Tau isoform regulation is region‐ and cell‐specific in mouse brain

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Items 101–186 of 186

1. Pathogenic Tau Protein Species: Promising Therapeutic Targets for Ocular Neurodegenerative Diseases
   Mohammad Amir Mishan, Mozhgan Rezaei Kanavi, Koorosh Shahpasand, Hamid Ahmadieh · 2019 · Journal of Ophthalmic and Vision Research
2. Novel monoclonal antibodies targeting the microtubule-binding domain of human tau
   Cara L. Croft, Brenda D. Moore, Yong Ran, Paramita Chakrabarty, Yona Levites, Todd Eliot Golde, Benoit I. Giasson · 2018 · PLoS ONE
3. Developmental Pathogenicity of 4-Repeat Human Tau Is Lost with the P301L Mutation in Genetically Matched Tau-Transgenic Mice
   Julia Gamache, Lisa J. Kemper, Elizabeth L. Steuer, Kailee Leinonen-Wright, Jessica M. Choquette, Chris J.W. Hlynialuk, Kellie A. Benzow, Keith A. Vossel, Weiming Xia, Michael D. Koob et al. · 2019 · Journal of Neuroscience
4. Caspase-6-cleaved Tau fails to induce Tau hyperphosphorylation and aggregation, neurodegeneration, glial inflammation, and cognitive deficits
   Anastasia Noël, Bénédicte Foveau, Andrea Claire LeBlanc · 2021 · Cell Death and Disease
5. A familial Danish dementia rat shows impaired presynaptic and postsynaptic glutamatergic transmission
   Yin, Tao, Yao, Wen, Norris, Kelly A., D’Adamio, Luciano · 2021 · Journal of Biological Chemistry
6. Genetic ablation of tau in postnatal neurons rescues decreased adult hippocampal neurogenesis in a tauopathy model
   Sarah Houben, Karelle Leroy, Kunié Ando, Zehra Yilmaz, Cyprien Widomski, Luc Buée, Jean‐Pierre Brion · 2019 · Neurobiology of Disease
7. Disease-modifying strategies in primary tauopathies
   Thomas W. Rösler, Márcia Costa, Günter U. Höglinger · 2019 · Neuropharmacology
8. Co-Expression of Three Wild-Type 3R-Tau Isoforms Induces Memory Deficit via Oxidation-Related DNA Damage and Cell Death: A Promising Model for Tauopathies
   Cheng Xu, Jing Guo, Li Li, Xin Wang, Qiuzhi Zhou, Dongsheng Sun, Shujuan Zhang, Shihong Li, Jinwang Ye, Yanchao Liu et al. · 2019 · Journal of Alzheimer s Disease
9. Rodent Models for Alzheimer’s Disease in Drug Discovery
   James E. Barrett, Paul McGonigle · 2016 · Elsevier eBooks
10. Capacity for Seeding and Spreading of Argyrophilic Grain Disease in a Wild-Type Murine Model; Comparisons With Primary Age-Related Tauopathy
    Isidró Ferrer, Pol Andrés‐Benito, Julia Sala‐Jarque, Vanessa Gil, José Antonio del Rı́o · 2020 · Frontiers in Molecular Neuroscience
11. Tau Isoform-Driven CBD Pathology Transmission in Oligodendrocytes in Humanized Tau Mice
    Justyna Zarȩba-Pasławska, Kalicharan Patra, Luca Kluzer, Tamás Révész, Per Svenningsson · 2021 · Frontiers in Neurology
12. Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency
    Alysa Kasen, Sofia Lövestam, Elizabeth Breton, Lindsay K. Meyerdirk, Jacob Alec McPhail, Kristin Piché, Ariel Louwrier, Colt D. Capan, Hyoungjoo Lee, Sjors H. W. Scheres et al. · 2025 · Nature Communications
13. Detecting the Undetectable: Advances in Methods for Identifying Small Tau Aggregates in Neurodegenerative Diseases
    Dorothea Böken, Yunzhao Wu, Zi-Wei Zhang, David Klenerman · 2024 · ChemBioChem
14. Excessive Alcohol Use as a Risk Factor for Alzheimer’s Disease: Epidemiological and Preclinical Evidence
    Paige E. Anton, Nicole M. Maphis, David N. Linsenbardt, Leon G. Coleman · 2025 · Advances in experimental medicine and biology
15. Differential Effects of Human Tau Isoforms to Neuronal Dysfunction and Toxicity in the Drosophila CNS
    Ergina Vourkou, Vassilis Paspaliaris, Anna Bourouliti, Maria-Christina Zerva, Engie Prifti, Katerina Papanikolopoulou, Efthimios M. C. Skoulakis · 2022 · International Journal of Molecular Sciences
