The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Molecular Engineering of DNA: Molecular Beacons
Open accessAbstract
Molecular beacons (MBs) are specifically designed DNA hairpin structures that are widely used as fluorescent probes. Applications of MBs range from genetic screening, biosensor development, biochip construction, and the detection of single‐nucleotide polymorphisms to mRNA monitoring in living cells. The inherent signal‐transduction mechanism of MBs enables the analysis of target oligonucleotides without the separation of unbound probes. The MB stem–loop structure holds the fluorescence‐donor and fluorescence‐acceptor moieties in close proximity to one another, which results in resonant energy transfer. A spontaneous conformation change occurs upon hybridization to separate the two moieties and restore the fluorescence of the donor. Recent research has focused on the improvement of probe composition, intracellular gene quantitation, protein–DNA interaction studies, and protein recognition.
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Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid
WATSON, J. D., & CRICK, F. H. C. (1953) · Nature · doi:10.1038/171737a0 · Cited by 13,584
Mfold web server for nucleic acid folding and hybridization prediction
Zuker, M. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg595 · Cited by 13,404
The Structure of Haplotype Blocks in the Human Genome
Gabriel, S. B., Schaffner, S. F., Nguyen, H., Moore, J. M., Roy, J., Blumenstiel, B., Higgins, J., DeFelice, M., Lochner, A., Faggart, M., et al. (2002) · Science · doi:10.1126/science.1069424 · Cited by 5,863
Searching for genetic determinants in the new millennium
Risch, N. J. (2000) · Nature · doi:10.1038/35015718 · Cited by 1,839
LNA (Locked Nucleic Acid): High-Affinity Targeting of Complementary RNA and DNA
Vester, B., & Wengel, J. (2004) · Biochemistry · doi:10.1021/bi0485732 · Cited by 727
Cited by
Hildebrandt, N., Spillmann, C. M., Algar, W. R., Pons, T., Stewart, M. H., Oh, E., Susumu, K., Díaz, S. A., Delehanty, J. B., & Medintz, I. L. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00030 · Cited by 730
Electrochemistry of Nucleic Acids
Paleček, E., & Bartošík, M. (2012) · Chemical Reviews · doi:10.1021/cr200303p · Cited by 668
Wang, F., Lu, C.-H., & Willner, I. (2014) · Chemical Reviews · doi:10.1021/cr400354z · Cited by 649
Functional nanoprobes for ultrasensitive detection of biomolecules
Song, S., Qin, Y., He, Y., Huang, Q., Fan, C., & Chen, H.-Y. (2010) · Chemical Society Reviews · doi:10.1039/c000682n · Cited by 592
Nucleic Acid Based Molecular Devices
Krishnan, Y., & Simmel, F. C. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.200907223 · Cited by 572
Metadata
- Authors
- Wang, K., Tang, Z., Yang, C. J., Kim, Y., Fang, X., Li, W., Wu, Y., Medley, C. D., Cao, Z., Li, J., Colon, P., Lin, H., & Tan, W.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2009-01-13
- Volume
- 48
- Issue
- 5
- Pages
- 856-870
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2137458512
- Cited by
- 644
- References
- 6
- FWCI
- 18.12
- Type
- journal article
- Language
- en
- Open access
- green
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- Wang, K., Tang, Z., Yang, C. J., Kim, Y., Fang, X., Li, W., Wu, Y., Medley, C. D., Cao, Z., Li, J., Colon, P., Lin, H., & Tan, W. (2009). Molecular Engineering of DNA: Molecular Beacons. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200800370
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