The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
Influence of body mass index on outcomes and treatment‐related toxicity in patients with colon carcinoma
Abstract
BACKGROUND: Obesity is a risk factor for the development of colon carcinoma. The influence of body mass index (BMI) on long‐term outcomes and treatment‐related toxicity in patients with colon carcinoma has not been well characterized. METHODS: This cohort study was conducted within a large, randomized adjuvant chemotherapy trial of 3759 men and women with high‐risk, Stage II and Stage III colon carcinoma who were treated between 1988 and 1992 throughout the United States. With a median follow‐up of 9.4 years, the authors examined the influence of BMI on disease recurrence, overall survival, and treatment‐related toxicity. RESULTS: Compared with women of normal weight (BMI, 21.0–24.9 kg/m 2), obese women with colon carcinoma (BMI ≥ 30.0 kg/m 2) experienced significantly worse overall mortality (hazard ratio [HR], 1.34; 95% confidence interval [95% CI], 1.07–1.67) and a nonsignificant increase in the risk of disease recurrence (HR, 1.24; 95% CI, 0.98–1.59). The influence of BMI among women was not related to any differences in chemotherapy dose‐intensity across categories of BMI. In contrast, BMI was not related significantly to long‐term outcomes among male patients in this cohort. Among all study participants, obese patients had significantly lower rates of Grade 3–4 leukopenia and lower rates of any Grade ≥ 3 toxicity compared with patients of normal weight. CONCLUSIONS: Among women with Stage II–III colon carcinoma, obesity was associated with a significant increase in overall mortality as well as a borderline significant increase in disease recurrence. Nonetheless, obesity was not associated with any increase in chemotherapy‐related toxicity. Cancer 2003;98:484–95. © 2003 American Cancer Society. DOI 10.1002/cncr.11544
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Nonparametric Estimation from Incomplete Observations
Kaplan, E. L., & Meier, P. (1992) · Springer Series in Statistics · doi:10.1007/978-1-4612-4380-9_25 · Cited by 45,181
Regression Models and Life-Tables
Cox, D. R. (1972) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1972.tb00899.x · Cited by 39,793
Regression Models and Life-Tables
Cox, D. R. (1992) · Springer Series in Statistics · doi:10.1007/978-1-4612-4380-9_37 · Cited by 26,297
Simplified calculation of body surface area
(1987) · New England Journal of Medicine · doi:10.1056/nejm198710223171717 · Cited by 3,238
Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome
Wajchenberg, B. L. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.6.0415 · Cited by 2,961
Spiess, P. E., Lee, A. K., Leibovici, D., Wang, X., Do, K., & Pisters, L. L. (2006) · Cancer · doi:10.1002/cncr.21979 · Cited by 1,930
Relation of Body Fat Distribution to Metabolic Complications of Obesity*
KISSEBAH, A. H., VYDELINGUM, N., MURRAY, R., EVANS, D. J., KALKHOFF, R. K., & ADAMS, P. W. (1982) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-54-2-254 · Cited by 1,909
Krotkiewski, M., Björntorp, P., Sjöström, L., & Smith, U. (1983) · Journal of Clinical Investigation · doi:10.1172/jci111040 · Cited by 1,456
Role of the Insulin-Like Growth Factor Family in Cancer Development and Progression
Yu, H. (2000) · Journal of the National Cancer Institute · doi:10.1093/jnci/92.18.1472 · Cited by 1,424
Ma, J., Pollak, M. N., Giovannucci, E., Chan, J. M., Tao, Y., Hennekens, C. H., & Stampfer, M. J. (1999) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/91.7.620 · Cited by 1,119
Cited by
Nutrition and physical activity guidelines for cancer survivors
Rock, C. L., Doyle, C., Demark‐Wahnefried, W., Meyerhardt, J., Courneya, K. S., Schwartz, A. L., Bandera, E. V., Hamilton, K. K., Grant, B., McCullough, M., et al. (2012) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21142 · Cited by 1,995
Self-citationWolin, K. Y., Carson, K., & Colditz, G. A. (2010) · The Oncologist · doi:10.1634/theoncologist.2009-0285 · Cited by 778
Petrelli, F., Cortellini, A., Indini, A., Tomasello, G., Ghidini, M., Nigro, O., Salati, M., Dottorini, L., Iaculli, A., Varricchio, A., et al. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.3520 · Cited by 530
Ogino, S., Chan, A. T., Fuchs, C. S., & Giovannucci, E. (2011) · Gut · doi:10.1136/gut.2010.217182 · Cited by 522
Self-citationGriggs, J. J., Mangu, P. B., Anderson, H., Balaban, E. P., Dignam, J. J., Hryniuk, W. M., Morrison, V. A., Pini, T. M., Runowicz, C. D., Rosner, G. L., et al. (2012) · Journal of Clinical Oncology · doi:10.1200/jco.2011.39.9436 · Cited by 485
Metadata
- Authors
- Meyerhardt, J. A., Catalano, P. J., Haller, D. G., Mayer, R. J., Benson, A. B., Macdonald, J. S., & Fuchs, C. S.
- Venue
- Cancer
- Publisher
- Wiley
- Published
- 2003-06-30
- Volume
- 98
- Issue
- 3
- Pages
- 484-495
- ISSN
- 0008-543X (ISSN-L)
- 1097-0142
- OpenAlex
- W2076573488
- Cited by
- 306
- References
- 65
- FWCI
- 4.15
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Influence of body mass index on outcomes and treatment‐related toxicity in patients with colon carcinoma. https://app.cochat.ai/papers/10.1002/cncr.11544
- The paper
- Meyerhardt, J. A., Catalano, P. J., Haller, D. G., Mayer, R. J., Benson, A. B., Macdonald, J. S., & Fuchs, C. S. (2003). Influence of body mass index on outcomes and treatment‐related toxicity in patients with colon carcinoma. Cancer. https://doi.org/10.1002/cncr.11544
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
