Hypothalamic–pituitary–adrenal axis perturbations in patients with fibromyalgia

Crofford, Leslie J.; Pillemer, Stanley R.; Kalogeras, Konstantine T.; Cash, Joseph M.; Michelson, David; Kling, Mitchel A.; Sternberg, Esther M.; Gold, Philip W.; Chrousos, George P.; Wilder, Ronald L.

doi:10.1002/art.1780371105

Hypothalamic–pituitary–adrenal axis perturbations in patients with fibromyalgia

Objective To examine basal and stimulated hypothalamic-pituitary-adrenal (HPA) axis and related hormone levels, including adrenocorticotropin (ACTH), cortisol, arginine vasopressin (AVP), and neuropeptide Y (NPY), in patients with fibromyalgia (FM). Methods Basal and ovine corticotropin-releasing…