The differential diagnosis on the electrocardiogram between ventricular tachycardia and preexcited tachycardia
Open accessAbstract
The 12-lead surface electrocardiogram is a simple and useful tool for the differential diagnosis of regular wide QRS complex tachycardia. However, criteria do not as yet exist to discriminate between ventricular tachycardia and supraventricular tachycardia with anterograde conduction over an accessory pathway (preexcited tachycardia). Therefore, we designed a new stepwise approach with three criteria for the electrocardiographic differential diagnosis between ventricular tachycardia and preexcited tachycardia and prospectively studied 267 regular tachycardias with electrophysiologically proven mechanism and a wide QRS complex (> or = 0.12 s): 149 consecutive ventricular tachycardias and 118 consecutive preexcited regular tachycardias. Underlying heart disease was old myocardial infarction in 133 of 149 (89%) ventricular tachycardias. The patients presenting with preexcited tachycardia had no additional structural heart disease. Atrial fibrillation with preexcited QRS complex was not included. The criteria favoring ventricular tachycardia were: (1) presence of predominantly negative QRS complexes in the precordial leads V4 to V6, (2) presence of a QR complex in one or more of the precordial leads V2 to V6, and (3) AV relation different from 1:1 (more QRS complexes than P waves). The final sensitivity and specificity of these three consecutive steps to diagnose ventricular tachycardia were 0.75 and 1.00, respectively. This new stepwise approach is sensitive and highly specific for the differential diagnosis between ventricular tachycardia in coronary artery disease and preexcited regular tachycardia.
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This algorithm has not been validated in other studies.
“but this algorithm has not been validated in other studies.”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [63]
There has been one report on the analysis of 267 wide-QRS tachycardias, consisting of VT and antidromic AVRT; the derived criteria were found to offer sensitivity of 75% and specificity of 100%.
“There has been one report on the analysis of 267 wide-QRS tachycardias, consisting of VT and antidromic AVRT.The derived criteria were found to offer sensitivity of 75% and specificity of 100%, 63”
From European Heart Rhythm Association (EHRA) consensus document on the management of supraventricular arrhythmias, endorsed by Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), and Sociedad Latinoamericana de Estimulacion Cardiaca y Electrofisiologia (SOLAECE) (2017) · cites this paper as [63]
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Cites
A new approach to the differential diagnosis of a regular tachycardia with a wide QRS complex
Brugada, P., Brugada, J., Mont, L., Smeets, J., & Andries, E. W. (1991) · Circulation · doi:10.1161/01.cir.83.5.1649 · Cited by 738 · see citing works
Wellens, H. J. J., Bär, F. W. H. M., & Lie, K. I. (1978) · The American Journal of Medicine · doi:10.1016/0002-9343(78)90176-6 · Cited by 538 · see citing works
Kindwall, K. E., Brown, J., & Josephson, M. E. (1988) · The American Journal of Cardiology · doi:10.1016/0002-9149(88)91169-1 · Cited by 253 · see citing works
The Differential Morphology of Anomalous Ventricular Complexes of RBBB-Type in Lead V 1
SANDLER, I. A., & MARRIOTR, H. J. L. (1965) · Circulation · doi:10.1161/01.cir.31.4.551 · Cited by 143 · see citing works
Wellens, H. J. J., Bär, F. W. H. M., Vanagt, E. J., Brugada, P., & Farré, J. (1981) · Springer eBooks · doi:10.1007/978-94-009-8239-0_11 · Cited by 75 · see citing works
Spears, B. (1988) · Annals of Emergency Medicine · doi:10.1016/s0196-0644(88)80371-8 · Cited by 20 · see citing works
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Cited by
Sorted by citations
Brugada, J., Katritsis, D. G., Arbelo, E., Arribas, F., Bax, J. J., Blomström‐Lundqvist, C., Calkins, H. G., Corrado, D., Deftereos, S. G., Diller, G., et al. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehz467 · Cited by 1,278 · see citing works
Katritsis, D. G., Boriani, G., Cosio, F. G., Hindricks, G., Jaïs, P., Josephson, M. E., Keegan, R., Kim, Y.-H., Knight, B. P., Kuck, K.-H., et al. (2017) · Europace · doi:10.1093/europace/euw301 · Cited by 188 · see citing works
