The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Synthesis of 5‐Substituted 1 H‐Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High‐Temperature Microreactor Approach
Abstract
Harnessing hydrazoic acid in a microreactor! Tetrazoles have been synthesized in a very efficient manner by using a high-temperature/high-pressure process intensification regime. Despite the toxic and explosive nature of hydrazoic acid, the synthesis was conducted safely in continuous flow format with residence times as short as 2.5 minutes at 260 °C (see picture).
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Citations
Cites
Microchemical systems for continuous-flow synthesis
Hartman, R. L., & Jensen, K. F. (2009) · Lab on a Chip · doi:10.1039/b906343a · Cited by 508
Cited by
Taming hazardous chemistry by continuous flow technology
Movsisyan, M., Delbeke, E. I. P., Berton, J. K. E. T., Battilocchio, C., Ley, S. V., & Stevens, C. V. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00902b · Cited by 692
Continuous flow reactors: a perspective
Wiles, C., & Watts, P. (2012) · Green Chem. · doi:10.1039/c1gc16022b · Cited by 626
Dallinger, D., Gutmann, B., & Kappe, C. O. (2020) · Accounts of Chemical Research · doi:10.1021/acs.accounts.0c00199 · Cited by 163
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Metadata
- Authors
- Gutmann, B., Roduit, J., Roberge, D., & Kappe, C. O.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2010-08-18
- Volume
- 49
- Issue
- 39
- Pages
- 7101-7105
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2157731110
- Cited by
- 183
- References
- 1
- FWCI
- 9.31
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gutmann, B., Roduit, J., Roberge, D., & Kappe, C. O. (2010). Synthesis of 5‐Substituted 1 H‐Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High‐Temperature Microreactor Approach. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201003733
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