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Cited by 528

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Processes To Separate Enantiomers

Open access
Lorenz, Heike, Seidel‐Morgenstern, Andreas·2014·Angewandte Chemie International Edition

Abstract

The provision of pure enantiomers is of increasing importance not only for the pharmaceutical industry but also for agrochemistry and biotechnology. In general, there are two rival approaches to provide pure enantiomers. The “chiral” approach is based on developing an asymmetric synthesis of just one of the enantiomers, while the “racemic” approach is based on separating mixtures of the two enantiomers. In the last few years remarkable progress has been achieved in the latter area. This Review focuses in particular on enantioselective crystallization processes and preparative chromatography, including hybrid processes and the incorporation of racemization steps. Several examples from our research are used for illustration purposes.

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Crossref · 10.1002/anie.201302823

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Metadata

Authors
Lorenz, H., & Seidel‐Morgenstern, A.
Venue
Angewandte Chemie International Edition
Publisher
Wiley
Published
2014-01-17
Volume
53
Issue
5
Pages
1218-1250
ISSN
  • 1433-7851 (ISSN-L)
  • 1521-3773
OpenAlex
W2090545574
Cited by
528
References
6
FWCI
17.69
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Processes To Separate Enantiomers. https://app.cochat.ai/papers/10.1002/anie.201302823
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Lorenz, H., & Seidel‐Morgenstern, A. (2014). Processes To Separate Enantiomers. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201302823

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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