The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Co‐Delivery of Hydrophobic and Hydrophilic Drugs from Nanoparticle–Aptamer Bioconjugates
Abstract
Herein we report a novel targeted drug delivery system consisting of nanoparticle–aptamer bioconjugates, which can carry both hydrophobic and hydrophilic chemotherapeutic drugs simultaneously, and deliver them selectively in a targeted and temporally distinct manner. This work provides a robust platform for targeted co-delivery of chemotherapeutic agents with the hope of both leveraging the synergistic effects of multiple drugs and also potentially suppressing the likelihood of drug resistance by the treated tissues.
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Cites
Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology
Peppas, N. A., Hilt, J. Z., Khademhosseini, A., & Langer, R. (2006) · Advanced Materials · doi:10.1002/adma.200501612 · Cited by 4,109
Self-citationFormulation of functionalized PLGA-PEG Nanoparticles for in vivo targeted drug delivery
Cheng, J., Teply, B. A., Sherifi, I., Sung, J., Luther, G., Gu, F. X., Levy-Nissenbaum, E., Radovic-Moreno, A. F., Langer, R., & Farokhzad, O. C. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2006.09.047 · Cited by 1,273
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Cited by
Nanoparticles in Medicine: Therapeutic Applications and Developments
Zhang, L., Gu, F., Chan, J., Wang, A., Langer, R., & Farokhzad, O. (2008) · Clinical Pharmacology & Therapeutics · doi:10.1038/sj.clpt.6100400 · Cited by 2,657
Self-citationNanotechnology in Drug Delivery and Tissue Engineering: From Discovery to Applications
Shi, J., Votruba, A. R., Farokhzad, O. C., & Langer, R. (2010) · Nano Letters · doi:10.1021/nl102184c · Cited by 1,612
Self-citationNanoparticle-based combination therapy toward overcoming drug resistance in cancer
Hu, C.-M. J., & Zhang, L. (2012) · Biochemical Pharmacology · doi:10.1016/j.bcp.2012.01.008 · Cited by 686
Self-citationRecent advances of cocktail chemotherapy by combination drug delivery systems
Hu, Q., Sun, W., Wang, C., & Gu, Z. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.10.022 · Cited by 625
Nanoparticle Technologies for Cancer Therapy
Alexis, F., Pridgen, E. M., Langer, R., & Farokhzad, O. C. (2010) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-642-00477-3_2 · Cited by 364
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Metadata
- Authors
- Zhang, L., Radovic‐Moreno, A. F., Alexis, F., Gu, F. X., Basto, P. A., Bagalkot, V., Jon, S., Langer, R. S., & Farokhzad, O. C.
- Venue
- ChemMedChem
- Publisher
- Wiley
- Published
- 2007-08-31
- Volume
- 2
- Issue
- 9
- Pages
- 1268-1271
- ISSN
- 1860-7179 (ISSN-L)
- 1860-7187
- OpenAlex
- W2035264169
- Cited by
- 257
- References
- 2
- FWCI
- 5.62
- Type
- journal article
- Language
- en
- Open access
- closed
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