The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Restricted subpopulations of DNA antibodies in kidneys of mice with systemic lupus
Abstract
Sera from MRL/1, BXSB, and NZB/NZW mice, which develop IgG antibodies to DNA and glomerular deposits of DNA‐antiDNA immune complexes, were studied by isoelectric focusing. A large array of IgG antibodies with isoelectric points ranging from pH 5.5‐9.0 were found to bind double‐stranded DNA. Antibodies with isoelectric points from 8.0‐8.5 were significantly more frequent than antibodies focusing in all other pH ranges. In contrast, glomerular eluates from MRL/1 and NZB/NZW mice contained a restricted number of DNA‐binding bands, all of which focused at pH 8.0‐9.0. Anti‐DNA with isoelectric points from pH 8.0‐9.0 may be more pathogenic for the kidney than other subpopulations.
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Citations
Cites
Complement fixation with cell nuclei and DNA in lupus erythematosus
Robbins, W. C., Holman, H. R., Deicher, H., & Kunkel, H. G. (1957) · Experimental Biology and Medicine · doi:10.3181/00379727-96-23545 · Cited by 302
Antibodies to native and denatured deoxyribonucleic acid in systemic lupus erythematosus
Arana, R., & Seligmann, M. (1967) · Journal of Clinical Investigation · doi:10.1172/jci105677 · Cited by 158
Cited by
Anti-dsDNA: choice of assay in relation to clinical value
Smeenk, R. J. T., van den Brink, H. G., Brinkman, K., Termaat, R. M., Berden, J. H. M., & Swaak, A. J. G. (1991) · Rheumatology International · doi:10.1007/bf00304496 · Cited by 75
Metadata
- Authors
- Ebling, F., & Hahn, B. H.
- Venue
- Arthritis & Rheumatism
- Publisher
- Wiley
- Published
- 1980-04
- Volume
- 23
- Issue
- 4
- Pages
- 392-403
- ISSN
- 0004-3591 (ISSN-L)
- 1529-0131
- OpenAlex
- W1994306491
- Cited by
- 265
- References
- 2
- FWCI
- 10.54
- Type
- journal article
- Language
- en
- Open access
- closed
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