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A Genetically Encoded Boronate‐Containing Amino Acid
Open accessAbstract
A biological boronate: An orthogonal tRNA/aminoacyl-tRNA synthetase pair has been evolved for the genetic incorporation of a boronic acid into proteins. This amino acid has been used to purify proteins in a one-step scarless purification procedure as well as for the site-specific labeling of proteins using various boronic acid chemistries.
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Citations
Cites
Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acids
Adams, J., Behnke, M., Chen, S., Cruickshank, A. A., Dick, L. R., Grenier, L., Klunder, J. M., Ma, Y.-T., Plamondon, L., & Stein, R. L. (1998) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(98)00029-8 · Cited by 685
Cited by
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
Sletten, E. M., & Bertozzi, C. R. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200900942 · Cited by 3,165
Adding New Chemistries to the Genetic Code
Liu, C. C., & Schultz, P. G. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.052308.105824 · Cited by 1,725
Self-citationExpanding and Reprogramming the Genetic Code of Cells and Animals
Chin, J. W. (2014) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060713-035737 · Cited by 476
Algar, W. R., Prasuhn, D. E., Stewart, M. H., Jennings, T. L., Blanco-Canosa, J. B., Dawson, P. E., & Medintz, I. L. (2011) · Bioconjugate Chemistry · doi:10.1021/bc200065z · Cited by 502
Boronic acids as building blocks for the construction of therapeutically useful bioconjugates
António, J. P. M., Russo, R., Carvalho, C. P., Cal, P. M. S. D., & Gois, P. M. P. (2019) · Chemical Society Reviews · doi:10.1039/c9cs00184k · Cited by 303
Metadata
- Authors
- Brustad, E., Bushey, M. L., Lee, J. W., Groff, D., Liu, W., & Schultz, P. G.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2008-10-09
- Volume
- 47
- Issue
- 43
- Pages
- 8220-8223
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W4230849949
- Cited by
- 174
- References
- 1
- FWCI
- 5.21
- Type
- journal article
- Language
- en
- Open access
- green
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- Brustad, E., Bushey, M. L., Lee, J. W., Groff, D., Liu, W., & Schultz, P. G. (2008). A Genetically Encoded Boronate‐Containing Amino Acid. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200803240
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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