The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
On the Biological Properties of Alkynyl Phosphine Gold(I) Complexes
Abstract
Golden times for metal-based drugs? Alkynyl triphenylphosphine gold(I) complexes display interesting biological properties and show high potential for future drug development. They are strong inhibitors of the enzyme thioredoxin reductase, trigger antiproliferative effects in tumor cells, and influence tumor cell metabolism, mitochondrial respiration, and angiogenesis in zebrafish embryos.
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Cites
Thalidomide is an inhibitor of angiogenesis.
D'Amato, R. J., Loughnan, M. S., Flynn, E., & Folkman, J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.9.4082 · Cited by 2,454
Cited by
Bertrand, B., & Casini, A. (2014) · Dalton Trans. · doi:10.1039/c3dt52524d · Cited by 441
Next-Generation Metal Anticancer Complexes: Multitargeting via Redox Modulation
Romero-Canelón, I., & Sadler, P. J. (2013) · Inorganic Chemistry · doi:10.1021/ic400835n · Cited by 396
Metallodrugs in cancer nanomedicine
Peña, Q., Wang, A., Zaremba, O., Shi, Y., Scheeren, H. W., Metselaar, J. M., Kiessling, F., Pallares, R. M., Wuttke, S., & Lammers, T. (2022) · Chemical Society Reviews · doi:10.1039/d1cs00468a · Cited by 259
Zhong, H.-J., Lu, L., Leung, K.-H., Wong, C. C. L., Peng, C., Yan, S.-C., Ma, D.-L., Cai, Z., David Wang, H.-M., & Leung, C.-H. (2015) · Chemical Science · doi:10.1039/c5sc02321a · Cited by 138
Metadata
- Authors
- Meyer, A., Bagowski, C. P., Kokoschka, M., Stefanopoulou, M., Alborzinia, H., Can, S., Vlecken, D. H., Sheldrick, W. S., Wölfl, S., & Ott, I.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2012-07-29
- Volume
- 51
- Issue
- 35
- Pages
- 8895-8899
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2126737638
- Cited by
- 187
- References
- 1
- FWCI
- 6.96
- Type
- journal article
- Language
- en
- Open access
- closed
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- Meyer, A., Bagowski, C. P., Kokoschka, M., Stefanopoulou, M., Alborzinia, H., Can, S., Vlecken, D. H., Sheldrick, W. S., Wölfl, S., & Ott, I. (2012). On the Biological Properties of Alkynyl Phosphine Gold(I) Complexes. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201202939
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
