The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Illuminating Zinc in Biological Systems
Abstract
Zinc is the second most abundant transition metal in the human body, fulfilling a multitude of biological roles, but the mechanisms underlying its physiology are poorly understood. The lack of knowledge is, in part, due to the hitherto limited techniques available to track zinc in biological systems. The recent emergence of a number of zinc‐specific molecular sensors has provided a new tool to image zinc in live cells and tissue samples. This contribution highlights the concepts behind using zinc‐specific fluorescent molecular sensors to gain information about zinc action in biological samples, and provides representative examples of images recorded.
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Cites
Femtomolar Sensitivity of Metalloregulatory Proteins Controlling Zinc Homeostasis
Outten, C. E., & O'Halloran, A. T. V. (2001) · Science · doi:10.1126/science.1060331 · Cited by 1,489
Cited by
Small-Molecule Fluorescent Sensors for Investigating Zinc Metalloneurochemistry
Nolan, E. M., & Lippard, S. J. (2009) · Accounts of Chemical Research · doi:10.1021/ar8001409 · Cited by 620
Liu, T., Liu, D., Qu, F., Wang, D., Zhang, L., Ge, R., Hao, S., Ma, Y., Du, G., Asiri, A. M., et al. (2017) · Advanced Energy Materials · doi:10.1002/aenm.201700020 · Cited by 601
Zhao, Y., Zhang, X.-B., Han, Z.-X., Qiao, L., Li, C.-Y., Jian, L.-X., Shen, G.-L., & Yu, R.-Q. (2009) · Analytical Chemistry · doi:10.1021/ac901127n · Cited by 455
The Design of Inhibitors for Medicinally Relevant Metalloproteins
Jacobsen, F. E., Lewis, J. A., & Cohen, S. M. (2007) · ChemMedChem · doi:10.1002/cmdc.200600204 · Cited by 132
Metadata
- Authors
- Lim, N. C., Freake, H. C., & Brückner, C.
- Venue
- Chemistry – A European Journal
- Publisher
- Wiley
- Published
- 2004-12-15
- Volume
- 11
- Issue
- 1
- Pages
- 38-49
- ISSN
- 0947-6539 (ISSN-L)
- 1521-3765
- OpenAlex
- W2081054876
- Cited by
- 311
- References
- 1
- FWCI
- 5.49
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lim, N. C., Freake, H. C., & Brückner, C. (2005). Illuminating Zinc in Biological Systems. Chemistry – A European Journal. https://doi.org/10.1002/chem.200400599
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