16. Tau expression and phosphorylation in enteroendocrine cells
    Guillaume Chapelet, Nora Béguin, Blandine Castellano, Isabelle Grit, Pierre de Coppet, Thibauld Oullier, Michel Neunlist, Hervé M. Blottière, Malvyne Rolli‐Derkinderen, Gwenola Le Dréan et al. · 2023 · Frontiers in Neuroscience
17. Validation of Tau Antibodies for Use in Western Blotting and Immunohistochemistry
    Michael J. Ellis, Christiana Lekka, Hanna Tulmin, Darragh Patrick O'Brien, Shalinee Dhayal, Marie‐Louise Zeissler, Jakob Grunnet Knudsen, Benedikt Mathias Kessler, Noel G. Morgan, John A. Todd et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
18. Analysis of early effects of human APOE isoforms on Alzheimer’s disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOE
    Yesiltepe, Metin, Yin, Tao, Tambini, Marc, Bao, Hanmei, Pan, Meixia, d’Abramo, Cristina, Giliberto, Luca, Han, Xianlin, D’Adamio, Luciano · 2024 · Cell Communication and Signaling
19. Deregulated Transcription and Proteostasis in Adult mapt Knockout Mouse
    Pol Andrés‐Benito, África Flores, Sara Busquet-Areny, Margarita Carmona, Karina Ausín, Paz Cartas‐Cejudo, Mercedes Lachén‐Montes, José Antonio del Rı́o, Joaquín Fernández‐Irigoyen, Enrique Santamaría et al. · 2023 · International Journal of Molecular Sciences
20. Twenty years of therapeutic development in tauopathy mouse models: a scoping review
    Vanessa F. Langness, Danielle A. Simmons, Tyne L.M. McHugh, Robert R. Butler, James Zhou, Harry Liu, Tao Yang, Lisa Ellerby, Frank M. Longo · 2025 · Alzheimer s & Dementia
21. Targeting Microtubule-Associated Protein Tau in Chemotherapy-Resistant Models of High-Grade Serous Ovarian Carcinoma
    Maria V. Barbolina · 2022 · Cancers
22. Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts
    Badri Narayan Vardarajan, David Vergote, Fadel Tissir, Mark W. Logue, Jing Yang, Nathalie Daude, Kunié Ando, Ekaterina A. Rogaeva, Joseph Jonathan Lee, Rong Cheng et al. · 2013 · Molecular Neurodegeneration
23. Transcriptomic Changes in Brain Development
    Allissa Dillman, Mark Cookson · 2014 · International review of neurobiology
24. Genotype-Specific Differences between Mouse CNS Stem Cell Lines Expressing Frontotemporal Dementia Mutant or Wild Type Human Tau
    Miranda E. Orr, Rose Pitstick, Brenda Canine, Karen H. Ashe, George A. Carlson · 2012 · PLoS ONE
25. Expression of 1N3R-Tau Isoform Inhibits Cell Proliferation by Inducing S Phase Arrest in N2a Cells
    Li Li, Zhipeng Xu, Gong‐Ping Liu, Cheng Xu, Zhi-Hao Wang, Xiaoguang Li, En-Jie Liu, Juan Zeng, Damin Chai, Wenlong Yao et al. · 2015 · PLoS ONE
26. Tau modulates visual plasticity in adult and old mice
    Léa Rodriguez, Sandrine Joly, Fayçal Zine-Eddine, Julius Baya Mdzomba, Vincent Pernet · 2020 · Neurobiology of Aging
27. Limitations and Applications of Rodent Models in Tauopathy and Synucleinopathy Research
    Emma Szegvari, Sara A. M. Holec, Amanda L. Woerman · 2025 · Journal of Neurochemistry
28. Expression of tau and phosphorylated tau in the brain of normal and hemiparkinsonian rhesus macaques
    Julia C. Gambardella, Wyatt Schoephoerster, Viktoriya Bondarenko, Brian S. Yandell, Marina Elena Emborg · 2023 · The Journal of Comparative Neurology
29. Polymeric alkylpyridinium salts permit intracellular delivery of human Tau in rat hippocampal neurons: requirement of Tau phosphorylation for functional deficits
    David J. Koss, Lianne Robinson, Anna Mietelska‐Porowska, Anna Gąsiorowska, Kristina Sepčić, Tom Turk, Marcel Jaspars, Grażyna Niewiadomska, Roderick H. Scott, Bettina Platt et al. · 2015 · Cellular and Molecular Life Sciences
30. A model of traumatic brain injury using human iPSC-derived cortical brain organoids
