The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
A Dual‐Targeted Organic Photothermal Agent for Enhanced Photothermal Therapy
Abstract
The development of highly effective anticancer drugs that cause minimal damage to the surrounding normal tissues is a challenging topic in cancer therapy. Herein, we demonstrate a dual‐targeted organic molecule that functions as a photothermal agent by actively targeting tumor tissue and mitochondria to selectively kill cancer cells. The synthesized photothermal agent exhibited high photothermal conversion efficiency, low cytotoxicity, and good biological compatibility. In vivo experiments showed an excellent tumor inhibitory effect of the dual‐targeted photothermal agent.
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Cites
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Cited by
Shen, J., Karges, J., Xiong, K., Chen, Y., Ji, L., & Chao, H. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120979 · Cited by 130
Synergy of hypoxia relief and heat shock protein inhibition for phototherapy enhancement
Zhang, G., Cheng, W., Du, L., Xu, C., & Li, J. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-020-00749-5 · Cited by 95
Mitochondria targeted fluorogenic theranostic agents for cancer therapy
Singh, H., Sareen, D., George, J. M., Bhardwaj, V., Rha, H., Lee, S. J., Sharma, S., Sharma, A., & Kim, J. S. (2022) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2021.214283 · Cited by 72
Yu, J.-F., Li, J., & Li, M. (2024) · ACS Sensors · doi:10.1021/acssensors.4c00561 · Cited by 16
Metadata
- Authors
- Wang, H., Chang, J., Shi, M., Pan, W., Li, N., & Tang, B.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2018-12-20
- Volume
- 58
- Issue
- 4
- Pages
- 1057-1061
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2900151934
- Cited by
- 325
- References
- 32
- FWCI
- 12.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Funders
- National Natural Science Foundation of China (21535004, 91753111, 21874086, 21602125, 21390411)
- Natural Science Foundation of Shandong Province (ZR2016BQ38)
- Postdoctoral Research Foundation of China (40411585)
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- Wang, H., Chang, J., Shi, M., Pan, W., Li, N., & Tang, B. (2019). A Dual‐Targeted Organic Photothermal Agent for Enhanced Photothermal Therapy. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201811273
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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