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The influence of temperature on the solubility of monosodium urate
Abstract
The limited solubility of monosodium urate in the presence of physiological sodium concentrations is shown to fall sharply with decreasing temperature. It is suggested that this phenomenon may play a role in determining the clinically observed distribution of tophi and the susceptibility of certain joints to acute gouty arthritis.
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Cited by
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Shi, Y., Evans, J. E., & Rock, K. L. (2003) · Nature · doi:10.1038/nature01991 · Cited by 1,684
Febuxostat Compared with Allopurinol in Patients with Hyperuricemia and Gout
Becker, M. A., Schumacher, H. R., Wortmann, R. L., MacDonald, P. A., Eustace, D., Palo, W. A., Streit, J., & Joseph-Ridge, N. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050373 · Cited by 1,357
Schumacher, H. R., Becker, M. A., Wortmann, R. L., MacDonald, P. A., Hunt, B., Streit, J., Lademacher, C., & Joseph‐Ridge, N. (2008) · Arthritis Care & Research · doi:10.1002/art.24209 · Cited by 638
New insights into purine metabolism in metabolic diseases: role of xanthine oxidoreductase activity
Furuhashi, M. (2020) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00378.2020 · Cited by 361
Hyperuricemia and Gout: Classification, Complications and Management
Boss, G. R., & Seegmiller, J. E. (1979) · New England Journal of Medicine · doi:10.1056/nejm197906283002604 · Cited by 281
Metadata
- Authors
- Loeb, J. N.
- Venue
- Arthritis & Rheumatism
- Publisher
- Wiley
- Published
- 1972-03
- Volume
- 15
- Issue
- 2
- Pages
- 189-192
- ISSN
- 0004-3591 (ISSN-L)
- 1529-0131
- OpenAlex
- W2044862535
- Cited by
- 337
- References
- 0
- FWCI
- 2.18
- Type
- journal article
- Language
- en
- Open access
- closed
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- Loeb, J. N. (1972). The influence of temperature on the solubility of monosodium urate. Arthritis & Rheumatism. https://doi.org/10.1002/art.1780150209
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.