Diagnostic criteria of broad QRS complex tachycardia: decades of evolution
Alzand, B. S. N., & Crijns, H. J. G. M. (2011) · Europace · doi:10.1093/europace/euq430 · Cited by 93 · see citing works
Jastrzębski, M., Sasaki, K., Kukla, P., Fijorek, K., Stec, S. M., & Czarnecka, D. (2015) · EP Europace · doi:10.1093/europace/euv118 · Cited by 74 · see citing works
“Brugada and aVR algorithms) that rely either on second line algorithms—designed for differentiation between VT and pre-excited tachycardias,(21) or on categorizing misdiagnosis (pre-excited SVT diagnosed to be VT) as a correct diagnosis.(22) Determining the VT score is simple as most of the criteria are well known, an…”
Failure to Agree on the Electrocardiographic Diagnosis of Ventricular Tachycardia
Herbert, M., Votey, S. R., Morgan, M. T., Cameron, P. A., & Dziukas, L. (1996) · Annals of Emergency Medicine · doi:10.1016/s0196-0644(96)70293-7 · Cited by 48 · see citing works
Wide QRS complex tachycardia: ECG differential diagnosis
Brady, W. J., & Skiles, J. (1999) · The American Journal of Emergency Medicine · doi:10.1016/s0735-6757(99)90091-8 · Cited by 45 · see citing works
Jastrzębski, M., Moskal, P., Kukla, P., Fijorek, K., Kisiel, R., & Czarnecka, D. (2017) · Annals of Noninvasive Electrocardiology · doi:10.1111/anec.12493 · Cited by 22 · see citing works
“Steurer algorithm criteria (predominantly negative QRS complexes from V4 to V6, qR complex in any of V2–V6, AV dissociation) (Steurer et al., 1994).”
BackgroundMethodInfluentialSchleifer, J. W., & Srivathsan, K. S. (2013) · Cardiology Clinics · doi:10.1016/j.ccl.2013.07.007 · Cited by 22 · see citing works
Differential Diagnosis of Wide QRS Tachycardias
Katritsis, D. G., & Brugada, J. (2020) · Arrhythmia & Electrophysiology Review · doi:10.15420/aer.2020.20 · Cited by 19 · see citing works
“The criteria derived from this analysis were found to have a sensitivity of 75% and specificity of 100% and the algorithm was validated in another study but experience is still limited.(18,19)”
MethodElectrocardiographic manifestations: ventricular tachycardia
Hudson, K. B., Brady, W. J., Chan, T. C., Pollack, M. L., & Harrigan, R. A. (2003) · Journal of Emergency Medicine · doi:10.1016/s0736-4679(03)00207-5 · Cited by 19 · see citing works
Ventricular Tachycardias with Left Bundle Branch Block Morphology
Nibley, C., & Wharton, J. M. (1995) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.1995.tb02524.x · Cited by 19 · see citing works
Samesima, N., God, E. M. G., Kruse, J. C. L., Leal, M. G., Pinho, C., França, F. F., Pimenta, J., Cardoso, A. F., Paixão, A., da Fonseca, A. J., et al. (2022) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20220623 · Cited by 18 · see citing works
Pastore, C. A., Pinho, C., Germiniani, H., Samesima, N., & Mano, R. (2009) · Arquivos Brasileiros de Cardiologia · doi:10.1590/s0066-782x2009001800001 · Cited by 15 · see citing works
Management of Arrhythmias in the Emergency Department
HOOD, R. E., & Shorofsky, S. R. (2006) · Cardiology Clinics · doi:10.1016/j.ccl.2005.09.005 · Cited by 12 · see citing works
“Other morphologic features that suggest VT include a QRS width greater than 160 milliseconds, the QRS axis in the frontal plane (far left or right), concordance of the QRS complexes across the precordium, and a time from the onset of the R wave to the nadir of the S wave in any precordial lead of more than 100 millise…”
BackgroundVereckei, A., Simon, A., Szénási, G., & Miller, J. M. (2023) · Heart Lung and Circulation · doi:10.1016/j.hlc.2023.03.016 · Cited by 11 · see citing works
Bedside Diagnosis of Wide QRS Tachycardia
Barold, S. S. (1995) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.1995.tb04634.x · Cited by 8 · see citing works
Management of Cardiac Arrhythmias
Reynolds, E. W., & Johnston, F. D. (2007) · Humana Press eBooks · doi:10.1007/978-1-59745-238-0_14 · Cited by 8 · see citing works
Медведев, М. М. (2020) · Journal of Arrhythmology · doi:10.35336/va-2019-3-48-56 · Cited by 7 · see citing works
“Практически во всех обсуждаемых исследованиях в группе СВТ превалировали более молодые пациенты с отсутствием кардиальной патологии, тогда как в группе ЖТ большинство больных имели структурную патологию сердца, в том числе и очаговые рубцовые изменения, обусловленные ранее перенесенным ОИМ [13, 18, 23-25].”
