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Cited by 241

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Histopathology of the rheumatoid lesion

Bromley, Michael, Woolley, David E.·1984·Arthritis & Rheumatism

Abstract

Histochemical and ultrastructural techniques were used to examine the cartilage—pannus junction of 49 rheumatoid joints. Whereas 24 showed relatively acellular, fibrous pannus tissue, 25 demonstrated “cellular” junctions with different cell types at sites of erosion. Macrophages and fibroblasts were commonly observed as majority cell types in most specimens, but others showed mast cells, polymorphonuclear leukocytes, dendritic, or plasma cells as the predominant cell type. Some showed local accumulations of different cell types at sites along each junction. Our findings show that the cellular composition at sites of cartilage erosion varies greatly and suggest that cells are subject to turnover and interchange.

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Metadata

Authors
Bromley, M., & Woolley, D. E.
Venue
Arthritis & Rheumatism
Publisher
Wiley
Published
1984-08
Volume
27
Issue
8
Pages
857-863
ISSN
  • 0004-3591 (ISSN-L)
  • 1529-0131
OpenAlex
W2030728818
Cited by
241
References
0
FWCI
11.35
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Histopathology of the rheumatoid lesion. https://app.cochat.ai/papers/10.1002/art.1780270804
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Bromley, M., & Woolley, D. E. (1984). Histopathology of the rheumatoid lesion. Arthritis & Rheumatism. https://doi.org/10.1002/art.1780270804

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.