L‐asparaginase treatment in acute lymphoblastic leukemia: A focus on Erwinia asparaginase

Summary of product characteristics

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L-asparaginase: a review of microbial production and protein engineering with translational applications for oncology and food safety

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Role of Enzymes in Pharmaceutical and Biotechnology Industries

Singu, B. D., & Annapure, U. S. (2018) · Springer eBooks · doi:10.1007/978-981-13-1933-4_9 · Cited by 7

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Protein re-surfacing of E. coli L-Asparaginase to evade pre-existing anti-drug antibodies and hypersensitivity responses

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A Toolbox for Glutamine Use in Dissolution Dynamic Nuclear Polarization: from Enzymatic Reaction Monitoring to the Study of Cellular Metabolic Pathways and Imaging

dos Santos, K. C., Bertho, G., Caradeuc, C., Baud, V., Montagne, A., Abergel, D., Giraud, N., & Baudin, M. (2023) · ChemPhysChem · doi:10.1002/cphc.202300151 · Cited by 7

Interaction between Gallic acid and Asparaginase to potentiate anti-proliferative effect on lymphoblastic leukemia cell line

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A method for measurement of human asparagine synthetase (ASNS) activity and application to ASNS protein variants associated with ASNS deficiency

Chang, M. C., Staklinski, S. J., Merritt, M. E., & Kilberg, M. S. (2023) · Biology Methods and Protocols · doi:10.1093/biomethods/bpad026 · Cited by 6

Engineering Tk1656, a highly active l-asparaginase from Thermococcus kodakarensis, for enhanced activity and stability

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Measurement of Subvisible Particulates in Lyophilised Erwinia chrysanthemi l-asparaginase and Relationship with Clinical Experience

Gervais, D. P., Corn, T., Downer, A., Smith, S. W., & Jennings, A. (2014) · The AAPS Journal · doi:10.1208/s12248-014-9612-9 · Cited by 6

Production, Purification and Standardization of Anticancerous Enzyme (L-Asparaginases) from Aspergillus Niger Using Soil Samples by Solid State Fermentation

Rahiman, O. M. F., Mohthash, M., Faris, U. S., Muneersha, T. K. M., & Shejina, M. (2014) · International Journal of Applied Sciences and Biotechnology · doi:10.3126/ijasbt.v2i4.11278 · Cited by 6

Design, synthesis and application of fluorogenic probe for detecting l-asparaginase in serum samples

Wang, L., Qin, W., Chen, D., Wang, N., Zhang, C., Fang, Z., Fang, B., Du, W., Yang, N., Wu, Q., et al. (2021) · Results in Chemistry · doi:10.1016/j.rechem.2021.100103 · Cited by 6

L-asparaginase: New about Well-Known Drug

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l-Asparaginases from hyperthermophilic archaea and their applications

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L-asparaginase-mediated Therapy in L-asparagine Auxotrophic Cancers: A Review

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Isolation and identification of marine Bacillus altitudinis KB1 from coastal Kerala: asparaginase producer

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Mechanism and application of nonessential amino acid deprivation associated with tumor therapy

Nong, S., Qian, Y., Zhang, T., Zhou, X., Wei, Y., Yin, X., & Ma, X. (2022) · MedComm – Future Medicine · doi:10.1002/mef2.12 · Cited by 6

Hypersensitivity Reactions to Native E. coli L-asparaginase in Children With Acute Lymphoblastic Leukemia Treated in Trial ALL-BFM 2000: Impact of Treatment Schedule and Type of Glucocorticoid in Induction

Möricke, A., Rizzari, C., Alten, J., Attarbaschi, A., Beier, R., Biondi, A., Burkhardt, B., Bodmer, N., Boos, J., Cario, G., et al. (2023) · HemaSphere · doi:10.1097/hs9.0000000000000888 · Cited by 6

Actualización del tratamiento con L-asparraginasa en Pediatría

Guilleme, C. M., Delgado, R. F., Sevilla, J., Astigarraga, I., Rives, S., Codina, J. S. D. T., Soler, J. L. F., Ramirez, L. P., Garicano, J. M., Martínez, B. G., et al. (2013) · Anales de Pediatría · doi:10.1016/j.anpedi.2013.03.015 · Cited by 6

