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Antigen‐induced arthritis in mice
Abstract
Antigen‐induced arthritis was established in the mouse by immunization with methylated bovine serum albumin (mBSA) in complete Freund's adjuvant with B pertussis vaccine. The knee joint was injected after 21 days with mBSA in saline. The arthritis was chronic, antigen‐specific, and T‐cell dependent in hypothymic nu/nu mice. C57BL and BALB/c mice were susceptible, whereas CBA mice were relatively resistant. Susceptibility was dominant; one gene was loosely linked to the “b” allele of the H‐2 complex of C57BL mice.
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Citations
Cited by
Huehn, J., Siegmund, K., Lehmann, J. C. U., Siewert, C., Haubold, U., Feuerer, M., Debes, G. F., Lauber, J., Frey, O., Przybylski, G. K., et al. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20031562 · Cited by 624
Autoimmune disease: why and where it occurs
Marrack, P., Kappler, J., & Kotzin, B. L. (2001) · Nature Medicine · doi:10.1038/90935 · Cited by 609
Interleukin 6 plays a key role in the development of antigen-induced arthritis
Ohshima, S., Saeki, Y., Mima, T., Sasai, M., Nishioka, K., Nomura, S., Kopf, M., Katada, Y., Tanaka, T., Suemura, M., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.14.8222 · Cited by 406
Animal models of arthritis: relevance to human disease.
Bendele, A., Mccomb, J., Gould, T., Mcabee, T., Sennello, G., Chlipala, E., & Guy, M. (1999) · Toxicologic Pathology · doi:10.1177/019262339902700125 · Cited by 293
Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells
Rauber, S., Luber, M., Weber, S., Maul, L., Soare, A., Wohlfahrt, T., Lin, N.-Y., Dietel, K., Bozec, A., Herrmann, M., et al. (2017) · Nature Medicine · doi:10.1038/nm.4373 · Cited by 282
Metadata
- Authors
- Brackertz, D., Mitchell, G. F., & Mackay, I. R.
- Venue
- Arthritis & Rheumatism
- Publisher
- Wiley
- Published
- 1977-04
- Volume
- 20
- Issue
- 3
- Pages
- 841-850
- ISSN
- 0004-3591 (ISSN-L)
- 1529-0131
- OpenAlex
- W2005769835
- Cited by
- 339
- References
- 0
- FWCI
- 3.87
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Antigen‐induced arthritis in mice. https://app.cochat.ai/papers/10.1002/art.1780200314
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- Brackertz, D., Mitchell, G. F., & Mackay, I. R. (1977). Antigen‐induced arthritis in mice. Arthritis & Rheumatism. https://doi.org/10.1002/art.1780200314
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
