenoid biosynthesis?
Hemmerlin, A., Harwood, J. L., & Bach, T. J. (2012) · Progress in Lipid Research · doi:10.1016/j.plipres.2011.12.001 · Cited by 356
Biochemistry of Mitochondrial Coenzyme Q Biosynthesis
Stefely, J. A., & Pagliarini, D. J. (2017) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2017.06.008 · Cited by 331
De novo synthesis of monoterpenes by Saccharomyces cerevisiae wine yeasts
Carrau, F. M., Medina, K., Boido, E., Farina, L., Gaggero, C., Dellacassa, E., Versini, G., & Henschke, P. A. (2005) · FEMS Microbiology Letters · doi:10.1016/j.femsle.2004.11.050 · Cited by 245
Metadata
- Authors
- Lynen, F., Eggerer, H., Henning, U., & Kessel, I.
- Venue
- Angewandte Chemie
- Publisher
- Wiley
- Published
- 1958-12-21
- Volume
- 70
- Issue
- 24
- Pages
- 738-742
- ISSN
- 0044-8249 (ISSN-L)
- 1521-3757
- OpenAlex
- W2157531346
- Cited by
- 265
- References
- 5
- FWCI
- 13.39
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Farnesyl‐pyrophosphat und 3‐Methyl‐Δ3‐butenyl‐1‐pyrophosphat, die biologischen Vorstufen des Squalens. Zur Biosynthese der Terpene, III. https://app.cochat.ai/papers/10.1002/ange.19580702403
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- Lynen, F., Eggerer, H., Henning, U., & Kessel, I. (1958). Farnesyl‐pyrophosphat und 3‐Methyl‐Δ3‐butenyl‐1‐pyrophosphat, die biologischen Vorstufen des Squalens. Zur Biosynthese der Terpene, III. Angewandte Chemie. https://doi.org/10.1002/ange.19580702403
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