The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Antioxidant and antibacterial activities of eugenol and carvacrol‐grafted chitosan nanoparticles
Abstract
Essential oils are known to possess antimicrobial and antioxidant activity while chitosan is a biocompatible polymer with antibacterial activity against a broad spectrum of bacteria. In this work, nanoparticles with both antioxidant and antibacterial properties were prepared by grafting eugenol and carvacrol (two components of essential oils) on chitosan nanoparticles. Aldehyde groups were first introduced in eugenol and carvacrol, and the grafting of these oils to chitosan nanoparticles was carried out via the Schiff base reaction. The surface concentration of the grafted essential oil components was determined by X‐ray photoelectron spectroscopy (XPS). The antioxidant activities of the carvacrol‐grafted chitosan nanoparticles (CHCA NPs) and the eugenol‐grafted chitosan nanoparticles (CHEU NPs) were assayed with diphenylpicrylhydrazyl (DPPH). Antibacterial assays were carried out with a representative gram‐negative bacterium, Escherichia coli (E. coli) and a gram‐positive bacterium, Staphylococcus aureus (S. aureus). The grafted eugenol and carvacrol conferred antioxidant activity to the chitosan nanoparticles, and the essential oil component‐grafted chitosan nanoparticles achieved an antibacterial activity equivalent to or better than that of the unmodified chitosan nanoparticles. Cytotoxicity assays using 3T3 mouse fibroblast showed that the cytotoxicity of CHEU NPs and CHCA NPs were significant lower than those of the pure essential oils. Biotechnol. Bioeng. 2009; 104: 30–39 © 2009 Wiley Periodicals, Inc.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Mosmann, T. (1983) · Journal of Immunological Methods · doi:10.1016/0022-1759(83)90303-4 · Cited by 56,104
Essential oils: Their antibacterial properties and potential applications in foods—A review
Burt, S. (2004) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2004.03.022 · Cited by 10,488
Chitin and chitosan: Properties and applications
Rinaudo, M. (2006) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2006.06.001 · Cited by 8,259
Biological effects of essential oils—A review
Bakkali, F., Averbeck, S., Averbeck, D., & Idaomar, M. (2008) · Food and Chemical Toxicology · doi:10.1016/j.fct.2007.09.106 · Cited by 7,929
Chitosan as antimicrobial agent: applications and mode of action.
Rabea, E. I., Badawy, M. E.-T., Stevens, C. V., Smagghe, G., & Steurbaut, W. (2003) · Biomacromolecules · doi:10.1021/bm034130m · Cited by 3,123
Chitosan Chemistry and Pharmaceutical Perspectives
Kumar, M. N. V. R., Muzzarelli, R. A. A., Muzzarelli, C., Sashiwa, H., & Domb, A. J. (2004) · Chemical Reviews · doi:10.1021/cr030441b · Cited by 2,938
Antibacterial and Antifungal Properties of Essential Oils
Kalemba, D., & Kunicka, A. (2003) · Current Medicinal Chemistry · doi:10.2174/0929867033457719 · Cited by 1,933
Food applications of chitin and chitosans
Shahidi, F., Arachchi, J. K. V., & Jeon, Y.-J. (1999) · Trends in Food Science & Technology · doi:10.1016/s0924-2244(99)00017-5 · Cited by 1,826
Preparation and antibacterial activity of chitosan nanoparticles
Qi, L., Xu, Z., Jiang, X., Hu, C., & Zou, X. (2004) · Carbohydrate Research · doi:10.1016/j.carres.2004.09.007 · Cited by 1,804
Antibacterial action of chitosan and carboxymethylated chitosan
Fei Liu, X., Lin Guan, Y., Zhi Yang, D., Li, Z., & De Yao, K. (2001) · Journal of Applied Polymer Science · doi:10.1002/1097-4628(20010214)79:7<1324::aid-app210>3.0.co;2-l · Cited by 1,178
Cited by
Allahverdiyev, A. M., Kon, K. V., Abamor, E. S., Bagirova, M., & Rafailovich, M. (2011) · Expert Review of Anti-infective Therapy · doi:10.1586/eri.11.121 · Cited by 411
Use of botanical insecticides for sustainable agriculture: Future perspectives
Campos, E. V. R., Proença, P. L. F., Oliveira, J. L., Bakshi, M., Abhilash, P. C., & Fraceto, L. F. (2019) · Ecological Indicators · doi:10.1016/j.ecolind.2018.04.038 · Cited by 412
Preparation and characterization of clove essential oil-loaded liposomes
Sebaaly, C., Jraij, A., Fessi, H., Charcosset, C., & Greige-Gerges, H. (2015) · Food Chemistry · doi:10.1016/j.foodchem.2015.01.067 · Cited by 291
Nair, H. B., Sung, B., Yadav, V. R., Kannappan, R., Chaturvedi, M. M., & Aggarwal, B. B. (2010) · Biochemical Pharmacology · doi:10.1016/j.bcp.2010.07.021 · Cited by 269
Khezripour, A. R., Souri, D., Tavafi, H., & Ghabooli, M. (2019) · Measurement · doi:10.1016/j.measurement.2019.106939 · Cited by 21
Metadata
- Authors
- Chen, F., Shi, Z., Neoh, K. G., & Kang, E. T.
- Venue
- Biotechnology and Bioengineering
- Publisher
- Wiley
- Published
- 2009-04-30
- Volume
- 104
- Issue
- 1
- Pages
- 30-39
- ISSN
- 0006-3592 (ISSN-L)
- 1097-0290
- OpenAlex
- W2099397182
- Cited by
- 262
- References
- 48
- FWCI
- 2.32
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Antioxidant and antibacterial activities of eugenol and carvacrol‐grafted chitosan nanoparticles. https://app.cochat.ai/papers/10.1002/bit.22363
- The paper
- Chen, F., Shi, Z., Neoh, K. G., & Kang, E. T. (2009). Antioxidant and antibacterial activities of eugenol and carvacrol‐grafted chitosan nanoparticles. Biotechnology and Bioengineering. https://doi.org/10.1002/bit.22363
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
