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A Graphene‐Based Platform for the Assay of Duplex‐DNA Unwinding by Helicase
Open accessAbstract
Time to unwind: Graphene oxide (GO) enables the quantitative measurement of helicase-dependent double-stranded DNA (dsDNA) unwinding activity in real time. GO selectively binds to unwound fluorescent-dye-labeled single-stranded DNA and quenches its fluorescence (see picture). The helicase activity is monitored by following the change in fluorescence.
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Cites
Molecular mechanism of nucleotide excision repair
de Laat, W. L., Jaspers, N. G. J., & Hoeijmakers, J. H. J. (1999) · Genes & Development · doi:10.1101/gad.13.7.768 · Cited by 1,122
Cited by
New Horizons for Diagnostics and Therapeutic Applications of Graphene and Graphene Oxide
Feng, L., Wu, L., & Qu, X. (2013) · Advanced Materials · doi:10.1002/adma.201203229 · Cited by 632
Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic
Weiss, C., Carriere, M., Fusco, L., Capua, I., Regla-Nava, J. A., Pasquali, M., Scott, J. A., Vitale, F., Unal, M. A., Mattevi, C., et al. (2020) · ACS Nano · doi:10.1021/acsnano.0c03697 · Cited by 601
Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery
Panwar, N., Soehartono, A. M., Chan, K. K., Zeng, S., Xu, G., Qu, J., Coquet, P., Yong, K.-T., & Chen, X. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00099 · Cited by 555
Adsorption and Desorption of DNA on Graphene Oxide Studied by Fluorescently Labeled Oligonucleotides
Wu, M., Kempaiah, R., Huang, P.-J. J., Maheshwari, V., & Liu, J. (2011) · Langmuir · doi:10.1021/la1037926 · Cited by 527
Investigating Protein–Ligand Interactions by Solution Nuclear Magnetic Resonance Spectroscopy
Becker, W., Bhattiprolu, K. C., Gubensäk, N., & Zangger, K. (2018) · ChemPhysChem · doi:10.1002/cphc.201701253 · Cited by 138
Metadata
- Authors
- Jang, H., Kim, Y., Kwon, H., Yeo, W., Kim, D., & Min, D.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2010-07-28
- Volume
- 49
- Issue
- 33
- Pages
- 5703-5707
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2107569536
- Cited by
- 241
- References
- 1
- FWCI
- 11.81
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Jang, H., Kim, Y., Kwon, H., Yeo, W., Kim, D., & Min, D. (2010). A Graphene‐Based Platform for the Assay of Duplex‐DNA Unwinding by Helicase. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201001332
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