Paper‐Based Electrical Respiration Sensor
Open accessAbstract
Current methods of monitoring breathing require cumbersome, inconvenient, and often expensive devices; this requirement sets practical limitations on the frequency and duration of measurements. This article describes a paper‐based moisture sensor that uses the hygroscopic character of paper (i.e. the ability of paper to adsorb water reversibly from the surrounding environment) to measure patterns and rate of respiration by converting the changes in humidity caused by cycles of inhalation and exhalation to electrical signals. The changing level of humidity that occurs in a cycle causes a corresponding change in the ionic conductivity of the sensor, which can be measured electrically. By combining the paper sensor with conventional electronics, data concerning respiration can be transmitted to a nearby smartphone or tablet computer for post‐processing, and subsequently to a cloud server. This means of sensing provides a new, practical method of recording and analyzing patterns of breathing.
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Monitoring and analyzing exhaled breath (respiratory rate and composition) can achieve non-invasive early prevention and treatment of certain diseases.
“monitoring and analyzing information related to it, such as respiratory rate and composition of exhalation, can achieve the non-invasive and comfortable early prevention and treatment of certain diseases”
From Functionalized Hydrogel-Based Wearable Gas and Humidity Sensors. (2023) · cites this paper as [21]
Cites
Increased Prevalence of Sleep-Disordered Breathing in Adults
Peppard, P. E., Young, T., Barnet, J. H., Palta, M., Hagen, E. W., & Hla, K. M. (2013) · American Journal of Epidemiology · doi:10.1093/aje/kws342 · Cited by 4,618 · see citing works
Respiratory rate predicts cardiopulmonary arrest for internal medicine inpatients.
Fieselmann, J. F., Hendryx, M. S., Helms, C. M., & Wakefield, D. S. (1993) · Journal of General Internal Medicine · doi:10.1007/bf02600071 · Cited by 399 · see citing works
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End-to-end design of wearable sensors
Ates, H. C., Nguyen, P. Q., Gonzalez-Macia, L., Morales-Narváez, E., Güder, F., Collins, J. J., & Dincer, C. (2022) · Nature Reviews Materials · doi:10.1038/s41578-022-00460-x · Cited by 1,306 · see citing works
Self-citationFunctionalized Hydrogel-Based Wearable Gas and Humidity Sensors.
Luo, Y., Li, J., Ding, Q., Wang, H., Liu, C., & Wu, J. (2023) · Nano-Micro Letters · doi:10.1007/s40820-023-01109-2 · Cited by 236 · see citing works
“As human exhalation contains a large number of gas and water molecules, monitoring and analyzing information related to it, such as respiratory rate and composition of exhalation, can achieve the non-invasive and comfortable early prevention and treatment of certain diseases [21, 22].”
Background
- Authors
- Güder, F., Ainla, A., Redston, J., Mosadegh, B., Glavan, A., Martin, T. J., & Whitesides, G. M.
- Affiliations
- Harvard University (US)
- Corresponding author
- Whitesides, George M.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2016-04-05
- Volume
- 55
- Issue
- 19
- Pages
- 5727-5732
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2332542316
- Cited by
- 472
- References
- 2
- Citations by year
- 2026: 28 · 2025: 45 · 2024: 48 · 2023: 52 · 2022: 61 · 2021: 59 · 2020: 54 · 2019: 65 · 2018: 31 · 2017: 24 · 2016: 5
- FWCI
- 20.09
- Type
- journal article
- Language
- en
- Open access
- green
- nrs.harvard.edu
- Locations
- Angewandte Chemie International Edition (publishedVersion)
- PubMed (publishedVersion)
- Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
- Spiral (Imperial College London) (submittedVersion)
- Funders
- DTRA (HDTRA1-14-C-0037)
- German Research Foundation
- DFG (GU 1468/1-1)
- Swedish Research Council
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Biosensors and Analytical Detection
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Keywords
- paper-based sensors, respiratory monitoring, respiratory rate, humidity sensing, ionic conductivity, paper-based electronics, smartphone data transmission, cloud server, wearable sensors
- MeSH terms
- Smartphone, Electricity, Humans, Humidity, Monitoring, Physiologic, Paper, Respiration, Signal Processing, Computer-Assisted, Exercise, Wireless Technology
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