Part 6: Advanced Cardiovascular Life Support
arrhythmias., P. A. T. A. L. S. B. A. T. R. T. F. (2000) · Circulation · doi:10.1161/circ.102.suppl_1.i-112 · Cited by 6 · see citing works
Ni, H., Wang, Q., Wang, Z., Xu, W., Pan, X., Zhu, J., Liu, Z., & Cai, W. (2024) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2024.153817 · Cited by 4 · see citing works
Supraventricular arrhythmia: electrocardiographic aspects
de Luna, A. B. (2016) · Medwave · doi:10.5867/medwave.2016.6815 · Cited by 4 · see citing works
Wide QRS tachycardias: the rationale behind electrocardiographic diagnostic criteria
Marinucci, L. F. B., & Chalela, W. A. (2020) · Journal of Cardiac Arrhythmias · doi:10.24207/jca.v33i3.3408 · Cited by 3 · see citing works
Budanova, M. A., Chmelevsky, M. P., Treshkur, T. V., & Тихоненко, В. М. (2021) · Journal of Arrhythmology · doi:10.35336/va-2020-4-24-32 · Cited by 3 · see citing works
Electrocardiographic Differential Diagnosis of Narrow QRS and Wide QRS Complex Tachycardias
Song, B. G. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.102568 · Cited by 3 · see citing works
Discrimination between ventricular tachycardia and wide‐QRS preexcited tachycardia
Lee, J. H. (2024) · Annals of Noninvasive Electrocardiology · doi:10.1111/anec.13112 · Cited by 3 · see citing works
“three studies compared only specificity and did not included con-trol group (Jastrzębski et al., 2018), while the others by Steurer and Verechei, reported sensitivity and specificity (75% and 100%; 73% and 74.6%), respectively (Steurer et al., 1994; Vereckei et al., 2023).”
BackgroundInfluentialRhythm and Conduction Disturbances in Stress Testing
Thomas, G. S., & Balouch, M. (2018) · doi:10.1093/med/9780190225483.003.0010 · Cited by 3 · see citing works
Part 6: Advanced Cardiovascular Life Support
(2000) · Resuscitation · doi:10.1016/s0300-9572(00)00278-1 · Cited by 3 · see citing works
Torsade de Pointes, Ventricular Fibrillation, and Differential Diagnosis of Wide QRS Tachycardias
(2008) · Elsevier eBooks · doi:10.1016/b978-141603774-3.10018-8 · Cited by 2 · see citing works
Diagnóstico diferencial de las taquicardias de complejo ancho: un desafío permanente
René Asenjo, G., Morris, R., Sanhueza, E. J., Ortiz, M. A., & Cereceda, M. (2020) · Revista chilena de cardiología · doi:10.4067/s0718-85602020000100055 · Cited by 2 · see citing works
Clinical Use of Electrocardiogram
Lakshmanadoss, U. (2022) · IntechOpen eBooks · doi:10.5772/intechopen.98009 · Cited by 1 · see citing works
Ni, H., Huang, Y., Pan, X., Zhang, X., Wan, Z., Zhai, C., & Pan, H. (2025) · BMC Cardiovascular Disorders · doi:10.1186/s12872-025-04583-1 · Cited by 1 · see citing works
“(2)Algorithm to differentiate VT from PXT (Brugada Three-Step Algorithm [4]), analyze step by step according to ⑤ ~ ⑦ , if it meets the criteria, it is diagnosed as VT, otherwise it is diagnosed as PXT. ⑤ QRS complex in leads V4~V6 is mainly negative wave.”
Ablation of Posteroseptal Accessory Pathways
Daubert, J. P., & Sze, E. Y. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-52992-1.00024-7 · Cited by 1 · see citing works
Gazmuri, R. J., & Santonocito, C. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-1367-1.00079-3 · Cited by 1 · see citing works
Active Ventricular Arrhythmias
de Luna, A. B. (2012) · doi:10.1002/9781118392041.ch16 · Cited by 1 · see citing works
The Differential Diagnosis of Wide Complex Tachycardia—ED Diagnostic and Management Considerations
Charlton, N. P., & Brady, W. J. (2011) · doi:10.1002/9781119959809.ch8 · Cited by 1 · see citing works
The Presence of a Q Wave in Lead V5 Excludes Manifest Preexcitation
Pavri, B. B., Coyne, R. F., & Kocovic, D. Z. (1999) · Annals of Noninvasive Electrocardiology · doi:10.1111/j.1542-474x.1999.tb00060.x
Supraventricular or ventricular tachycardia?
