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Cited by 284

The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.

Final follow-up of the Multicentre Aneurysm Screening Study (MASS) randomized trial of abdominal aortic aneurysm screening

Open access
Thompson, S G, Ashton, H A, Gao, L, Buxton, M J, Scott, R A P·2012·British Journal of Surgery

Abstract

Background: The long-term effects of abdominal aortic aneurysm (AAA) screening were investigated in extended follow-up from the UK Multicentre Aneurysm Screening Study (MASS) randomized trial. Methods: A population-based sample of men aged 65–74 years were randomized individually to invitation to ultrasound screening (invited group) or to a control group not offered screening. Patients with an AAA (3·0 cm or larger) detected at screening underwent surveillance and were offered surgery after predefined criteria had been met. Cause-specific mortality data were analysed using Cox regression. Results: Some 67 770 men were enrolled in the study. Over 13 years, there were 224 AAA-related deaths in the invited group and 381 in the control group, a 42 (95 per cent confidence interval 31 to 51) per cent reduction. There was no evidence of effect on other causes of death, but there was an overall reduction in all-cause mortality of 3 (1 to 5) per cent. The degree of benefit seen in earlier years of follow-up was slightly diminished by the occurrence of AAA ruptures in those with an aorta originally screened normal. About half of these ruptures had a baseline aortic diameter in the range 2·5–2·9 cm. It was estimated that 216 men need to be invited to screening to save one death over the next 13 years. Conclusion: Screening resulted in a reduction in all-cause mortality, and the benefit in AAA-related mortality continued to accumulate throughout follow-up. Registration number: ISRCTN37381646 (http://www.controlled-trials.com).

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Metadata

Authors
Thompson, S. G., Ashton, H. A., Gao, L., Buxton, M. J., & Scott, R. A. P.
Venue
British Journal of Surgery
Published
2012-10-03
Volume
99
Issue
12
Pages
1649-1656
ISSN
  • 0007-1323 (ISSN-L)
  • 1365-2168
OpenAlex
W2143211325
Cited by
284
References
16
FWCI
17.08
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Final follow-up of the Multicentre Aneurysm Screening Study (MASS) randomized trial of abdominal aortic aneurysm screening. https://app.cochat.ai/papers/10.1002/bjs.8897
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Thompson, S. G., Ashton, H. A., Gao, L., Buxton, M. J., & Scott, R. A. P. (2012). Final follow-up of the Multicentre Aneurysm Screening Study (MASS) randomized trial of abdominal aortic aneurysm screening. British Journal of Surgery. https://doi.org/10.1002/bjs.8897

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.