    Jesse D. Lai, Joshua E. Berlind, Gabriella Fricklas, Naomi S. Sta Maria, Russell E. Jacobs, Violeta L. Yu, Justin K. Ichida · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
31. Transfixed by transgenics: how pathology assumptions are slowing progress in Alzheimer's disease and related dementia research
    Luciano D'adamio · 2023 · EMBO Molecular Medicine
32. CELF2 promotes tau exon 10 inclusion via hinge domain-mediated nuclear condensation
    Xin Li, Ishana N. Syed, Zhao Zhang, Rashmi Adhikari, Dan Tang, Su Hyuk Ko, Zhijie Liu, Lizhen Chen · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
33. Initial assessment of the spatial learning, reversal, and sequencing task capabilities of knock-in rats with humanizing mutations in the Aβ-coding region of App
    Pham, Hoa, Yin, Tao, D’Adamio, Luciano · 2022 · PLOS ONE
34. Exercise Improves Alzheimer’s Disease Phenotype in the TgF344-AD Rat, a Behavioral Time Course Study of Males and Females
    Stephanie E. Hall, Zachary J. White, Troy T. Rohn, Keshari Sudasinghe, Michael E. Young · 2025 · Brain Sciences
35. Tau Exon 10 Inclusion by PrPC through Downregulating GSK3β Activity
    Laia Lidón, Laura Llaó-Hierro, Mario Nuvolone, Adriano Aguzzi, Jesús Ávila, Isidró Ferrer, José Antonio del Rı́o, Rosalina Gavı́n · 2021 · International Journal of Molecular Sciences
36. The TAU isoform 1N4R restores vulnerability of MAPT knockout human iPSC-derived neurons to Amyloid beta-induced neuronal dysfunction
    Sarah Buchholz, Michael J. Bell, Mhd. Aghyad Al Kabbani, Lena Kluge, Cagla Cagkmak, Jennifer Klimek, Hans Zempel · 2022 · Research Square
37. Telomere-driven senescence accelerates tau pathology, neuroinflammation and neurodegeneration in a tauopathy mouse model
    Debora Palomares, Axelle Vanparys, Joana Jorgji, Esther Paître, Pascal Kienlen‐Campard, Núria Suelves · 2025 · Acta Neuropathologica Communications
38. The role of microtubule-associated protein tau in netrin-1 attractive signaling
    Huai Huang, Tanushree Majumder, Bhakti Khot, Harindi Suriyaarachchi, Tao Yang, Qiangqiang Shao, Shraddha Tirukovalluru, Guofa Liu · 2024 · Journal of Cell Science
39. Differences in Tau Seeding in Newborn and Adult Wild-Type Mice
    Isidró Ferrer, Pol Andrés‐Benito, Paula Garcia‐Esparcia, Irene López‐González, Diego Valiente, Mónica Jordán, Margarita Carmona, Julia Sala‐Jarque, Vanessa Gil, José Antonio del Rı́o · 2022 · International Journal of Molecular Sciences
40. A liquid chromatography tandem mass spectroscopy approach for quantification of protein methylation stoichiometry
    Grace L. Cooper, Carol J. Huseby, Claire N. Chandler, Jean‐Christophe Cocuron, Ana Paula Alonso, Jeff Kuret · 2018 · Analytical Biochemistry
41. Minimalistic in vitro systems for investigating tau pathology
    Grace I. Hallinan, Aleksandra P. Pitera, Prutha Patel, Jonathan J. West, Katrin Deinhardt · 2018 · Journal of Neuroscience Methods
42. Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Molecular Brain
43. Treatment with Tau fibrils impact Huntington's disease-related phenotypes in cell and mouse models
    Shireen Salem, Melanie Alpaugh, Martine Saint‐Pierre, Flávia Natale Borba, Catalina Cerquera‐Cleves, Mado Lemieux, Soki Bradel Ngonza-Nito, Paul De Koninck, Ronald Melki, Francesca Cicchetti · 2024 · Neurobiology of Disease
44. Diverse Efficacy of Dimethyl Fumarate in Alleviating the Late Streptozotocin-Induced Cognitive Impairment and Neuropathological Features in Rat
    Irena Majkutewicz, E. Kurowska, Jan Ruciński, Dorota Myślińska, Beata Grembecka, Jagoda Mantej, Katarzyna Patrycja Dzik · 2024 · Molecular Neurobiology
