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Cited by 191

The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

From Interstellar Amino Acids to Prebiotic Catalytic Peptides: A Review

Brack, André·2007·Chemistry & Biodiversity

Abstract

Amino acids were most likely available on the primitive Earth, produced in the primitive atmosphere or in hydrothermal vents. Import of extraterrestrial amino acids may have represented the major supply, as suggested by micrometeorite collections and simulation experiments in space and in the laboratory. Selective condensation of amino acids in water has been achieved via N‐carboxy anydrides. Homochiral peptides with an alternating sequence of hydrophobic and hydrophilic amino acids adopt stereoselective and thermostable β‐pleated sheet structures. Some of the homochiral β‐sheets strongly accelerate the hydrolysis of oligoribonucleotides. The β‐sheet‐forming peptides have also been shown to protect their amino acids from racemization. Even if peptides are not able to self‐replicate, i.e., to replicate a complete sequence from the mixture of amino acids, the accumulation of chemically active peptides on the primitive Earth appears plausible via thermostable and stereoselective β‐sheets made of alternating sequences.

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Metadata

Authors
Brack, A.
Venue
Chemistry & Biodiversity
Publisher
Wiley
Published
2007-04
Volume
4
Issue
4
Pages
665-679
ISSN
  • 1612-1872 (ISSN-L)
  • 1612-1880
OpenAlex
W2015254588
Cited by
191
References
14
FWCI
6.24
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: From Interstellar Amino Acids to Prebiotic Catalytic Peptides: A Review. https://app.cochat.ai/papers/10.1002/cbdv.200790057
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Brack, A. (2007). From Interstellar Amino Acids to Prebiotic Catalytic Peptides: A Review. Chemistry & Biodiversity. https://doi.org/10.1002/cbdv.200790057

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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