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Alginate as immobilization material: III. Diffusional properties
Abstract
The rate of diffusion of serum albumin (MW 6.9 · 10 4 D) out of beads of calcium alginate gels depends upon the concentration and uronic acid composition of the alginate (ManA/GulA ratio), the conditions under which the beads are produced, the pH, and the temperature. The diffusion coefficient decreases with increasing alginate concentration, and (ManA/GulA) ratio and with decreasing pH. Diffusion out of the beads, in which the alginate is uniformly distributed (homogeneous gel), is faster than out of the beads in which the alginate is concentrated at the surface (inhomogeneous gel). The temperature dependence of the diffusion coefficient follows the Arrhenius law, with an activation energy of ∼23 kJ · mol−1.
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Cited by
Alginate Composition Effects on a Neural Stem Cell–Seeded Scaffold
Purcell, E. K., Singh, A., & Kipke, D. R. (2009) · Tissue Engineering Part C: Methods · doi:10.1089/ten.tec.2008.0302 · Cited by 95
Metadata
- Authors
- Martinsen, A., Storrø, I., & Skjårk‐Bræk, G.
- Venue
- Biotechnology and Bioengineering
- Publisher
- Wiley
- Published
- 1992-01-20
- Volume
- 39
- Issue
- 2
- Pages
- 186-194
- ISSN
- 0006-3592 (ISSN-L)
- 1097-0290
- OpenAlex
- W2040333793
- Cited by
- 274
- References
- 0
- FWCI
- 3.51
- Type
- journal article
- Language
- en
- Open access
- closed
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- Martinsen, A., Storrø, I., & Skjårk‐Bræk, G. (1992). Alginate as immobilization material: III. Diffusional properties. Biotechnology and Bioengineering. https://doi.org/10.1002/bit.260390210
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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