The DOI matches its Crossref record.
Electrospray Mass Spectrometry of Poly(propylene imine) Dendrimers—The Issue of Dendritic Purity or Polydispersity
Open accessAbstract
Electrospray mass spectrometry (ESI‐MS) is used to analyze in detail the structure of the first five generations of the poly(propylene imine) dendrimers with 4–64 end groups. Although the reaction sequence to prepare these dendrimers is highly optimized, an accumulation of statistical defects is observed at higher generations. A simple statistical simulation allows the assignment of all peaks in the deconvoluted spectrum and the determination of yields for each side reaction in the formation of each generation. The fifth generation of the poly(propylene imine) dendrimer containing amine end groups, which is formed after 248 consecutive reaction steps, possesses a dendritic purity of approx. 20%, which corresponds to a polydispersity of approximately 1.002. The defects in the divergent growth patterns of dendrimers are compared to those observed in the Merrifield synthesis of polypeptides.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
About Dendrimers: Structure, Physical Properties, and Applications
Bosman, A. W., Janssen, H. M., & Meijer, E. W. (1999) · Chemical Reviews · doi:10.1021/cr970069y · Cited by 2,343
Self-citationTomalia, D. A. (2005) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2005.01.007 · Cited by 1,115
Villaraza, A. J. L., Bumb, A., & Brechbiel, M. W. (2010) · Chemical Reviews · doi:10.1021/cr900232t · Cited by 632
Chen, C. Z., Beck-Tan, N. C., Dhurjati, P., van Dyk, T. K., LaRossa, R. A., & Cooper, S. L. (2000) · Biomacromolecules · doi:10.1021/bm0055495 · Cited by 443
Design and synthesis of glycodendrimers
Turnbull, W. B., & Stoddart, J. F. (2002) · Reviews in Molecular Biotechnology · doi:10.1016/s1389-0352(01)00062-9 · Cited by 262
Metadata
- Authors
- Hummelen, J. C., Van Dongen, J. L. J., & Meijer, E. W.
- Venue
- Chemistry – A European Journal
- Publisher
- Wiley
- Published
- 1997-09
- Volume
- 3
- Issue
- 9
- Pages
- 1489-1493
- ISSN
- 0947-6539 (ISSN-L)
- 1521-3765
- OpenAlex
- W2017526973
- Cited by
- 176
- References
- 0
- FWCI
- 17.00
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Electrospray Mass Spectrometry of Poly(propylene imine) Dendrimers—The Issue of Dendritic Purity or Polydispersity. https://app.cochat.ai/papers/10.1002/chem.19970030916
- The paper
- Hummelen, J. C., Van Dongen, J. L. J., & Meijer, E. W. (1997). Electrospray Mass Spectrometry of Poly(propylene imine) Dendrimers—The Issue of Dendritic Purity or Polydispersity. Chemistry – A European Journal. https://doi.org/10.1002/chem.19970030916
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
