Birth of a new macromolecular architecture: dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry.
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Targeted delivery by dendrimers can be achieved by attaching target ligands such as transferrin family ligands, monoclonal antibodies against specific receptors, and lectins such as wheat germ agglutinin.
“Targeted delivery by dendrimers can be achieve by attaching target ligands such as transferrin family ligands having an affinity for TRs, mAbs against specific receptors, lectins such as wheat germ agglutinin (WGA), etc”
From Nanotechnology: A Promising Approach for Delivery of Neuroprotective Drugs (2020) · cites this paper as Tomalia, 2005
Dendrimers are preferred over traditional polymers due to high aqueous solubility, biocompatibility, polyvalency, and precise molecular weight, making them amenable for targeted brain drug delivery.
“dendrimers are given more preference over traditional polymers due to various features such as high aqueous solubility, biocompatibility, polyvalency, and precise molecular weight which make them amenable for targeted drug delivery in the brain”
From Nanotechnology: A Promising Approach for Delivery of Neuroprotective Drugs (2020) · cites this paper as Tomalia, 2005
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“Targeted delivery by dendrimers can be achieve by attaching target ligands such as transferrin family ligands having an affinity for TRs, mAbs against specific receptors, lectins such as wheat germ agglutinin (WGA), etc (Tomalia, 2005).”
BackgroundOliveira, J. M., Salgado, A. J., Sousa, N., Mano, J. F., & Reis, R. L. (2010) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2010.04.006 · Cited by 182 · see citing works
Wang, J., & Dong, C. (2006) · Macromolecular Chemistry and Physics · doi:10.1002/macp.200500546 · Cited by 76 · see citing works
- Authors
- Tomalia, D. A.
- Affiliations
- Central Michigan University (US)
- Corresponding author
- Tomalia, Donald A.
- ORCID
- Tomalia, Donald A.
- Venue
- Progress in Polymer Science
- Publisher
- Elsevier BV
- Published
- 2005-03
- Volume
- 30
- Issue
- 3-4
- Pages
- 294-324
- ISSN
- 0079-6700 (ISSN-L)
- OpenAlex
- W1980627211
- Cited by
- 1,115
- References
- 117
- Citations by year
- 2026: 18 · 2025: 27 · 2024: 31 · 2023: 22 · 2022: 45 · 2021: 52 · 2020: 42 · 2019: 35 · 2018: 39 · 2017: 54 · 2016: 65 · 2015: 67 · 2014: 65 · 2013: 76 · 2012: 92
- FWCI
- 50.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Progress in Polymer Science (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Polymers and Plastics › Dendrimers and Hyperbranched Polymers
- Physical Sciences › Chemistry › Organic Chemistry › Advanced Polymer Synthesis and Characterization
- Physical Sciences › Chemistry › Organic Chemistry › Supramolecular Chemistry and Complexes
- Keywords
- dendrimers, dendrons, macromolecular architecture, monodispersity, protein mimicry, autoreactivity, nanotechnology
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