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An Enzyme‐Responsive Polymeric Superamphiphile
Abstract
Responding to treatment: A superamphiphile is formed between a double-hydrophilic polymer (methoxy-poly(ethylene glycol)-block-poly(L-lysine hydrochloride)) and a natural enzyme-responsive molecule (adenosine 5′-triphosphate). The superamphiphile self-assembles into spherical aggregates, which, upon addition of enzymes, disassemble and release loaded molecules (see picture).
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Citations
Cited by
Block copolymer micelles in nanomedicine applications
Cabral, H., Miyata, K., Osada, K., & Kataoka, K. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00199 · Cited by 1,309
Ge, Z., & Liu, S. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60048c · Cited by 914
Enzyme-responsive polymeric assemblies, nanoparticles and hydrogels
Hu, J., Zhang, G., & Liu, S. (2012) · Chemical Society Reviews · doi:10.1039/c2cs35103j · Cited by 722
Selenium-Containing Polymers: Promising Biomaterials for Controlled Release and Enzyme Mimics
Xu, H., Cao, W., & Zhang, X. (2013) · Accounts of Chemical Research · doi:10.1021/ar4000339 · Cited by 586
Self-citationMultifunctional polymeric micelles for delivery of drugs and siRNA
Jhaveri, A. M., & Torchilin, V. P. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00077 · Cited by 466
Metadata
- Authors
- Wang, C., Chen, Q., Wang, Z., & Zhang, X.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2010-09-30
- Volume
- 49
- Issue
- 46
- Pages
- 8612-8615
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2159194625
- Cited by
- 207
- References
- 0
- FWCI
- 11.05
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: An Enzyme‐Responsive Polymeric Superamphiphile. https://app.cochat.ai/papers/10.1002/anie.201004253
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- Wang, C., Chen, Q., Wang, Z., & Zhang, X. (2010). An Enzyme‐Responsive Polymeric Superamphiphile. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201004253
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
