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Titelbild: Umkodierung des genetischen Codes mit Selenocystein (Angew. Chem. 1/2014)
Open accessAbstract
Das nach Selene, der Mondgöttin benannte Selenocystein (Sec) zeichnet sich durch eine einzigartige Katalysekraft und die Insertion in Proteine durch die Umkodierung spezifischer UGA-Stopcodons zu Sec aus. In der Zuschrift auf S. 325 ff. beschreiben D. Söll, P. O'Donoghue et al. die Entwicklung einer Sec-Insertions-Maschinerie, um fast alle 64 Codons umzukodieren. Dabei ist die ringförmige decamere Selenocystein-Synthase SeIA für die Bereitstellung von tRNA-gebundenem Sec als zentralem Baustein für die Selenoproteintranslation essenziell.
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Cited by
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Cai, Y., Zhang, G., & Zhang, Y.-W. (2015) · The Journal of Physical Chemistry C · doi:10.1021/acs.jpcc.5b02634 · Cited by 354
Zhou, X., Jiang, J., Ding, T., Zhang, J., Pan, B., Zuo, J., & Yang, Q. (2014) · Nanoscale · doi:10.1039/c4nr02716g · Cited by 206
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Gao, S., Li, G.-D., Liu, Y., Chen, H., Feng, L.-L., Wang, Y., Yang, M., Wang, D., Wang, S., & Zou, X. (2015) · Nanoscale · doi:10.1039/c4nr04924a · Cited by 180
Medeiros, N. G., Braga, C. A., Câmara, V. S., Duarte, R. C., & Rodembusch, F. S. (2022) · Asian Journal of Organic Chemistry · doi:10.1002/ajoc.202200095 · Cited by 36
Metadata
- Authors
- Bröcker, M. J., Ho, J. M. L., Church, G. M., Söll, D., & O'Donoghue, P.
- Venue
- Angewandte Chemie
- Publisher
- Wiley
- Published
- 2013-12-23
- Volume
- 126
- Issue
- 1
- Pages
- 1-1
- ISSN
- 0044-8249 (ISSN-L)
- 1521-3757
- OpenAlex
- W2015326770
- Cited by
- 183
- References
- 0
- FWCI
- 12.24
- Type
- journal article
- Language
- de
- Open access
- bronze
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- Bröcker, M. J., Ho, J. M. L., Church, G. M., Söll, D., & O'Donoghue, P. (2014). Titelbild: Umkodierung des genetischen Codes mit Selenocystein (Angew. Chem. 1/2014). Angewandte Chemie. https://doi.org/10.1002/ange.201310509
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