The Role of Organoferrates in Iron‐Catalyzed Cross‐Couplings
Abstract
Recent groundbreaking studies on organoferrates have demonstrated that coordinatively unsaturated three-coordinate-σ-alkylferrates are active catalysts in Fe-catalyzed cross-couplings with Grignard reagents and that pronounced solvent and counterion effects dictate metalate speciation and catalyst activity. Thanks to modern spectroscopic methods, sensitive catalyst intermediates could be analyzed.
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Addition of N-methyl pyrrolidone (NMP), a cyclic tertiary amide, has been shown to enhance the catalytic activity of iron in cross-coupling reactions which enables the formation of catalytically active monomeric ferrates by coordination.
“In fact, the addition of N-methyl pyrrolidone (NMP), a cyclic tertiary amide, has been shown to enhance the catalytic activity of iron in cross-coupling reactions which enables the formation of catalytically active monomeric ferrates by coordination.70–73”
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Kirchhecker, S., Nguyen, N., Reichert, S., Lützow, K., Eselem Bungu, P. S., Jacobi von Wangelin, A., Sandl, S., & Neffe, A. T. (2023) · RSC Advances · doi:10.1039/d3ra03112h · Cited by 6 · see citing works
Self-citation
- Authors
- Sandl, S., & Jacobi von Wangelin, A.
- Affiliations
- Universität Hamburg (DE)
- Department of Chemistry University of Hamburg Martin Luther King Platz 6 20146 Hamburg Germany
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2020-01-30
- Volume
- 59
- Issue
- 14
- Pages
- 5434-5437
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W3004116745
- Cited by
- 18
- References
- 53
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 2 · 2022: 1 · 2021: 6 · 2020: 2
- FWCI
- 0.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Angewandte Chemie International Edition (publishedVersion)
- PubMed (publishedVersion)
- Funders
- H2020 European Research Council (CoG 683150)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Catalytic Cross-Coupling Reactions
- Physical Sciences › Chemistry › Organic Chemistry › Coordination Chemistry and Organometallics
- Physical Sciences › Chemistry › Organic Chemistry › Organometallic Complex Synthesis and Catalysis
- Keywords
- iron catalysis, cross-coupling reactions, Grignard reagents, solvent effects, counterion effects, catalytic intermediates, coordination chemistry
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