45. Cryo-EM structure of pro-aggregant P301L/S320F double-mutant tau filaments formed in mouse brains following peripheral AAV delivery
    Maria Kano, 木村 妙子, Haruaki Yanagisawa, Komei Yamashita, Lisa Tatsumi, Asahi Sakai, Xinyi Li, Takaomi C. Saido, Takashi Saito, Sho Takatori et al. · 2026 · Acta Neuropathologica Communications
46. Targeted Nano-based Drug Delivery in Alzheimer's Disease and Dementia
    Payel Mal, Santosh Kumar Rath, Tripti Halder · 2024 · Smart nanomaterials technology
47. Tauopathy in the APP swe / PS1 ΔE9 mouse model of familial Alzheimer’s disease
    Athanasios Metaxas, Camilla Thygesen, Stefan J. Kempf, M Anzalone, Ramanan Vaitheeswaran, Sussanne Petersen, Anne Marlene Landau, Hélène Audrain, Jessica L. Teeling, Sultan Darvesh et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
48. Scalable human neuronal models of tauopathy producing endogenous seed-competent 4R tau
    Eliona Tsefou, Sumi Bez, Timothy J.Y. Birkle, Martha S. Foiani, Naoto Watamura, Mathieu Bourdenx, Daria Gavriouchkina, Emir Turkes, Samuel Crawford, Rachel Coneys et al. · 2026 · Science Advances
49. Differential effects of tau expression on seizures and epileptogenesis in a mouse model of temporal lobe epilepsy
    Madeleine C. Moseley, Ryan Cloyd, Liam Burns, Rafael Roberts, Young‐Jin Kang, Sang-Hun Lee, Bret N. Smith · 2025 · Frontiers in Systems Neuroscience
50. 4R-tau isoform induction via TDP-43 in neurons in response to insulin: converging signaling pathways with implications for neurodegenerative disease
    Carina Weissmann, Libia Catalina Salinas Castellanos, Mayra Micaela Montes, Gӧkhan Uruk, Hossam Youssef, Robert Ross Reichard, Rodolfo G. Gatto, Keith A. Josephs · 2025 · Acta Neuropathologica Communications
51. Spontaneous tauopathy with parkinsonism in an aged cynomolgus macaque
    Mirai Takahashi, Daisuke Taniguchi, Manabu Funayama, Ettore Cioffi, Shusei Fukuyama, T. Ito, Toshi Nakajima, Ko Tsuyama, Yuanzhe Li, Satoshi Ishiko et al. · 2026 · Frontiers in Aging Neuroscience
52. Tau Pathology
    Nicolas Sergeant, Luc Buée · 2010 · Advances in neurobiology
53. Patient-derived tau-seeded human neuronal chimeras recapitulate mature Alzheimer’s tau pathology and uncover human-specific neuronal vulnerability
    Yanru Ji, Purba Mandal, Jiahui Liu, Wen Hu, Bryce David Colon, Changlin Wan, Raymond W. Pan, Dongkai Guo, Lijia Zhang, Xingjian Gu et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
54. Exploring the transcriptome of the brain
    Allissa Dillman · 2014 · Figshare
55. The Microtubule-Dissociating Tau in Neurological Disorders
    Francisco Jos, Susanna Schraen‐Maschke, Luc Buée · 2012 · InTech eBooks
56. Mouse and stem cell models of frontotemporal dementia
    Miranda E. Orr · 2012 · Montana State University ScholarWorks (Montana State University)
57. Familial Danish dementia young Knock-in rats expressing humanized APP and human Aβ show impaired pre and postsynaptic glutamatergic transmission
    Tao Yin, Wen Yao, Kelly A. Norris, Luciano D'adamio · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
58. The Role of Microglial-Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) in Neuronal Homeostasis and Tau Pathogenesis
    Vaishnavi Jadhav · 2021 · IUScholarWorks (Indiana University)
59. TAU Models
    Nicolas Sergeant, Luc Buée · 2010 · Neuromethods
60. Extracellular Tau Oligomers Induce Disruption of Endogenous Tau Distribution, Invasion of Tau into the Somatodendritic Compartment and Axonal Transport Dysfunction
    Eric C Swanson · 2017
61. The contribution of oligodendrocytes to amyloid and tau pathologies in mouse models of Alzheimer’s disease
    Andrew Octavian Sasmita · 2024 · eDiss (Georg-August-Universität Göttingen)
62. Adult Neurogenesis
