Metallodrugs in cancer nanomedicine
Abstract
Bridging inorganic medicinal chemistry and nanomedicine in cancer therapy: nanoformulations to improve the clinical translation of metallodrugs.
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Radiolabelling techniques utilizing bioorthogonal chemistry, click chemistry, and prosthetic groups for site-specific attachment enhance precision and stability of radiopharmaceuticals.
“Additionally, the introduction of radiolabelling techniques utilizing bioorthogonal chemistry, click chemistry, and prosthetic groups for site-specific attachment further enhances the precision and stability of radiopharmaceuticals [66].”
From Radiopharmaceuticals: navigating the frontier of precision medicine and therapeutic innovation (2024) · cites this paper as [66]
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Radiopharmaceuticals: navigating the frontier of precision medicine and therapeutic innovation
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“Additionally, the introduction of radiolabelling techniques utilizing bioorthogonal chemistry, click chemistry, and prosthetic groups for site-specific attachment further enhances the precision and stability of radiopharma-ceuticals [66].”
BackgroundGlutathione-responsive and -exhausting metal nanomedicines for robust synergistic cancer therapy
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- Authors
- Peña, Q., Wang, A., Zaremba, O., Shi, Y., Scheeren, H. W., Metselaar, J. M., Kiessling, F., Pallares, R. M., Wuttke, S., & Lammers, T.
- Affiliations
- Universitätsklinikum Aachen (DE)
- Basque Center for Materials, Applications and Nanostructures (ES)
- Ikerbasque (ES)
- Corresponding author
- Peña, Quim
- Wuttke, Stefan
- Lammers, Twan
- ORCID
- Venue
- Chemical Society Reviews
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2022
- Volume
- 51
- Issue
- 7
- Pages
- 2544-2582
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W4220985266
- Cited by
- 259
- References
- 441
- Citations by year
- 2026: 65 · 2025: 70 · 2024: 62 · 2023: 44 · 2022: 18
- FWCI
- 5.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Society Reviews (publishedVersion)
- PubMed (publishedVersion)
- RWTH Publications (RWTH Aachen) (submittedVersion)
- Funders
- H2020 European Research Council (ERC grant: Meta-Targeting (CoG 864121), PIcelles (PoC 813086))
- Deutsche Forschungsgemeinschaft (GRK 2375)
- Bundesministerium für Bildung und Forschung (16GW0319K)
- Topics
- Health Sciences › Medicine › Oncology › Metal complexes synthesis and properties
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Physical Sciences › Chemistry › Inorganic Chemistry › Metal-Organic Frameworks: Synthesis and Applications
- Keywords
- metal-based drugs, metal-based anticancer agents, nanomedicine, metal complexes, cisplatin, carboplatin, oxaliplatin, drug delivery, nanocarriers, coordination chemistry, drug resistance, pharmacokinetics, clinical translation, combination therapy with immunotherapy
- MeSH terms
- Antineoplastic Agents, Humans, Immunotherapy, Neoplasms, Nanomedicine, Coordination Complexes
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Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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