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Coeliac plexus block for pain in pancreatic cancer and chronic pancreatitis
Abstract
We have performed coeliac plexus block by standard percutaneous technique for disabling pain in 36 patients (13 with cancer and 23 with chronic pancreatitis). Eleven of the 13 cancer patients had complete pain relief initially and 7 remained pain free at the time of death. By contrast, only 12 of the 23 patients with pancreatitis had complete pain relief, 6 had partial relief and there was no effect in 5. The mean pain-free period in the chronic pancreatitis patients was only 2 months, and the longest 4 months. Benefit was least in patients with previous pancreatic surgery and repeat blocks were unhelpful. Transient postural hypotension occurred in most patients; two had nerve root pain and one developed persistent weakness and anaesthesia of the left leg, with bladder disturbance. These results warrant the continuing use of coeliac plexus block in pancreatic cancer, but rarely in chronic pancreatitis.
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Cited by
Lillemoe, K. D., Cameron, J. L., Kaufman, H. S., Yeo, C. J., Pitt, H. A., & Sauter, P. K. (1993) · Annals of Surgery · doi:10.1097/00000658-199305010-00004 · Cited by 549
Steer, M. L., Waxman, I., & Freedman, S. (1995) · New England Journal of Medicine · doi:10.1056/nejm199506013322206 · Cited by 543
Pain mechanisms in chronic pancreatitis: of a master and his fire.
Demir, I. E., Tieftrunk, E., Maak, M., Friess, H., & Ceyhan, G. O. (2011) · Langenbeck s Archives of Surgery · doi:10.1007/s00423-010-0731-1 · Cited by 101
Pancreatic enzyme pharmacotherapy
Ferrone, M., Raimondo, M., & Scolapio, J. S. (2007) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.27.6.910 · Cited by 88
Metadata
- Authors
- Leung, J. W. C., Bowen-Wright, M., Aveling, W., Shorvon, P. J., & Cotton, P. B.
- Venue
- Journal of British Surgery
- Publisher
- Oxford University Press (OUP)
- Published
- 1983-12-01
- Volume
- 70
- Issue
- 12
- Pages
- 730-732
- ISSN
- 0007-1323 (ISSN-L)
- 1365-2168
- OpenAlex
- W1996636764
- Cited by
- 166
- References
- 0
- FWCI
- 1.71
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Coeliac plexus block for pain in pancreatic cancer and chronic pancreatitis. https://app.cochat.ai/papers/10.1002/bjs.1800701212
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- Leung, J. W. C., Bowen-Wright, M., Aveling, W., Shorvon, P. J., & Cotton, P. B. (1983). Coeliac plexus block for pain in pancreatic cancer and chronic pancreatitis. Journal of British Surgery. https://doi.org/10.1002/bjs.1800701212
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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