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Bioorthogonal Turn‐On Probes for Imaging Small Molecules inside Living Cells
Open accessAbstract
Glowing tags: a series of activatable ("turn-on") tetrazine-conjugated fluorescent probes was developed, which react rapidly in an inverse-electron-demand [4+2] cycloaddition with strained dienophiles such as trans-cyclooctene, thereby strongly increasing the fluorescence intensity. The novel turn-on probes were applied for intracellular live-cell imaging of a microtubuli-binding trans-cyclooctene modified taxol.
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Citations
Cited by
BODIPY-based probes for the fluorescence imaging of biomolecules in living cells
Kowada, T., Maeda, H., & Kikuchi, K. (2015) · Chemical Society Reviews · doi:10.1039/c5cs00030k · Cited by 1,381
Tassa, C., Shaw, S. Y., & Weissleder, R. (2011) · Accounts of Chemical Research · doi:10.1021/ar200084x · Cited by 653
Self-citationBioorthogonal Reactions for Labeling Proteins
Lang, K., & Chin, J. W. (2014) · ACS Chemical Biology · doi:10.1021/cb4009292 · Cited by 555
Labeling and Single-Molecule Methods To Monitor G Protein-Coupled Receptor Dynamics
Tian, H., Fürstenberg, A., & Huber, T. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00084 · Cited by 114
Tallon, A. M., Xu, Y., West, G. M., am Ende, C. W., & Fox, J. M. (2023) · Journal of the American Chemical Society · doi:10.1021/jacs.3c04444 · Cited by 43
Metadata
- Authors
- Devaraj, N. K., Hilderbrand, S., Upadhyay, R., Mazitschek, R., & Weissleder, R.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2010-03-30
- Volume
- 49
- Issue
- 16
- Pages
- 2869-2872
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2155827990
- Cited by
- 457
- References
- 0
- FWCI
- 13.89
- Type
- journal article
- Language
- en
- Open access
- green
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- Devaraj, N. K., Hilderbrand, S., Upadhyay, R., Mazitschek, R., & Weissleder, R. (2010). Bioorthogonal Turn‐On Probes for Imaging Small Molecules inside Living Cells. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200906120
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
