A New Dimension in Separation Science: Comprehensive Two‐Dimensional Gas Chromatography
Abstract
The introduction and development of comprehensive two‐dimensional gas chromatography offers greatly enhanced resolution and identification of organic analytes in complex mixtures compared to any one‐dimensional separation technique. Initially promoted by the need to resolve highly complex petroleum samples, the technique’s enormous separation power and enhanced ability to gather information has rapidly attracted the attention of analysts from all scientific fields. In this Minireview, we highlight the fundamental theory, recent advances, and future trends in the instrumentation and application of comprehensive two‐dimensional column separation.
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All five analysed amino acids exhibited e.e. values of identical sign for a given polarization and wavelength.
“Advantageously, all five amino acids exhibited e.e. values of identical sign for a given polarization and wavelength”
From Possible chemical and physical scenarios towards biological homochirality (2022) · cites this paper as [206]
CPL irradiation of interstellar ice analogues can form amino acids with e.e. up to 2.54 ± 0.28%.
“Sixteen amino acids were identified, and five of them (including alanine and valine) were analysed by enantioselective two-dimensional gas chromatography, GC Â GC, 206 coupled to TOF mass spectrometry, to show enantioenrichments of up to 2.54 Æ 0.28% e.e.”
From Possible chemical and physical scenarios towards biological homochirality (2022) · cites this paper as [206]
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Possible chemical and physical scenarios towards biological homochirality
Sallembien, Q., Bouteiller, L., Crassous, J., & Raynal, M. (2022) · Chemical Society Reviews · doi:10.1039/d1cs01179k · Cited by 186 · see citing works
The Astrophysical Formation of Asymmetric Molecules and the Emergence of a Chiral Bias
Garcia, A. D., Meinert, C., Sugahara, H., Jones, N. C., Hoffmann, S. V., & Meierhenrich, U. J. (2019) · Life · doi:10.3390/life9010029 · Cited by 47 · see citing works
Self-citation
- Authors
- Meinert, C., & Meierhenrich, U. J.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Meierhenrich, Uwe J.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2012-09-10
- Volume
- 51
- Issue
- 42
- Pages
- 10460-10470
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2110470789
- Cited by
- 106
- References
- 0
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 5 · 2023: 5 · 2022: 7 · 2021: 6 · 2020: 7 · 2019: 6 · 2018: 8 · 2017: 7 · 2016: 11 · 2015: 6 · 2014: 17 · 2013: 11 · 2012: 2
- FWCI
- 5.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Angewandte Chemie International Edition (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Agence Nationale de la Recherche (ANR-07-BLAN-0293)
- Topics
- Physical Sciences › Chemistry › Spectroscopy › Analytical Chemistry and Chromatography
- Physical Sciences › Chemistry › Analytical Chemistry › Spectroscopy and Chemometric Analyses
- Physical Sciences › Chemistry › Analytical Chemistry › Chromatography in Natural Products
- Keywords
- comprehensive two-dimensional gas chromatography, complex mixtures, petroleum analysis, separation resolution, chromatography instrumentation
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Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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