The role of the quaternary structure in the activation of human L-asparaginase

de Morais, S. B., Pirolla, R. A. S., Frota, N. T. S., Lourenzoni, M. R., Gozzo, F. C., & Souza, T. A. C. B. (2020) · Journal of Proteomics · doi:10.1016/j.jprot.2020.103818 · Cited by 6

Chemotherapy Drug Shortages in Pediatric Oncology: A Global Public Health Crisis Threatening Our Children

Pommert, L., & Tasian, S. K. (2021) · The Hematologist · doi:10.1182/hem.v18.4.2021412 · Cited by 6

Chimeric spider silk production in microalgae: a modular bionanomaterial

Molino, J. V. D., Lubiana, T., Ferreira‐Camargo, L. S., Croce, M., Tanaka, A., Buson, F. X., Ribeiro, P., Campos-Salazar, A., Antonio, E., Maizel, A., et al. (2016) · Research Ideas and Outcomes · doi:10.3897/rio.2.e9342 · Cited by 6

Expression and purification of L-asparaginase fromEscherichia coliand the inhibitory effects of cyclic dipeptides

Zhang, Y., Li, D., & Li, Y. (2017) · Natural Product Research · doi:10.1080/14786419.2016.1277350 · Cited by 6

Plasma asparaginase activity, asparagine concentration, and toxicity after administration of Erwinia asparaginase in children and young adults with acute lymphoblastic leukemia: Phase I/II clinical trial in Japan

Ogawa, C., Taguchi, F., Goto, H., Koh, K., Tomizawa, D., Ohara, A., & Manabe, A. (2017) · Pediatric Blood & Cancer · doi:10.1002/pbc.26475 · Cited by 6

Biologics, Biosimilars, and Biobetters: Therapeutic Innovations Reshaping Modern Medicine

Pascual, J. C. K. S., & Kangsamaksin, T. (2025) · Advanced Biology · doi:10.1002/adbi.202500326 · Cited by 5

Cinchonain Ia Shows Promising Antitumor Effects in Combination with L-Asparaginase-Loaded Nanoliposomes

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Predictive factors for l-asparaginase hypersensitivity in pediatric acute lymphoblastic leukemia

Choed-Amphai, C., Khorana, J., Sathitsamitphong, L., Natesirinilkul, R., & Charoenkwan, P. (2024) · International Journal of Hematology · doi:10.1007/s12185-024-03725-z · Cited by 5

Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1

Nag, N. K., Ray, T., Tapader, R., Gope, A., Das, R., Mahapatra, E., Saha, S., Pal, A., Prasad, P., & Pal, A. (2024) · iScience · doi:10.1016/j.isci.2024.109828 · Cited by 5

Higher plasma asparaginase activity after intramuscular than intravenous Erwinia asparaginase

Panetta, J. C., Liu, Y., Swanson, H. D., Karol, S. E., Pui, C., Inaba, H., Jeha, S., & Relling, M. V. (2020) · Pediatric Blood & Cancer · doi:10.1002/pbc.28244 · Cited by 5

L-asparaginase in the treatment of patients with acute lymphoblastic leukemia

Egler, R. A., Ahuja, S. P., & Matloub, Y. (2016) · Journal of Pharmacology and Pharmacotherapeutics · doi:10.4103/0976-500x.184769 · Cited by 334

Asparaginase therapy in patients with acute lymphoblastic leukemia: expert opinion on use and toxicity management

Sandley, M., & Angus, J. (2023) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428194.2023.2171267 · Cited by 13

Optimizing asparaginase therapy for acute lymphoblastic leukemia

Rizzari, C., Conter, V., Starý, J., Colombini, A., Moericke, A., & Schrappe, M. (2013) · Current Opinion in Oncology · doi:10.1097/cco.0b013e32835d7d85 · Cited by 93

Asparaginase Erwinia chrysanthemi as a component of a multi-agent chemotherapeutic regimen for the treatment of patients with acute lymphoblastic leukemia who have developed hypersensitivity to E. coli-derived asparaginase

Figueiredo, L. M., Cole, P. D., & Drachtman, R. A. (2016) · Expert Review of Hematology · doi:10.1586/17474086.2016.1142370 · Cited by 23

Erwinia asparaginase in pediatric acute lymphoblastic leukemia

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