The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
A Tumor‐Acidity‐Activated Charge‐Conversional Nanogel as an Intelligent Vehicle for Promoted Tumoral‐Cell Uptake and Drug Delivery
Abstract
A positive (or negative) chameleon: A nanogel that is negatively charged at physiological pH values and activated to be positively charged at tumor extracellular pH values was internalized efficiently by tumor cells both in vitro and in vivo (see illustration). Intracellular drug release was also enhanced, probably as a result of a decrease in the interaction between the drug and the nanogel in its protonated state.
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Cites
The effect of particle design on cellular internalization pathways
Gratton, S. E. A., Ropp, P. A., Pohlhaus, P. D., Luft, J. C., Madden, V. J., Napier, M. E., & DeSimone, J. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801763105 · Cited by 2,918
Multifunctional and stimuli-sensitive pharmaceutical nanocarriers
Torchilin, V. (2009) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2008.09.026 · Cited by 583
“SMART” Drug Delivery Systems: Double-Targeted pH-Responsive Pharmaceutical Nanocarriers
Sawant, R. M., Hurley, J. P., Salmaso, S., Kale, A., Tolcheva, E., Levchenko, T. S., & Torchilin, V. P. (2006) · Bioconjugate Chemistry · doi:10.1021/bc060080h · Cited by 540
Cited by
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
Sun, T., Zhang, Y. S., Pang, B., Hyun, D. C., Yang, M., & Xia, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201403036 · Cited by 2,164
Self-citationUlbrich, K., Holá, K., Šubr, V., Bakandritsos, A., Tuček, J., & Zbořil, R. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00589 · Cited by 1,730
Kocak, G., Tuncer, C., & Bütün, V. (2017) · Polymer Chemistry · doi:10.1039/c6py01872f · Cited by 1,189
Fleige, E., Quadir, M. A., & Haag, R. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.01.020 · Cited by 1,111
The Smart Drug Delivery System and Its Clinical Potential
Liu, D., Yang, F., Xiong, F., & Gu, N. (2016) · Theranostics · doi:10.7150/thno.14858 · Cited by 1,066
Metadata
- Authors
- Du, J., Sun, T., Song, W., Wu, J., & Wang, J.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2010-05-06
- Volume
- 49
- Issue
- 21
- Pages
- 3621-3626
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2121781418
- Cited by
- 520
- References
- 3
- FWCI
- 10.86
- Type
- journal article
- Language
- en
- Open access
- closed
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- Du, J., Sun, T., Song, W., Wu, J., & Wang, J. (2010). A Tumor‐Acidity‐Activated Charge‐Conversional Nanogel as an Intelligent Vehicle for Promoted Tumoral‐Cell Uptake and Drug Delivery. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200907210
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