Lambiase, P. D. (2005) · British Journal of Hospital Medicine · doi:10.12968/hmed.2005.66.sup2.19716
Mark, D. G., Brady, W. J., & Pines, J. M. (2010) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2009.11.003
Diagnostik og behandling af paroksystisk supraventrikulær takykardi
Rujic, D., Sundbøll, J., Tofig, B. J., Nielsen, J. C., & Pareek, M. (2016) · Ugeskrift for Læger
Perez, A., Alberto, C., & Grupi, C. (2009)
Gianni, C., Chen, Q., Canpolat, U., Rocca, D. G. D., Al‐Ahmad, A., Burkhardt, J. D., & Natale, A. (2020) · Contemporary cardiology · doi:10.1007/978-3-030-41967-7_8
Differential diagnosis of wide-QRS (>120 ms) tachycardias
Katritsis, D. G., & Morady, F. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-79338-4.00020-0
Active Ventricular Arrhythmias
Bayés‐Genís, A., Fiol, M., Bayés‐Genís, A., Baranchuk, A. M., Elosúa, R., & Martínez‐Sellés, M. (2021) · doi:10.1002/9781119536475.ch16
Active Ventricular Arrhythmias
de Luna, A. B. (2011) · doi:10.1002/9781444391749.ch5
Active Ventricular Arrhythmias
de Luna, A. B., & FCCS, A. B. M. F. F. (2017) · doi:10.1002/9781119212782.ch5
KHAN, M. G. (2014) · Contemporary cardiology · doi:10.1007/978-1-61779-962-4_14
de Luna, A. B. (2014) · doi:10.1002/9781118821350.biblio
Wide QRS complex tachycardia: the underlying mechanisms, differential diagnosis and acute treatment
Solovyan, А. M., & Mikhalieva, Т. V. (2022) · Medicine of Ukraine · doi:10.37987/1997-9894.2022.8(264).271836
Bouar, R. L., Halbwachs, F., Robein, T., Daval, C., Schiau, S., Calcaianu, M., Thinot, B., & Lévy, J. (2023) · Springer eBooks · doi:10.1007/978-3-031-35579-0_17
Wide QRS complex tachycardia: differential diagnosis and acute treatment
Sychov, O. S., Solovyan, А. M., Mikhalieva, Т. V., Androsova, L. O., & Lyzogub, S. V. (2023) · Medicine of Ukraine · doi:10.37987/1997-9894.2023.8(274).294172
Ni, H., Huang, Y., Pan, X., Zhang, X., Xu, L., Wang, Z., Zhai, C., & Pan, H. (2025) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2025.153937
Park, S.-J., Lee, H. J., Kim, J., & Park, K. (2025) · JACC Case Reports · doi:10.1016/j.jaccas.2025.106295
Wide QRS complex tachycardias: Are you bothered by irregularity?
Miller, J. M., Vasilottos, N., & Vanka, V. (2026) · Indian Pacing and Electrophysiology Journal · doi:10.1016/j.ipej.2026.07.014
“Steurer et al. [2] studied 149 VTs and 117 PXTs using 3 criteria (predominant negative QRS in V 4 -”
- Authors
- Steurer, G., Gürsoy, S., Frey, B., Simonis, F., Andries, E., Brugada, P., & Kuck, K.
- Affiliations
- Onze Lieve Vrouwziekenhuis Hospital (BE)
- Corresponding author
- Brugada, Pedro
- Venue
- Clinical Cardiology
- Publisher
- Wiley
- Published
- 1994-06
- Volume
- 17
- Issue
- 6
- Pages
- 306-308
- ISSN
- 0160-9289 (ISSN-L)
- 1932-8737
- OpenAlex
- W1980106498
- Cited by
- 53
- References
- 6
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 3 · 2022: 4 · 2021: 3 · 2020: 5 · 2019: 2 · 2018: 1 · 2017: 2 · 2016: 3 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 1
- FWCI
- 0.95
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinical Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Austrian Science Fund
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Keywords
- ventricular tachycardia, wide QRS tachycardia, accessory pathway, coronary artery disease, myocardial infarction
- MeSH terms
- Coronary Disease, Diagnosis, Differential, Electrocardiography, Humans, Pre-Excitation Syndromes, Prospective Studies, Sensitivity and Specificity, Tachycardia, Ventricular
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