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Cited by 534

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Antibacterial Mechanism of Curcumin: A Review

Zheng, Dantong, Huang, Chongxing, Huang, Haohe, Zhao, Yuan, Khan, Muhammad Rafi Ullah, Zhao, Hui, Huang, Lijie·2020·Chemistry & Biodiversity

Abstract

Curcumin is a plant‐derived polyphenolic active substance with broad‐spectrum antibacterial properties. Curcumin blocks bacterial growth owing to its structural characteristics and the generation of antioxidation products. Curcumin can inhibit bacterial virulence factors, inhibit bacterial biofilm formation and prevent bacterial adhesion to host receptors through the bacterial quorum sensing regulation system. As a photosensitizer, curcumin acts under blue light irradiation to induce phototoxicity and inhibit bacterial growth. Moreover, it can exert a synergistic antibacterial effect with other antibacterial substances. In this review, we summarize the research progress on the antibacterial mechanism of curcumin based on five targeting structures and two modes of action. Our discussion provides a theoretical basis and technical foundation for the development and application of natural antibacterial agents.

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Metadata

Authors
Zheng, D., Huang, C., Huang, H., Zhao, Y., Khan, M. R. U., Zhao, H., & Huang, L.
Venue
Chemistry & Biodiversity
Publisher
Wiley
Published
2020-07-27
Volume
17
Issue
8
Pages
e2000171-e2000171
ISSN
  • 1612-1872 (ISSN-L)
  • 1612-1880
OpenAlex
W3034741772
Cited by
534
References
2
FWCI
16.10
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Antibacterial Mechanism of Curcumin: A Review. https://app.cochat.ai/papers/10.1002/cbdv.202000171
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Zheng, D., Huang, C., Huang, H., Zhao, Y., Khan, M. R. U., Zhao, H., & Huang, L. (2020). Antibacterial Mechanism of Curcumin: A Review. Chemistry & Biodiversity. https://doi.org/10.1002/cbdv.202000171

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