    Matthew Shtrahman, Sarah Parylak, Tomohisa Toda, Fred H. Gage · 2025 · Oxford University Press eBooks
63. Tau deletion results in sex-dependent modulation of synaptic weakening in rat hippocampus
    Liam T. Ralph, Patrick Tidball, Eric W. Salter, Brian Park, Lijia Zhang, Mengdi Wei, Lauren A. Joe, Jonathan S. Thacker, Sun-Lim Choi, Ashish Kadia et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
64. Use of rodent models in drug discovery for Alzheimer’s disease
    James E. Barrett, Joanne R. Mathiasen, Paul McGonigle · 2025 · Elsevier eBooks
65. Additional file 3 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
66. Additional file 2 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
67. Additional file 6 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
68. Additional file 1 of Transmission of amyloid-beta and tau pathologies is associated with cognitive impairments in a primate
    Suzanne Lam, Fanny Petit, Anne‐Sophie Hérard, Susana Boluda, Sabiha Eddarkaoui, Martine Guillermier, Luc Buée, Charles J. Duyckaerts, Stéphane Haı̈k, Jean‐Luc Picq et al. · 2021 · Figshare
69. Additional file 1 of Reassessment of Neuronal Tau Distribution in Adult Human Brain and Implications for Tau Pathobiology
    Giavanna Paterno, Brach M. Bell, Gorion, Kimberly-Marie M., Stefan Prokop, Benoit I. Giasson · 2022 · Figshare
70. Additional file 7 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
71. Additional file 1 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
72. Additional file 8 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
73. Additional file 4 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
74. Additional file 5 of Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage
    Emma F. Jones, Timothy C. Howton, Victoria L. Flanary, Amanda D. Clark, Brittany N. Lasseigne · 2024 · Figshare
75. Tau nucléaire : un acteur clé dans le stress neuronal
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76. The role of serotoninergic neurons in amyotrophic lateral sclerosis
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77. Identification et caractérisation des modifications post-traductionnelles de la protéine TAU : implication dans le processus d'agrégation
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78. Conditional truncation of the FUS protein in mice : a new animal model of the ALS/FTD continuum
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79. Rôle de la neuroinflammation et du récepteur microglial TREM2 dans la progression de deux modèles de tauopathie
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80. Study of the Neuron-Astrocyte Relationship in a Rodent Model of Tauopathy
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81. Novel FUS and CHCHD10 models to investigate pathogenic mechanisms in Amyotrophic Lateral Sclerosis
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82. Étude du rôle de la microglie dans la propagation de la protéine Tau : mise en place de nouveaux modèles
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83. Transmission of Alzheimer pathology in murine and primate models : from proteinopathies to neuronal and cognitive impairments
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84. Astrocytes dysfunction in tauopathies
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85. Vertebrate Animal Models of Primary 4-Repeat Tauopathies
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86. CELF2 promotes 4R Tau splicing via nuclear clustering and drives cognitive dysfunction in tauopathy models
    Xin Li, I SYED, Rashmi Adhikari, Jing Jiang, Yu Zhang, Dan Tang, Su Hyuk Ko, Zhao Zhang, Zhijie Liu, Lizhen Chen · 2026 · Nature Communications